Page last updated: 2024-11-03

probenecid and Pseudoxanthoma Elasticum

probenecid has been researched along with Pseudoxanthoma Elasticum in 2 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Pseudoxanthoma Elasticum: An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Iliás, A1
Urbán, Z1
Seidl, TL1
Le Saux, O1
Sinkó, E1
Boyd, CD1
Sarkadi, B1
Váradi, A1
Osti, MH1
Scardamaglia, L1

Other Studies

2 other studies available for probenecid and Pseudoxanthoma Elasticum

ArticleYear
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).
    The Journal of biological chemistry, 2002, May-10, Volume: 277, Issue:19

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport; Blotting, Western;

2002
Treatment of pseudoxanthoma elasticum with probenecid.
    The Australasian journal of dermatology, 2021, Volume: 62, Issue:3

    Topics: Adult; Female; Humans; Probenecid; Pseudoxanthoma Elasticum; Treatment Outcome; Uricosuric Agents

2021