probenecid has been researched along with Pre-Eclampsia in 4 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidemiological characteristics of preeclampsia such as its uniqueness to humans and an increased incidence of preeclampsia in multiple pregnancies, increased body mass index, renal and hypertensive disease all have uric acid as their common denominator." | 2.71 | Hyperuricaemia and preeclampsia: is there a pathogenic link? ( Schackis, RC, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HAYASHI, TT | 2 |
| CZACZKES, WJ | 1 |
| ULLMANN, TD | 1 |
| SADOWSKY, E | 1 |
| BATT, RE | 1 |
| CIRKSENA, WJ | 1 |
| LEBHERZ, TB | 1 |
| Schackis, RC | 1 |
1 trial available for probenecid and Pre-Eclampsia
| Article | Year |
|---|---|
Hyperuricaemia and preeclampsia: is there a pathogenic link?
Topics: Adult; Blood Pressure; Creatine; Female; Humans; Hyperuricemia; Platelet Count; Pre-Eclampsia; Pregn | 2004 |
3 other studies available for probenecid and Pre-Eclampsia
| Article | Year |
|---|---|
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
Plasma uric acid levels, uric acid excretion, and response to probenecid in toxemia of pregnancy.
Topics: Biological Transport; Body Fluids; Female; Humans; Plasma; Pre-Eclampsia; Pregnancy; Probenecid; Uri | 1958 |
GOUT AND SALT-WASTING RENAL DISEASE DURING PREGNANCY; DIAGNOSIS, MANAGEMENT, AND FOLLOW-UP.
Topics: Blood Chemical Analysis; Colchicine; Diet Therapy; Diet, Sodium-Restricted; Female; Follow-Up Studie | 1963 |