probenecid has been researched along with Polycystic Kidney, Autosomal Dominant in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Development of autosomal dominant polycystic kidney disease (ADPKD) involves renal epithelial cell abnormalities." | 5.91 | Probenecid slows disease progression in a murine model of autosomal dominant polycystic kidney disease. ( Arkhipov, SN; Harris, PC; Ilatovskaya, DV; Pavlov, TS; Potter, DL; Sultanova, RF, 2023) |
| "Development of autosomal dominant polycystic kidney disease (ADPKD) involves renal epithelial cell abnormalities." | 1.91 | Probenecid slows disease progression in a murine model of autosomal dominant polycystic kidney disease. ( Arkhipov, SN; Harris, PC; Ilatovskaya, DV; Pavlov, TS; Potter, DL; Sultanova, RF, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arkhipov, SN | 1 |
| Potter, DL | 1 |
| Sultanova, RF | 1 |
| Ilatovskaya, DV | 1 |
| Harris, PC | 1 |
| Pavlov, TS | 1 |
| Tanner, GA | 1 |
| Sandoval, RM | 1 |
| Dunn, KW | 1 |
2 other studies available for probenecid and Polycystic Kidney, Autosomal Dominant
| Article | Year |
|---|---|
Probenecid slows disease progression in a murine model of autosomal dominant polycystic kidney disease.
Topics: Adenosine Triphosphate; Animals; Cysts; Disease Models, Animal; Disease Progression; Female; Humans; | 2023 |
Two-photon in vivo microscopy of sulfonefluorescein secretion in normal and cystic rat kidneys.
Topics: Animals; Fluoresceins; Kidney Tubules, Proximal; Male; Microscopy, Fluorescence; Polycystic Kidney, | 2004 |