Page last updated: 2024-11-03

probenecid and Phlegmon

probenecid has been researched along with Phlegmon in 5 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Research Excerpts

ExcerptRelevanceReference
"A once-daily regimen of cefazolin (2 g intravenously [iv]) plus probenecid (1 g by mouth) was compared with a once-daily regimen of ceftriaxone (1 g iv) plus oral placebo in a randomized, double-blind equivalence trial of home-based therapy for moderate-to-severe cellulitis in adults."9.10Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderate-to-severe cellulitis in adults. ( Athan, E; Chambers, F; Gibson, K; Grayson, ML; McDonald, M; Munckhof, WJ; Paull, P, 2002)
"Once-daily intravenous cefazolin with probenecid is used commonly to treat cellulitis."7.77Risk factors of cellulitis treatment failure with once-daily intravenous cefazolin plus oral probenecid. ( Bader, MS; Hawboldt, J; Twells, L, 2011)
"A once-daily regimen of cefazolin (2 g intravenously [iv]) plus probenecid (1 g by mouth) was compared with a once-daily regimen of ceftriaxone (1 g iv) plus oral placebo in a randomized, double-blind equivalence trial of home-based therapy for moderate-to-severe cellulitis in adults."5.10Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderate-to-severe cellulitis in adults. ( Athan, E; Chambers, F; Gibson, K; Grayson, ML; McDonald, M; Munckhof, WJ; Paull, P, 2002)
"Once-daily intravenous cefazolin with probenecid is used commonly to treat cellulitis."3.77Risk factors of cellulitis treatment failure with once-daily intravenous cefazolin plus oral probenecid. ( Bader, MS; Hawboldt, J; Twells, L, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bader, MS1
Twells, L1
Hawboldt, J1
Edwards, J1
Green, P1
Haase, D1
Khangura, S1
Wallace, J1
Kissoon, N1
Kodeeswaran, T1
Grayson, ML1
McDonald, M1
Gibson, K1
Athan, E1
Munckhof, WJ1
Paull, P1
Chambers, F1
Bodey, GP1
Rodriguez, V1
Luce, JK1

Trials

1 trial available for probenecid and Phlegmon

ArticleYear
Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderate-to-severe cellulitis in adults.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Jun-01, Volume: 34, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Cefazolin; Ceftriaxone; Cellulitis

2002

Other Studies

4 other studies available for probenecid and Phlegmon

ArticleYear
Risk factors of cellulitis treatment failure with once-daily intravenous cefazolin plus oral probenecid.
    Southern medical journal, 2011, Volume: 104, Issue:12

    Topics: Administration, Oral; Anti-Bacterial Agents; Cefazolin; Cellulitis; Chi-Square Distribution; Drug Th

2011
A blistering disease: bullous erysipelas.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2006, Aug-01, Volume: 175, Issue:3

    Topics: Anti-Bacterial Agents; Blister; Cefazolin; Cellulitis; Diabetes Mellitus, Type 2; Erysipelas; Humans

2006
Management of cellulitis in a pediatric emergency department.
    Pediatric emergency care, 2007, Volume: 23, Issue:11

    Topics: Academic Medical Centers; Adjuvants, Pharmaceutic; Administration, Oral; Adolescent; Anti-Bacterial

2007
Carbenicillin therapy of gram-negative bacilli infections.
    The American journal of the medical sciences, 1969, Volume: 257, Issue:6

    Topics: Adolescent; Cellulitis; Child; Enterobacteriaceae Infections; Escherichia coli Infections; Humans; K

1969