probenecid has been researched along with Pancytopenia in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with rheumatoid arthritis developed life-threatening pancytopenia resulting from low dose oral methotrexate (MTX) toxicity potentiated by probenecid." | 7.68 | Severe pancytopenia in a patient taking low dose methotrexate and probenecid. ( Basin, KS; Beardmore, TD; Escalante, A, 1991) |
| "A patient with rheumatoid arthritis developed life-threatening pancytopenia resulting from low dose oral methotrexate (MTX) toxicity potentiated by probenecid." | 3.68 | Severe pancytopenia in a patient taking low dose methotrexate and probenecid. ( Basin, KS; Beardmore, TD; Escalante, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basin, KS | 1 |
| Escalante, A | 1 |
| Beardmore, TD | 1 |
1 other study available for probenecid and Pancytopenia
| Article | Year |
|---|---|
Severe pancytopenia in a patient taking low dose methotrexate and probenecid.
Topics: Aged; Arthritis, Rheumatoid; Blood Cell Count; Dose-Response Relationship, Drug; Drug Interactions; | 1991 |