probenecid has been researched along with Obesity in 10 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 2,923 elderly subjects were studied to determine the relationship between obesity, hypertension, thyroid disease, renal function, alcohol consumption, selected drugs, and the serum uric acid level." | 3.66 | Selected physiologic and drug effects on serum uric acid levels in an elderly population. ( Hale, WE; Marks, RG; Stewart, RB; Yost, RL, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soletsky, B | 1 |
| Feig, DI | 1 |
| CRISTOFORI, FC | 1 |
| DUNCAN, GG | 2 |
| Yost, RL | 1 |
| Stewart, RB | 1 |
| Hale, WE | 1 |
| Marks, RG | 1 |
| Bassett, DR | 1 |
| Mikkelsen, WM | 1 |
| Buckingham, RB | 1 |
| Block, WD | 1 |
| Sidiq, M | 1 |
| Shakibai, A | 1 |
| DiGaetano, R | 1 |
| Liou, LL | 1 |
| Gibson, T | 2 |
| Kilbourn, K | 1 |
| Horner, I | 1 |
| Simmonds, HA | 1 |
| Schräpler, P | 2 |
| Kleinschmidt, A | 1 |
| Haese, E | 1 |
| Schulz, E | 1 |
| Grahame, R | 1 |
| Duncan, TG | 1 |
| Schatanoff, J | 1 |
| Klotz, H | 1 |
| Prohaska, E | 1 |
| Salmhofer, H | 1 |
| Schmid, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00288158] | Phase 2 | 60 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for probenecid and Obesity
| Article | Year |
|---|---|
Uric acid reduction rectifies prehypertension in obese adolescents.
Topics: Adolescent; Allopurinol; Blood Pressure; Child; Double-Blind Method; Drug Administration Schedule; F | 2012 |
Effects of halofenate and probenecid on serum lipids and uric acid in hyperlipidemic, hyperuricemic adults.
Topics: Adult; Aged; Body Weight; Cholesterol; Clinical Trials as Topic; Female; Glycolates; Halofenate; Hum | 1977 |
[The effect of benzbromarone on fasting-hyperuricemia as a model (author's transl)].
Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Humans; Male; Middle Aged; Obesity; | 1978 |
Refractory obesity and diabetes.
Topics: Adult; Body Weight; Diabetes Mellitus; Diet, Diabetic; Fasting; Female; Glucose Tolerance Test; Huma | 1968 |
6 other studies available for probenecid and Obesity
| Article | Year |
|---|---|
URIC ACID EXCRETION IN OBESE SUBJECTS DURING PERIODS OF TOTAL FASTING.
Topics: Acidosis; Basal Metabolism; Blood Glucose; Fasting; Glycine; Humans; Obesity; Pennsylvania; Probenec | 1964 |
Selected physiologic and drug effects on serum uric acid levels in an elderly population.
Topics: Aged; Allopurinol; Diuretics; Female; Humans; Hypertension; Male; Obesity; Probenecid; Thyroid Disea | 1981 |
Mechanism and treatment of hypertriglyceridaemia in gout.
Topics: Alcohol Drinking; Allopurinol; Cholesterol; Gout; Humans; Hyperlipidemias; Male; Middle Aged; Obesit | 1979 |
[Pathogenesis of hyperuricemia and its treatment by means of rigorous fasting (so-called null-diet)].
Topics: Allopurinol; Fasting; Humans; Obesity; Probenecid; Uric Acid | 1976 |
Gout and hyperlipidaemia.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Aspartate Aminotransferases; Body Height; Body Weight; C | 1974 |
[Gout from the view of a special hospital for rheumatic patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Austria; Child; Cholesterol; Colchicine; Colic; Diabetes Com | 1971 |