probenecid has been researched along with Necrosis in 5 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia." | 3.70 | Exercise-induced acute renal failure in a patient with renal hypouricemia. ( Abe, T; Oda, Y; Watanabe, T, 2000) |
| " Probenecid pretreatment led to a reduction in Tris-BP and Bis-BP tubular necrosis, these effects may be related to inhibition of Bis-BP uptake in the kidney." | 3.67 | Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat. ( Dahl, JE; Dybing, E; Nelson, SD; Omichinski, JG; Søderlund, EJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, T | 1 |
| Abe, T | 1 |
| Oda, Y | 1 |
| Monks, TJ | 1 |
| Jones, TW | 1 |
| Hill, BA | 1 |
| Lau, SS | 1 |
| Søderlund, EJ | 2 |
| Omichinski, JG | 2 |
| Dahl, JE | 2 |
| Nelson, SD | 2 |
| Dybing, E | 2 |
| Brunborg, G | 1 |
| Bausano, JA | 1 |
| Holme, JA | 1 |
| Müller, E | 1 |
| Löhr, E | 1 |
5 other studies available for probenecid and Necrosis
| Article | Year |
|---|---|
Exercise-induced acute renal failure in a patient with renal hypouricemia.
Topics: Acute Kidney Injury; Child; Creatinine; Exercise; Follow-Up Studies; Humans; Kidney; Kidney Tubules; | 2000 |
Nephrotoxicity of 2-bromo-(cystein-S-yl) hydroquinone and 2-bromo-(N-acetyl-L-cystein-S-yl) hydroquinone thioethers.
Topics: Aminooxyacetic Acid; Animals; Cysteine; Hydroquinones; Kidney; Kidney Diseases; Male; Necrosis; Prob | 1991 |
Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Gas Chromatography-Mass Spectrometry; Glutath | 1988 |
Renal necrosis and DNA damage caused by selectively deuterated and methylated analogs of 1,2-dibromo-3-chloropropane in the rat.
Topics: Aminooxyacetic Acid; Animals; Cell Nucleus; Deuterium; DNA Damage; Glutathione; Isoxazoles; Kidney; | 1987 |
[Uric arthritis of the hip joint. Differential diagnosis of the idiopathic femur head necrosis].
Topics: Adult; Diagnosis, Differential; Femur Head; Gout; Hip Joint; Humans; Male; Necrosis; Phenylbutazone; | 1969 |