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probenecid and Necrosis

probenecid has been researched along with Necrosis in 5 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia."3.70Exercise-induced acute renal failure in a patient with renal hypouricemia. ( Abe, T; Oda, Y; Watanabe, T, 2000)
" Probenecid pretreatment led to a reduction in Tris-BP and Bis-BP tubular necrosis, these effects may be related to inhibition of Bis-BP uptake in the kidney."3.67Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat. ( Dahl, JE; Dybing, E; Nelson, SD; Omichinski, JG; Søderlund, EJ, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watanabe, T1
Abe, T1
Oda, Y1
Monks, TJ1
Jones, TW1
Hill, BA1
Lau, SS1
Søderlund, EJ2
Omichinski, JG2
Dahl, JE2
Nelson, SD2
Dybing, E2
Brunborg, G1
Bausano, JA1
Holme, JA1
Müller, E1
Löhr, E1

Other Studies

5 other studies available for probenecid and Necrosis

ArticleYear
Exercise-induced acute renal failure in a patient with renal hypouricemia.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:8-9

    Topics: Acute Kidney Injury; Child; Creatinine; Exercise; Follow-Up Studies; Humans; Kidney; Kidney Tubules;

2000
Nephrotoxicity of 2-bromo-(cystein-S-yl) hydroquinone and 2-bromo-(N-acetyl-L-cystein-S-yl) hydroquinone thioethers.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Cysteine; Hydroquinones; Kidney; Kidney Diseases; Male; Necrosis; Prob

1991
Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat.
    Pharmacology & toxicology, 1988, Volume: 62, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Gas Chromatography-Mass Spectrometry; Glutath

1988
Renal necrosis and DNA damage caused by selectively deuterated and methylated analogs of 1,2-dibromo-3-chloropropane in the rat.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Cell Nucleus; Deuterium; DNA Damage; Glutathione; Isoxazoles; Kidney;

1987
[Uric arthritis of the hip joint. Differential diagnosis of the idiopathic femur head necrosis].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1969, Volume: 111, Issue:5

    Topics: Adult; Diagnosis, Differential; Femur Head; Gout; Hip Joint; Humans; Male; Necrosis; Phenylbutazone;

1969