probenecid has been researched along with Narcolepsy in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Faull, KF | 1 |
Barchas, JD | 2 |
Foutz, AS | 2 |
Dement, WC | 3 |
Holman, RB | 2 |
Guilleminault, C | 1 |
Phillips, R | 1 |
Faull, K | 1 |
3 other studies available for probenecid and Narcolepsy
Article | Year |
---|---|
Monoamine metabolite concentrations in the cerebrospinal fluid of normal and narcoleptic dogs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Dogs; Homovanillic Acid; Humans; Hydroxyin | 1982 |
A syndrome of hypersomnia with automatic behavior.
Topics: Adult; Attention; Automatism; Circadian Rhythm; Electroencephalography; Homovanillic Acid; Humans; H | 1975 |
The concentrations of amine metabolites in cerebrospinal fluid from normal and narcoleptic dogs [proceedings].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dogs; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; | 1979 |