probenecid has been researched along with Myocardial Ischemia in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Onódi, Z | 2 |
| Koch, S | 2 |
| Rubinstein, J | 3 |
| Ferdinandy, P | 2 |
| Varga, ZV | 2 |
| Koch, SE | 1 |
| Tranter, M | 1 |
| Robbins, N | 1 |
| Luther, K | 1 |
| Singh, U | 1 |
| Jiang, M | 1 |
| Ren, X | 1 |
| Tee, T | 1 |
| Smith, L | 1 |
| Varma, P | 1 |
| Jones, WK | 1 |
1 review available for probenecid and Myocardial Ischemia
| Article | Year |
|---|---|
Drug repurposing for cardiovascular diseases: New targets and indications for probenecid.
Topics: Cardiovascular Diseases; Coronary Artery Disease; Drug Repositioning; Heart Failure; Humans; Myocard | 2023 |
Drug repurposing for cardiovascular diseases: New targets and indications for probenecid.
Topics: Cardiovascular Diseases; Coronary Artery Disease; Drug Repositioning; Heart Failure; Humans; Myocard | 2023 |
Drug repurposing for cardiovascular diseases: New targets and indications for probenecid.
Topics: Cardiovascular Diseases; Coronary Artery Disease; Drug Repositioning; Heart Failure; Humans; Myocard | 2023 |
Drug repurposing for cardiovascular diseases: New targets and indications for probenecid.
Topics: Cardiovascular Diseases; Coronary Artery Disease; Drug Repositioning; Heart Failure; Humans; Myocard | 2023 |
1 other study available for probenecid and Myocardial Ischemia
| Article | Year |
|---|---|
Probenecid as a noninjurious positive inotrope in an ischemic heart disease murine model.
Topics: Administration, Oral; Animals; Calcium Signaling; Cardiotonic Agents; Cell Line; Cell Survival; Dise | 2013 |