probenecid has been researched along with Metabolism, Inborn Errors in 4 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Metabolism, Inborn Errors: Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid did not inhibit folate binding to FR, but inhibited PCFT-mediated transport at endosomal pH, and blocked FRalpha-mediated transport into the cytosol." | 1.35 | A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis. ( Campanella, E; Goldman, ID; Low, PS; Min, SH; Wang, Y; Zhao, R, 2009) |
| "Hematuria was seen in 7 out of the 16 patients (44%), all of whom were females (58%)." | 1.30 | Hematuria in patients with renal hypouricemia. ( Hamada, N; Hiroe, K; Hisatome, I; Kato, T; Kinugawa, T; Manabe, I; Ogino, K; Ohtahara, A; Sato, R; Shigemasa, C; Shimoyama, M; Takeda, A; Tanaka, Y; Tsuboi, M; Yamamoto, Y; Yoshida, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, R | 1 |
| Min, SH | 1 |
| Wang, Y | 1 |
| Campanella, E | 1 |
| Low, PS | 1 |
| Goldman, ID | 1 |
| Tanaka, M | 1 |
| Itoh, K | 1 |
| Matsushita, K | 2 |
| Wakita, N | 1 |
| Adachi, M | 1 |
| Nonoguchi, H | 1 |
| Kitamura, K | 1 |
| Hosoyamada, M | 1 |
| Endou, H | 1 |
| Tomita, K | 1 |
| Hisatome, I | 1 |
| Tanaka, Y | 1 |
| Ogino, K | 1 |
| Shimoyama, M | 1 |
| Hiroe, K | 1 |
| Tsuboi, M | 1 |
| Yamamoto, Y | 1 |
| Hamada, N | 1 |
| Kato, T | 1 |
| Manabe, I | 1 |
| Kinugawa, T | 1 |
| Ohtahara, A | 1 |
| Yoshida, A | 1 |
| Shigemasa, C | 1 |
| Takeda, A | 1 |
| Sato, R | 1 |
4 other studies available for probenecid and Metabolism, Inborn Errors
| Article | Year |
|---|---|
A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis.
Topics: Biological Transport, Active; Carrier Proteins; Cytosol; Endocytosis; Endosomes; Folate Receptors, G | 2009 |
Two male siblings with hereditary renal hypouricemia and exercise-induced ARF.
Topics: Acute Kidney Injury; Adult; Back Pain; Carrier Proteins; Codon, Nonsense; Creatinine; Exercise; Exon | 2003 |
Hematuria in patients with renal hypouricemia.
Topics: Adult; Aged; Aged, 80 and over; Benzbromarone; Creatinine; Female; Hematuria; Humans; Kidney Disease | 1998 |
Hemolytic anemia complicating viral hepatitis and G-6-PD deficiency.
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Congenital; Aspirin; Glucosephosphate Dehydrogenase Deficiency | 1969 |