probenecid has been researched along with Metabolic Acidosis in 10 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urobilinogen is a weak acid, and this mode of excretion is similar to that of other weak, organic acids, such as salicylates." | 1.25 | Renal excretion of urobilinogen in the dog. ( Lester, R; Levinsky, NG; Levy, M, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CRISTOFORI, FC | 1 |
| DUNCAN, GG | 1 |
| Constant, MA | 2 |
| Musil, J | 1 |
| Frey, HH | 1 |
| Löscher, W | 1 |
| Dash, H | 1 |
| Mills, J | 1 |
| Nakata, T | 1 |
| Iimura, O | 1 |
| Varma, DR | 1 |
| Levy, M | 1 |
| Lester, R | 1 |
| Levinsky, NG | 1 |
| Gussin, RZ | 1 |
| Cummings, JR | 1 |
| Stokey, EH | 1 |
| Ronsberg, MA | 1 |
10 other studies available for probenecid and Metabolic Acidosis
| Article | Year |
|---|---|
URIC ACID EXCRETION IN OBESE SUBJECTS DURING PERIODS OF TOTAL FASTING.
Topics: Acidosis; Basal Metabolism; Blood Glucose; Fasting; Glycine; Humans; Obesity; Pennsylvania; Probenec | 1964 |
Distribution of 5,5 dimethyl-2,4-oxazolidinedione (DMO) in intraocular and cerebrospinal fluids of rabbits. 3. Effect of ammonium chloride and probenecid.
Topics: Acidosis; Ammonium Chloride; Animals; Aqueous Humor; Biological Transport; Cerebrospinal Fluid; Hydr | 1967 |
Distribution of 5,5 dimethyl-2,4-oxazolidinedione in intraocular fluids of rabbits. IV. Distribution of probenecid.
Topics: Acidosis; Ammonium Chloride; Animals; Aqueous Humor; Biological Transport, Active; Dichlorphenamide; | 1967 |
Physiological characteristics of various experimental models for the study of disorders in purine metabolism.
Topics: Acidosis; Alkalosis; Allopurinol; Animals; Cholesterol; Disease Models, Animal; Diuresis; Fructose; | 1977 |
Distribution of valproate across the interface between blood and cerebrospinal fluid.
Topics: Acidosis; Animals; Dogs; Drug Interactions; Female; Kinetics; Male; Phenylbutazone; Probenecid; Prot | 1978 |
Letter: Severe metabolic acidosis associated with nalidixic acid overdose.
Topics: Acidosis; Adolescent; Drug Interactions; Humans; Male; Nalidixic Acid; Probenecid | 1976 |
[The management of hyperuricemia associated with drug treatment of hypertension].
Topics: Acidosis; Adrenergic beta-Antagonists; Allopurinol; Antihypertensive Agents; Benzothiadiazines; Diur | 1992 |
Modification of transplacental distribution of salicylate in rats by acidosis and alkalosis.
Topics: Acidosis; Alkalosis; Ammonium Chloride; Animals; Bicarbonates; Blood Gas Analysis; Female; Hydrogen- | 1988 |
Renal excretion of urobilinogen in the dog.
Topics: Acidosis; Alkalosis; Animals; Diuresis; Dogs; Female; Hydrogen-Ion Concentration; Kidney; Kidney Glo | 1968 |
CL 65,562 (4-(a,a,a-trifluoro-m-toluidino)-nicotinic acid), a novel "high ceiling" diuretic.
Topics: Acidosis; Aminohippuric Acids; Animals; Chemical Phenomena; Chemistry; Chlorides; Diuresis; Diuretic | 1969 |