probenecid has been researched along with Leukemia in 7 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SIPOS, J | 1 |
| HAJDU, G | 1 |
| Dogan, AL | 1 |
| Legrand, O | 1 |
| Faussat, AM | 1 |
| Perrot, JY | 1 |
| Marie, JP | 1 |
| Rosati, A | 1 |
| Candussio, L | 1 |
| Crivellato, E | 1 |
| Klugmann, FB | 1 |
| Giraldi, T | 1 |
| Damiani, D | 1 |
| Michelutti, A | 1 |
| Decorti, G | 1 |
| Henderson, GB | 1 |
| Tsuji, JM | 1 |
| Kumar, HP | 1 |
| Tattersall, MH | 1 |
| Spiers, AS | 1 |
| Darrell, JH | 1 |
| Bodey, GP | 1 |
| Rodriguez, V | 1 |
| Stewart, D | 1 |
| Eickhoff, TC | 1 |
| Marks, MI | 1 |
7 other studies available for probenecid and Leukemia
| Article | Year |
|---|---|
DECREASE OF PLASMA URIC ACID CONCENTRATION OF SUBJECTS WITH LEUKEMIA BY BENEMID.
Topics: Blood; Drug Therapy; Humans; Leukemia; Probenecid; Uric Acid | 1964 |
Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bronchodilator Agents | 2004 |
Bodipy-FL-verapamil: a fluorescent probe for the study of multidrug resistance proteins.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological | 2004 |
Characterization of the individual transport routes that mediate the influx and efflux of methotrexate in CCRF-CEM human lymphoblastic cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; | 1986 |
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections | 1972 |
Clinical pharmacological studies of carbenicillin.
Topics: Adult; Aged; Humans; Injections, Intravenous; Kidney Function Tests; Leukemia; Lymph; Middle Aged; N | 1969 |
Carbenicillin in therapy of systemic infections due to Pseudomonas.
Topics: Anti-Bacterial Agents; Benzene Derivatives; Humans; Injections, Intravenous; Leukemia; Penicillins; | 1970 |