probenecid has been researched along with Intraocular Pressure in 6 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-dependent asymptomatic proteinuria (39%) and serum creatinine elevation (24%) were the most common adverse events thought to be related to cidofovir." | 2.69 | Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS. ( Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M, 1998) |
| "Eligible patients with acquired immune deficiency syndrome had active CMV retinitis in at least one eye and no evidence of extraocular CMV disease." | 2.68 | Intravitreal cidofovir (HPMPC) treatment of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome. ( Arevalo, JF; Chavez de la Paz, E; de Clercq, E; Freeman, WR; Kirsch, LS; Munguia, D, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pattabiraman, PP | 1 |
| Pecen, PE | 1 |
| Rao, PV | 1 |
| Kirsch, LS | 1 |
| Arevalo, JF | 1 |
| Chavez de la Paz, E | 1 |
| Munguia, D | 1 |
| de Clercq, E | 1 |
| Freeman, WR | 1 |
| Lalezari, JP | 1 |
| Holland, GN | 1 |
| Kramer, F | 1 |
| McKinley, GF | 1 |
| Kemper, CA | 1 |
| Ives, DV | 1 |
| Nelson, R | 1 |
| Hardy, WD | 1 |
| Kuppermann, BD | 1 |
| Northfelt, DW | 1 |
| Youle, M | 1 |
| Johnson, M | 1 |
| Lewis, RA | 1 |
| Weinberg, DV | 1 |
| Simon, GL | 1 |
| Wolitz, RA | 1 |
| Ruby, AE | 1 |
| Stagg, RJ | 1 |
| Jaffe, HS | 1 |
| Scott, RA | 1 |
| Pavesio, C | 1 |
| Podos, SM | 1 |
| Raviola, G | 1 |
| Butler, JM | 1 |
2 trials available for probenecid and Intraocular Pressure
| Article | Year |
|---|---|
Intravitreal cidofovir (HPMPC) treatment of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; | 1995 |
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; C | 1998 |
4 other studies available for probenecid and Intraocular Pressure
| Article | Year |
|---|---|
MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure.
Topics: Actins; Adult; Aged; Animals; Aqueous Humor; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Prote | 2013 |
Ocular side-effects from systemic HPMPC (Cidofovir) for a non-ocular cytomegalovirus infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto | 2000 |
Prostaglandins, nonsteroidal anti-inflammatory agents and eye disease.
Topics: Animals; Aqueous Humor; Arachidonic Acids; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synerg | 1976 |
Morphological evidence for the transfer of anionic macromolecules from the interior of the eye to the blood stream.
Topics: Animals; Anterior Chamber; Eye; Female; Ferritins; Horseradish Peroxidase; Intraocular Pressure; Mac | 1985 |