probenecid has been researched along with Inappropriate ADH Syndrome in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid was given to two of them and it produced large increases in uric acid clearance." | 1.27 | Renal handling of urate in the syndrome of inappropriate secretion of antidiuretic hormone. ( Kanayama, M; Kijima, Y; Shichiri, M; Shiigai, T; Shinoda, T, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prospert, F | 1 |
| Soupart, A | 1 |
| Brimioulle, S | 1 |
| Decaux, G | 1 |
| Shichiri, M | 2 |
| Shiigai, T | 2 |
| Shinoda, T | 1 |
| Kijima, Y | 1 |
| Kanayama, M | 1 |
3 other studies available for probenecid and Inappropriate ADH Syndrome
| Article | Year |
|---|---|
Evidence of defective tubular reabsorption and normal secretion of uric acid in the syndrome of inappropriate secretion of antidiuretic hormone.
Topics: Absorption; Aged; Female; Humans; Inappropriate ADH Syndrome; Kidney Tubules; Male; Middle Aged; Pro | 1993 |
Hypouricemia in the syndrome of inappropriate secretion of antidiuretic hormone.
Topics: Humans; Inappropriate ADH Syndrome; Metabolic Clearance Rate; Probenecid; Uric Acid | 1986 |
Renal handling of urate in the syndrome of inappropriate secretion of antidiuretic hormone.
Topics: Aged; Female; Humans; Inappropriate ADH Syndrome; Kidney; Male; Metabolic Clearance Rate; Middle Age | 1985 |