probenecid has been researched along with Hypoxia in 11 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor." | 3.65 | Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Vandorpe, DH | 1 |
| Rivera, A | 1 |
| Ganter, M | 1 |
| Dankwa, S | 1 |
| Wohlgemuth, JG | 1 |
| Dlott, JS | 1 |
| Snyder, LM | 1 |
| Brugnara, C | 1 |
| Duraisingh, M | 1 |
| Alper, SL | 1 |
| DESPOPOULOS, A | 2 |
| KOLBER, J | 1 |
| Galli, C | 1 |
| Spagnuolo, C | 1 |
| Petroni, A | 1 |
| Gutman, Y | 1 |
| Wald, H | 1 |
| Czazkes, W | 1 |
| Van Woert, MH | 1 |
| Sethy, VH | 1 |
| Paller, MS | 1 |
| Patten, M | 1 |
| MacMillan, V | 1 |
| Miwa, S | 1 |
| Fujiwara, M | 2 |
| Lee, K | 1 |
| Davis, JN | 1 |
| Carlsson, A | 1 |
| Jones, VD | 1 |
| van Dyke, DH | 1 |
| Cserr, H | 1 |
| Barlow, CF | 1 |
11 other studies available for probenecid and Hypoxia
| Article | Year |
|---|---|
Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes.
Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Apyrase; Cations; Cells, Cultured; Erythrocytes; Humans | 2022 |
NON-COMPETITIVE NON-INHIBITORY INTERACTION BETWEEN HIPPURATE AND CREATININE IN THE KIDNEY.
Topics: Acetates; Animals; Biological Transport; Creatine; Creatinine; Hippurates; Hypoxia; Kidney; Metaboli | 1964 |
Factors affecting brain prostaglandin formation.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Convulsants; Fatty Acids, Essential; Gerbillinae; H | 1980 |
Differences in characteristics of ethacrynic acid accumulation in kidney cortex, medulla and papilla.
Topics: Animals; Ethacrynic Acid; Ethylmaleimide; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; | 1975 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cer | 1975 |
Protective effects of glutathione, glycine, or alanine in an in vitro model of renal anoxia.
Topics: Alanine; Animals; Buthionine Sulfoximine; Cells, Cultured; Glutathione; Glycine; Hypoxia; Ischemia; | 1992 |
Effect of probenecid on cerebral and cisternal cerebrospinal fluid lactate content.
Topics: Animals; Brain; Cisterna Magna; Energy Metabolism; Glucose; Homovanillic Acid; Hydroxyindoleacetic A | 1987 |
Determination of serotonin turnover in the rat brain using 6-fluorotryptophan.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Hypoxia; Male; Probenecid; Rats; Rats, Inbred Strains; Ser | 1987 |
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; | 1973 |
Is uric acid transported by the hippurate transport system?
Topics: Acetates; Animals; Bile; Biological Transport; Carbon Radioisotopes; Hippurates; Hypoxia; In Vitro T | 1974 |
5-Hydroxyindoleacetic acid (5-HIAA) transport by isolated choroid plexus.
Topics: Aminohippuric Acids; Anesthesia; Animals; Biological Transport, Active; Carbon Isotopes; Choroid Ple | 1970 |