Page last updated: 2024-11-03

probenecid and Hyperlipidemias

probenecid has been researched along with Hyperlipidemias in 8 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Hyperlipidemias: Conditions with excess LIPIDS in the blood.

Research Excerpts

ExcerptRelevanceReference
"23 patients with hyperlipidemia and hyperuricemia received acetamidoethyl-(4-chlorophenyl)-(trifluoromethylphenoxy)-acetate (halofenate), a clofibrate derivative, and probenecid or probenecid and placebo over 36 weeks following a placebo period of 6 weeks."6.64[Treatment of hyperlipemia and hyperuricemia with 2-acetamidoethyl-(4-chlorophenyl)-(3-trifluoromethylphenoxy)-acetate (halofenate), a derivative of clofibrate]. ( Keller, C; Wolfram, G; Zöllner, N, 1976)
"Halofenate is a new antilipemic drug which is an ester of carboxylic acid."2.64The metabolic spectrum of halofenate. ( Ryan, JR, 1975)
"23 patients with hyperlipidemia and hyperuricemia received acetamidoethyl-(4-chlorophenyl)-(trifluoromethylphenoxy)-acetate (halofenate), a clofibrate derivative, and probenecid or probenecid and placebo over 36 weeks following a placebo period of 6 weeks."2.64[Treatment of hyperlipemia and hyperuricemia with 2-acetamidoethyl-(4-chlorophenyl)-(3-trifluoromethylphenoxy)-acetate (halofenate), a derivative of clofibrate]. ( Keller, C; Wolfram, G; Zöllner, N, 1976)
"Gout is increasingly recognized as the most common form of inflammatory arthritis worldwide; however, no Canadian data on the disease burden of gout are available."1.46The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. ( Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rai, SK1
Aviña-Zubieta, JA1
McCormick, N1
De Vera, MA1
Shojania, K1
Sayre, EC1
Choi, HK1
Ryan, JR1
Bassett, DR1
Mikkelsen, WM1
Buckingham, RB1
Block, WD1
Sidiq, M1
Shakibai, A1
DiGaetano, R1
Liou, LL1
Gibson, T2
Kilbourn, K1
Horner, I1
Simmonds, HA1
Keller, C1
Wolfram, G1
Zöllner, N1
Grahame, R1
Bluestone, R1
Lewis, B1
Mervart, I1
Holländer, E1
Schwarczmann, P1

Trials

3 trials available for probenecid and Hyperlipidemias

ArticleYear
The metabolic spectrum of halofenate.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Blood Glucose; Cholesterol; Clinical Trials as Topic; Clofibrate; Creatine Kinase; Glycolates; Halof

1975
Effects of halofenate and probenecid on serum lipids and uric acid in hyperlipidemic, hyperuricemic adults.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3

    Topics: Adult; Aged; Body Weight; Cholesterol; Clinical Trials as Topic; Female; Glycolates; Halofenate; Hum

1977
[Treatment of hyperlipemia and hyperuricemia with 2-acetamidoethyl-(4-chlorophenyl)-(3-trifluoromethylphenoxy)-acetate (halofenate), a derivative of clofibrate].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:12

    Topics: Cholesterol; Clinical Trials as Topic; Female; Glycolates; Halofenate; Humans; Hyperlipidemias; Male

1976

Other Studies

5 other studies available for probenecid and Hyperlipidemias

ArticleYear
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012.
    Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4

    Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidit

2017
Mechanism and treatment of hypertriglyceridaemia in gout.
    Annals of the rheumatic diseases, 1979, Volume: 38, Issue:1

    Topics: Alcohol Drinking; Allopurinol; Cholesterol; Gout; Humans; Hyperlipidemias; Male; Middle Aged; Obesit

1979
Gout and hyperlipidaemia.
    Annals of the rheumatic diseases, 1974, Volume: 33, Issue:4

    Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Aspartate Aminotransferases; Body Height; Body Weight; C

1974
Hyperlipoproteinaemia in gout.
    Annals of the rheumatic diseases, 1971, Volume: 30, Issue:2

    Topics: Adult; Aged; Allopurinol; Blood Protein Disorders; Blood Protein Electrophoresis; Cholesterol; Gout;

1971
[Gout in advanced age].
    Munchener medizinische Wochenschrift (1950), 1968, Mar-15, Volume: 110, Issue:11

    Topics: Age Factors; Aged; Allopurinol; Bone and Bones; Cardiovascular Diseases; Colchicine; Female; Gout; H

1968