probenecid and HIV
probenecid has been researched along with HIV in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is the first randomized controlled trial to demonstrate a high efficacy of amoxicillin-based regimens for treating syphilis in patients with HIV infection, and the non-inferiority of low-dose amoxicillin compared with amoxicillin plus probenecid was not seen." | 9.69 | Combination of Amoxicillin 3000 mg and Probenecid Versus 1500 mg Amoxicillin Monotherapy for Treating Syphilis in Patients With Human Immunodeficiency Virus: An Open-Label, Randomized, Controlled, Non-Inferiority Trial. ( Ando, N; Aoki, T; Gatanaga, H; Hiramoto, S; Inamura, N; Kikuchi, Y; Mizushima, D; Nemoto, T; Oka, S; Omata, K; Shiojiri, D; Takano, M; Tanuma, J; Teruya, K; Uemura, H; Watanabe, K; Yanagawa, Y, 2023) |
| "This is the first randomized controlled trial to demonstrate a high efficacy of amoxicillin-based regimens for treating syphilis in patients with HIV infection, and the non-inferiority of low-dose amoxicillin compared with amoxicillin plus probenecid was not seen." | 5.69 | Combination of Amoxicillin 3000 mg and Probenecid Versus 1500 mg Amoxicillin Monotherapy for Treating Syphilis in Patients With Human Immunodeficiency Virus: An Open-Label, Randomized, Controlled, Non-Inferiority Trial. ( Ando, N; Aoki, T; Gatanaga, H; Hiramoto, S; Inamura, N; Kikuchi, Y; Mizushima, D; Nemoto, T; Oka, S; Omata, K; Shiojiri, D; Takano, M; Tanuma, J; Teruya, K; Uemura, H; Watanabe, K; Yanagawa, Y, 2023) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ando, N | 1 |
| Mizushima, D | 1 |
| Omata, K | 1 |
| Nemoto, T | 1 |
| Inamura, N | 1 |
| Hiramoto, S | 1 |
| Takano, M | 1 |
| Aoki, T | 1 |
| Watanabe, K | 1 |
| Uemura, H | 1 |
| Shiojiri, D | 1 |
| Yanagawa, Y | 1 |
| Tanuma, J | 1 |
| Teruya, K | 1 |
| Kikuchi, Y | 1 |
| Gatanaga, H | 1 |
| Oka, S | 1 |
| Speck, RR | 1 |
| Yu, XF | 1 |
| Hildreth, J | 1 |
| Flexner, C | 1 |
Trials
1 trial available for probenecid and HIV
| Article | Year |
|---|---|
Combination of Amoxicillin 3000 mg and Probenecid Versus 1500 mg Amoxicillin Monotherapy for Treating Syphilis in Patients With Human Immunodeficiency Virus: An Open-Label, Randomized, Controlled, Non-Inferiority Trial.
Topics: Amoxicillin; Anti-Bacterial Agents; Drug-Related Side Effects and Adverse Reactions; HIV; HIV Infect | 2023 |
Other Studies
1 other study available for probenecid and HIV
| Article | Year |
|---|---|
Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cells, Cultured; | 2002 |