Page last updated: 2024-11-03

probenecid and Gouty Arthritis

probenecid has been researched along with Gouty Arthritis in 22 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Research Excerpts

ExcerptRelevanceReference
"Low dose daily enteric coated aspirin does not significantly interfere with the uricosuric effects of probenecid in patients with gouty arthritis."9.09Effect of low dose daily aspirin on serum urate levels and urinary excretion in patients receiving probenecid for gouty arthritis. ( Alloway, J; Bryant, LR; Danaher, P; Harris, M, 2000)
"No significant increase was noted in acute gout flare severity or duration among GA patients treated with early aggressive control of hyperuricemia using probenecid plus colchicine."5.69Early urate-lowering therapy in gouty arthritis with acute flares: a double-blind placebo controlled clinical trial. ( Chen, HC; Wei, JC; Yang, DH, 2023)
"Low dose daily enteric coated aspirin does not significantly interfere with the uricosuric effects of probenecid in patients with gouty arthritis."5.09Effect of low dose daily aspirin on serum urate levels and urinary excretion in patients receiving probenecid for gouty arthritis. ( Alloway, J; Bryant, LR; Danaher, P; Harris, M, 2000)
" Allopurinol can be used for the prophylactic management of chronic hyperuricemia in patients with CKD, but the recommended decreased dosage may limit efficacy and serious hypersensitivity reactions may preclude its use."4.88Challenges associated with the management of gouty arthritis in patients with chronic kidney disease: a systematic review. ( Curiel, RV; Guzman, NJ, 2012)
"The characteristic phenomena of acute gouty arthritis are acute arthritis in a middle-aged male, associated with serum uric acid above 6 mg."3.63Diagnosis and treatment of gouty arthritis. ( TALBOTT, JH, 1953)
" On the basis of diet intervention, the observation group was treated with electroacupuncture at local points combined with blood-letting puncture and cupping, and the control group with oral administration of Probenecid."2.74[Observation on therapeutic effect of electroacupuncture plus blood-letting puncture and cupping combined with diet intervention for treatment of acute gouty arthritis]. ( Gao, Y; Li, W; Liu, J; Qu, XD; Wang, S; Zhao, QW; Zhu, LW, 2009)
"Gout and calcium pyrophosphate deposition disease are two common causes of inflammatory joint disease."2.43An update on the treatment options for gout and calcium pyrophosphate deposition. ( Choy, G, 2005)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199013 (59.09)18.7374
1990's3 (13.64)18.2507
2000's3 (13.64)29.6817
2010's2 (9.09)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Yang, DH1
Chen, HC1
Wei, JC1
Zhao, QW1
Liu, J1
Qu, XD1
Li, W1
Wang, S1
Gao, Y1
Zhu, LW1
Müller-Ladner, U1
Panzner, I1
Kriegsmann, J1
Lange, U1
Tausche, AK1
Curiel, RV1
Guzman, NJ1
TALBOTT, JH4
HUEBER, EF1
LUCKERBAUER, H1
MORAWETZ, F1
MARSON, FG1
LOCKIE, LM2
BISHOP, CW1
GAMP, A1
RICE, FA1
FRITZE, E1
MUELLER, HO1
BENE, P1
D ANGLEJEAN, G1
VELAYOS, EE1
SMYTH, CJ1
GUTMAN, AB1
YU, TF1
NORCROSS, BM1
BISHOP, C1
Choy, G1
Chazerain, P1
Ziza, JM1
Harris, M1
Bryant, LR1
Danaher, P1
Alloway, J1
McCarthy, GM1
Barthelemy, CR1
Veum, JA1
Wortmann, RL1
Nuki, G1
Watson, ML1
Williams, BC1
Simmonds, HA1
Wallace, RC1

Reviews

3 reviews available for probenecid and Gouty Arthritis

ArticleYear
[Gout - regardless of therapeutic options a "forgotten" disease].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:33

    Topics: Allopurinol; Arthritis, Gouty; Benzbromarone; Combined Modality Therapy; Cytokines; Europe; Febuxost

2011
Challenges associated with the management of gouty arthritis in patients with chronic kidney disease: a systematic review.
    Seminars in arthritis and rheumatism, 2012, Volume: 42, Issue:2

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Colchicine; Comorbidity; Con

2012
An update on the treatment options for gout and calcium pyrophosphate deposition.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:14

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Animals; Anti-Inflammatory Agents

2005

Trials

3 trials available for probenecid and Gouty Arthritis

ArticleYear
Early urate-lowering therapy in gouty arthritis with acute flares: a double-blind placebo controlled clinical trial.
    European journal of medical research, 2023, Jan-06, Volume: 28, Issue:1

    Topics: Arthritis, Gouty; Chronic Disease; Colchicine; Gout; Gout Suppressants; Humans; Probenecid; Symptom

2023
[Observation on therapeutic effect of electroacupuncture plus blood-letting puncture and cupping combined with diet intervention for treatment of acute gouty arthritis].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2009, Volume: 29, Issue:9

    Topics: Adult; Aged; Arthritis, Gouty; Bloodletting; Combined Modality Therapy; Electroacupuncture; Humans;

2009
Effect of low dose daily aspirin on serum urate levels and urinary excretion in patients receiving probenecid for gouty arthritis.
    The Journal of rheumatology, 2000, Volume: 27, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Cross-O

2000

Other Studies

16 other studies available for probenecid and Gouty Arthritis

ArticleYear
Diagnosis and treatment of gouty arthritis.
    California medicine, 1953, Volume: 79, Issue:3

    Topics: Arthritis; Arthritis, Gouty; Colchicine; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid;

1953
[Therapy of chronic gout with benemid and cortisone].
    Klinische Wochenschrift, 1954, Feb-01, Volume: 32, Issue:5-6

    Topics: Arthritis, Gouty; Chronic Disease; Cortisone; Gout; Probenecid

1954
Sodium salicylate and probenecid in the treatment of chronic gout; assessment of their relative effects in lowering serum uric acid levels.
    Annals of the rheumatic diseases, 1954, Volume: 13, Issue:3

    Topics: Arthritis, Gouty; Blood; Chronic Disease; Gout; Humans; Probenecid; Salicylates; Sodium Salicylate;

1954
[Gout and gouty arthritis].
    Arizona medicine, 1957, Volume: 14, Issue:12

    Topics: Arthritis, Gouty; Gout; Humans; Phenylbutazone; Probenecid

1957
[Medical treatment of chronic gout].
    Arztliche Wochenschrift, 1957, Aug-30, Volume: 12, Issue:35-36

    Topics: Arthritis, Gouty; Chronic Disease; Gout; Probenecid; Sulfanilamide; Sulfanilamides; Sulfonamides

1957
Selected aspects of acute and chronic gouty arthritis; an internist's interpretation of an orthopaedist's experiences with gout and gouty arthritis.
    The Journal of bone and joint surgery. American volume, 1958, Volume: 40-A, Issue:5

    Topics: Arthritis, Gouty; Chronic Disease; Colchicine; Gout; Humans; Orthopedics; Probenecid

1958
Probenecid (benemid) in the treatment of gout and gouty arthritis.
    Minnesota medicine, 1959, Volume: 42, Issue:3

    Topics: Arthritis, Gouty; Gout; Humans; Minnesota; Probenecid

1959
[On probenecid treatment of chronic gout. Report of a severe complication of treatment].
    Deutsche medizinische Wochenschrift (1946), 1962, Jan-12, Volume: 87

    Topics: Arthritis, Gouty; Chronic Disease; Gout; Humans; Probenecid; Uremia

1962
[URICO-ELIMINATOR TREATMENT OF CHRONIC GOUT].
    France Medecine, 1963, Volume: 26

    Topics: Arthritis, Gouty; Gout; Phenylbutazone; Probenecid; Pyrazoles; Salicylates; Uricosuric Agents; Zoxaz

1963
[ASSESSMENT OF 172 CASES OF CHRONIC GOUT TREATED BY PROBENECID FOR 10 YEARS].
    France Medecine, 1963, Volume: 26

    Topics: Acute Kidney Injury; Arthritis, Gouty; Gout; Humans; Kidney Calculi; Probenecid; Renal Insufficiency

1963
URATE DIURETIC THERAPY IN CHRONIC GOUT; A COMPARATIVE STUDY OF PROBENECID AND SULFINPYRAZONE.
    Archives of internal medicine, 1965, Volume: 116

    Topics: Arthritis, Gouty; Biomedical Research; Blood; Diuretics; Drug Therapy; Gout; Humans; Kidney Calculi;

1965
Benemid (p-di-n-propylsulfamyl)-benzoic acid) as uricosuric agent in chronic gouty arthritis.
    Transactions of the Association of American Physicians, 1951, Volume: 64

    Topics: Arthritis, Gouty; Benzoic Acid; Body Fluids; Chronic Disease; Gout; Probenecid; Uric Acid; Uricosuri

1951
Effect of benemid in gouty arthritis.
    Annals of the rheumatic diseases, 1951, Volume: 10, Issue:4

    Topics: Aged; Arthritis, Gouty; Gout; Humans; Probenecid

1951
[Gout: physiopathology, diagnosis, course, treatment].
    La Revue du praticien, 1998, Sep-01, Volume: 48, Issue:13

    Topics: Adult; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Diagnosis, Differential; Female; Gout; Go

1998
Influence of antihyperuricemic therapy on the clinical and radiographic progression of gout.
    Arthritis and rheumatism, 1991, Volume: 34, Issue:12

    Topics: Aged; Aged, 80 and over; Allopurinol; Arthritis, Gouty; Humans; Middle Aged; Probenecid; Radiography

1991
Congenital chloride losing enteropathy associated with tophaceous gouty arthritis.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Adult; Alkalosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Blood Pressure; Captopr

1991