probenecid has been researched along with Gout in 272 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the pharmacokinetic and pharmacodynamic interaction between probenecid and oxypurinol (the active metabolite of allopurinol) in patients with gout." | 9.15 | Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout. ( Day, RO; Graham, GG; McLachlan, AJ; Stocker, SL; Williams, KM, 2011) |
| "To investigate the efficacy and tolerability of allopurinol as the first-choice antihyperuricaemic treatment for gout, and compare the efficacy and tolerability of benzbromarone and probenecid as second-choice treatment." | 9.14 | Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. ( Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN, 2009) |
| "To assess the efficacy and safety of allopurinol compared with placebo and other urate-lowering therapies for treating chronic gout." | 8.90 | Allopurinol for chronic gout. ( Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R, 2014) |
| "The authors conducted a cohort study to examine comparative CV safety of the 2 gout treatments-probenecid and allopurinol-in patients with gout." | 7.88 | Cardiovascular Risks of Probenecid Versus Allopurinol in Older Patients With Gout. ( Desai, RJ; Kang, EH; Kim, SC; Liu, J; Neogi, T; Solomon, DH; Zhang, M, 2018) |
| "Probenecid has moderate efficacy as ULT in clinical management of patients with complex gout who have a lack of efficacy or intolerance to allopurinol." | 7.79 | Efficacy and tolerability of probenecid as urate-lowering therapy in gout; clinical experience in high-prevalence population. ( Dalbeth, N; Gow, PJ; Pui, K, 2013) |
| " A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout." | 7.78 | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid. ( Asmahan, MI; Hilmi, BA; Rosman, A, 2012) |
| "In conclusion, this first established pharmacokinetic model provides a tool to achieve target oxypurinol plasma concentrations, thereby optimizing the effectiveness and safety of allopurinol therapy in gouty patients with various degrees of renal impairment." | 7.78 | The pharmacokinetics of oxypurinol in people with gout. ( Day, RO; Graham, GG; Kirkpatrick, CM; McLachlan, AJ; Savic, RM; Stocker, SL; Williams, KM, 2012) |
| "The use of long-term allopurinol therapy in patients with gout was evaluated." | 7.67 | Evaluation of allopurinol use in patients with gout. ( Carmichael, JM; Zell, SC, 1989) |
"Benzbromarone is a very effective antihyperuricemic drug with 91% success in attainment of target sUr levels | 6.73 | Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients. ( Brouwers, JR; Houtman, PM; Jansen, TL; Reinders, MK; van Roon, EN, 2007) | |
| "No significant increase was noted in acute gout flare severity or duration among GA patients treated with early aggressive control of hyperuricemia using probenecid plus colchicine." | 5.69 | Early urate-lowering therapy in gouty arthritis with acute flares: a double-blind placebo controlled clinical trial. ( Chen, HC; Wei, JC; Yang, DH, 2023) |
| "This network meta-analysis demonstrated an important absolute benefit of dotinurad 4 mg once daily to achieve target serum uric acid and low risk of adverse events for drug treatment of gout or hyperuricemia patients." | 5.41 | Comparative efficacy and safety of uricosuric agents in the treatment of gout or hyperuricemia: a systematic review and network meta-analysis. ( Chen, LR; Guo, Y; He, GH; Jiang, FF; Li, YJ; Qian, K; Wang, P; Yang, M; Yang, ZL; Yin, SJ, 2023) |
| "To investigate the pharmacokinetic and pharmacodynamic interaction between probenecid and oxypurinol (the active metabolite of allopurinol) in patients with gout." | 5.15 | Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout. ( Day, RO; Graham, GG; McLachlan, AJ; Stocker, SL; Williams, KM, 2011) |
| "To investigate the efficacy and tolerability of allopurinol as the first-choice antihyperuricaemic treatment for gout, and compare the efficacy and tolerability of benzbromarone and probenecid as second-choice treatment." | 5.14 | Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. ( Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN, 2009) |
| " Arhalofenate also acts by blocking URAT-1; however, it also blocks the NALP-3 inflammasome providing gout-specific anti-inflammatory effect." | 4.98 | New urate-lowing therapies. ( Abhishek, A, 2018) |
| "Over the last 70 years, pharmacotherapy in gout with urate-lowering drugs has consisted of four drugs only: In 1952, a mild uricosuric probenecid became available, the xanthine oxidase inhibitor Allopurinol in 1964, and the latter became the most frequently used urate-lowering drug worldwide; in the Eurozone, the uricosuric benzbromarone was welcomed in 1977." | 4.98 | International position paper on the appropriate use of uricosurics with the introduction of lesinurad. ( Jansen, TL; Perez-Ruiz, F; Richette, P; Tausche, AK, 2018) |
| " Better understanding of the transporters URAT1 and ABCG2 in particular would appear to provide opportunities for more selective, better tolerated agents to increase the renal clearance of uric acid and thereby control hyperuricemia." | 4.90 | Uricosuric drugs: the once and future therapy for hyperuricemia? ( Bach, MH; Simkin, PA, 2014) |
| "To assess the efficacy and safety of allopurinol compared with placebo and other urate-lowering therapies for treating chronic gout." | 4.90 | Allopurinol for chronic gout. ( Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R, 2014) |
| "We considered all randomised controlled trials (RCTs) or quasi-randomised controlled trials (controlled clinical trials (CCTs)) that compared uricosuric medications (benzbromarone, probenecid or sulphinpyrazone) alone or in combination with another therapy (placebo or other active uric acid-lowering medication, or non-pharmacological treatment) in adults with chronic gout for inclusion." | 4.90 | Uricosuric medications for chronic gout. ( Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R, 2014) |
| " Interestingly, throughout the last 60 years, there have been a host of apparently unrelated studies using probenecid in the clinical and basic research arena, including its potential use in the diagnosis and treatment of depression and its use to prevent fura-2 leakage in calcium transient studies." | 4.88 | The history and future of probenecid. ( Koch, SE; Robbins, N; Rubinstein, J; Tranter, M, 2012) |
| " Chronic hyperuricemia (uric acid serum levels >6." | 4.86 | Crystal arthropathies: recognizing and treating "the gouch". ( Quillen, DM, 2010) |
| "Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism." | 4.77 | Hyperuricemia and gout. ( German, DC; Holmes, EW, 1986) |
| " Injectable gold compounds and penicillamine are not contraindicated in the elderly, because they are just as efficacious as in younger persons for the treatment of rheumatoid arthritis." | 4.76 | Problems of antiarthritic therapy in the elderly. ( Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF, 1984) |
| "The authors conducted a cohort study to examine comparative CV safety of the 2 gout treatments-probenecid and allopurinol-in patients with gout." | 3.88 | Cardiovascular Risks of Probenecid Versus Allopurinol in Older Patients With Gout. ( Desai, RJ; Kang, EH; Kim, SC; Liu, J; Neogi, T; Solomon, DH; Zhang, M, 2018) |
| "Probenecid has moderate efficacy as ULT in clinical management of patients with complex gout who have a lack of efficacy or intolerance to allopurinol." | 3.79 | Efficacy and tolerability of probenecid as urate-lowering therapy in gout; clinical experience in high-prevalence population. ( Dalbeth, N; Gow, PJ; Pui, K, 2013) |
| " A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout." | 3.78 | Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid. ( Asmahan, MI; Hilmi, BA; Rosman, A, 2012) |
| "In conclusion, this first established pharmacokinetic model provides a tool to achieve target oxypurinol plasma concentrations, thereby optimizing the effectiveness and safety of allopurinol therapy in gouty patients with various degrees of renal impairment." | 3.78 | The pharmacokinetics of oxypurinol in people with gout. ( Day, RO; Graham, GG; Kirkpatrick, CM; McLachlan, AJ; Savic, RM; Stocker, SL; Williams, KM, 2012) |
| " Allopurinol is more frequently used than uricosuric agents such as probenecid, and toxicity may be largely avoided by tailoring dosage schedules according to renal function." | 3.77 | Risks and benefits of drugs used in the management and prevention of gout. ( Conaghan, PG; Day, RO, 1994) |
| "We identified persons using two integrated delivery systems aged 18 years or older with a diagnosis of gout who initiated use of allopurinol, probenecid or sulfinpyrazone from 1 January 2000 to 30 June 2006." | 3.75 | Adherence with urate-lowering therapies for the treatment of gout. ( Andrade, SE; Briesacher, BA; Fouayzi, H; Harrold, LR; Ockene, IS; Raebel, MA; Yood, RA, 2009) |
| " During episodes of renal insufficiency, appropriate dose reduction/discontinuation of probenecid was done in 24/31 episodes (77%) and of colchicine in 36/52 episodes (69%)." | 3.75 | Opportunities for improving medication use and monitoring in gout. ( Asch, SM; Hodges, JS; Singh, JA, 2009) |
| "We report a patient who, while receiving probenecid and colchicine for acute gouty arthritis, developed severe hemolytic anemia in association with a generalized rash." | 3.67 | Probenecid induced immune hemolytic anemia. ( Buck, S; Kickler, TS; Ness, P; Shirey, RS; Sholar, PW, 1986) |
| "The use of long-term allopurinol therapy in patients with gout was evaluated." | 3.67 | Evaluation of allopurinol use in patients with gout. ( Carmichael, JM; Zell, SC, 1989) |
| " Drugs used for hyperuricemia and gout such as colchicine, allopurinol, probenecid, and sulphinpyrazone have not been implicated in affecting exercise performance." | 3.66 | Effects of exercise performance on drugs used in musculoskeletal disorders. ( Day, RO, 1981) |
| "For control of acute episodes of gout, administration of a full course of colchicine is the preferred method of therapy." | 3.66 | Treating gout: successful methods of prevention and control. ( Talbott, JH, 1978) |
| " The drug is particularly useful in patients with chronic gouty arthritis and tophi, either refractory or allergic to probenecid, sulfinpyrazone, or allopurinol." | 3.65 | Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. ( Yu, TF, 1976) |
| "The characteristic phenomena of acute gouty arthritis are acute arthritis in a middle-aged male, associated with serum uric acid above 6 mg." | 3.63 | Diagnosis and treatment of gouty arthritis. ( TALBOTT, JH, 1953) |
"Benzbromarone is a very effective antihyperuricemic drug with 91% success in attainment of target sUr levels | 2.73 | Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients. ( Brouwers, JR; Houtman, PM; Jansen, TL; Reinders, MK; van Roon, EN, 2007) | |
| " The use of allopurinol has been researched extensively and newer strategies for safer effective dosing are now recommended." | 2.58 | Gout - An update of aetiology, genetics, co-morbidities and management. ( Robinson, PC, 2018) |
| "Although gout is one of the most common forms of inflammatory arthritis, it has been relatively neglected until recently." | 2.55 | Major unanswered questions in the clinical gout field. ( Stamp, LK, 2017) |
| " Studies have identified the safe and effective dosing strategies for 'old' drugs such as allopurinol and colchicine." | 2.52 | Advances in pharmacotherapy for the treatment of gout. ( Dalbeth, N; Robinson, PC, 2015) |
| "Febuxostat is a new xanthine oxidase inhibitor, which will be available for the treatment of refractory gout in the near future." | 2.46 | [The clinical picture of gout is changing]. ( Julkunen, H; Konttinen, YT, 2010) |
| "Gout and calcium pyrophosphate deposition disease are two common causes of inflammatory joint disease." | 2.43 | An update on the treatment options for gout and calcium pyrophosphate deposition. ( Choy, G, 2005) |
| "Hyperuricemia is a central risk factor for gout and increases the risk for other chronic diseases, including cardiometabolic disease, kidney disease, and hypertension." | 1.56 | High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout. ( Dai, S; Guo, Y; Hong, F; Li, L; Liu, G; Pan, S; Qiao, X; Wang, J; Xie, X; Xu, P; Xue, T; Zhai, Y; Zheng, A, 2020) |
| "Gout has significant impact on the quality of life with over-utilisation of health resources." | 1.56 | Burden and management of gout in a multi-ethnic Asian cohort. ( Cheung, PP; Chua, CKT; Lim, AYN; Santosa, A; Teng, GG, 2020) |
| "Hyperuricemia was defined as having a serum urate level of >7." | 1.51 | Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007-2016. ( Chen-Xu, M; Choi, HK; Pillinger, MH; Rai, SK; Yokose, C, 2019) |
| " His uric acid was 11 mg/dL despite maximal dosing of febuxostat." | 1.48 | Effective uric acid reduction with probenecid and febuxostat in a patient with chronic kidney disease. ( Case, R; Jester, G; Wentworth, B, 2018) |
| "Gout is increasingly recognized as the most common form of inflammatory arthritis worldwide; however, no Canadian data on the disease burden of gout are available." | 1.46 | The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. ( Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K, 2017) |
| "Patients with gout have comorbidities, but the impact of these comorbidities on treatment has not been studied." | 1.37 | Prevalence of contraindications and prescription of pharmacologic therapies for gout. ( Crittenden, DB; Fisher, MC; Goldfarb, DS; Keenan, RT; Krasnokutsky, S; Lee, KH; O'Brien, WR; Oh, C; Pillinger, MH, 2011) |
| "The management of gout has four phases: control of inflammation, diagnostic evaluation, education of the patient, and treatment for the hyperuricemia." | 1.26 | Management of gout. ( Simkin, PA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 211 (77.57) | 18.7374 |
| 1990's | 10 (3.68) | 18.2507 |
| 2000's | 13 (4.78) | 29.6817 |
| 2010's | 33 (12.13) | 24.3611 |
| 2020's | 5 (1.84) | 2.80 |
| Authors | Studies |
|---|---|
| Ichida, K | 1 |
| Hosoyamada, M | 1 |
| Kimura, H | 1 |
| Takeda, M | 1 |
| Utsunomiya, Y | 1 |
| Hosoya, T | 1 |
| Endou, H | 1 |
| Li, YJ | 1 |
| Chen, LR | 1 |
| Yang, ZL | 1 |
| Wang, P | 1 |
| Jiang, FF | 1 |
| Guo, Y | 2 |
| Qian, K | 1 |
| Yang, M | 1 |
| Yin, SJ | 1 |
| He, GH | 1 |
| Yang, DH | 1 |
| Chen, HC | 1 |
| Wei, JC | 1 |
| Chua, CKT | 1 |
| Cheung, PP | 1 |
| Santosa, A | 1 |
| Lim, AYN | 1 |
| Teng, GG | 1 |
| Hong, F | 1 |
| Zheng, A | 1 |
| Xu, P | 1 |
| Wang, J | 1 |
| Xue, T | 1 |
| Dai, S | 1 |
| Pan, S | 1 |
| Xie, X | 1 |
| Li, L | 1 |
| Qiao, X | 1 |
| Liu, G | 1 |
| Zhai, Y | 1 |
| Kim, SC | 3 |
| Neogi, T | 2 |
| Kim, E | 1 |
| Lii, J | 1 |
| Desai, RJ | 2 |
| Abhishek, A | 1 |
| Case, R | 1 |
| Wentworth, B | 1 |
| Jester, G | 1 |
| Givertz, MM | 1 |
| Kang, EH | 2 |
| Liu, J | 1 |
| Zhang, M | 1 |
| Solomon, DH | 2 |
| Jansen, TL | 4 |
| Perez-Ruiz, F | 2 |
| Tausche, AK | 2 |
| Richette, P | 2 |
| Robinson, PC | 2 |
| Chen-Xu, M | 1 |
| Yokose, C | 1 |
| Rai, SK | 2 |
| Pillinger, MH | 2 |
| Choi, HK | 2 |
| Pui, K | 1 |
| Gow, PJ | 1 |
| Dalbeth, N | 2 |
| Conway, R | 2 |
| Bach, MH | 1 |
| Simkin, PA | 3 |
| Doherty, M | 1 |
| Nuki, G | 1 |
| Pascual, E | 1 |
| Punzi, L | 1 |
| So, AK | 1 |
| Bardin, T | 1 |
| Seth, R | 2 |
| Kydd, AS | 2 |
| Buchbinder, R | 2 |
| Bombardier, C | 2 |
| Edwards, CJ | 2 |
| Ahmed, MU | 1 |
| Bennett, DJ | 1 |
| Hsieh, TC | 1 |
| Doonan, BB | 1 |
| Ahmed, S | 1 |
| Wu, JM | 1 |
| Stamp, LK | 1 |
| Aviña-Zubieta, JA | 1 |
| McCormick, N | 1 |
| De Vera, MA | 1 |
| Shojania, K | 1 |
| Sayre, EC | 1 |
| Corbett, EJM | 1 |
| Pentony, P | 1 |
| McGill, NW | 1 |
| Singh, JA | 1 |
| Hodges, JS | 1 |
| Asch, SM | 1 |
| Harrold, LR | 1 |
| Andrade, SE | 1 |
| Briesacher, BA | 1 |
| Raebel, MA | 1 |
| Fouayzi, H | 1 |
| Yood, RA | 1 |
| Ockene, IS | 1 |
| Thiele, RG | 1 |
| Schlesinger, N | 1 |
| Ali, S | 1 |
| Lally, EV | 1 |
| Simon, HB | 1 |
| Julkunen, H | 1 |
| Konttinen, YT | 1 |
| Quillen, DM | 1 |
| Taniguchi, A | 1 |
| Stocker, SL | 2 |
| Graham, GG | 2 |
| McLachlan, AJ | 2 |
| Williams, KM | 2 |
| Day, RO | 4 |
| Keenan, RT | 1 |
| O'Brien, WR | 1 |
| Lee, KH | 1 |
| Crittenden, DB | 1 |
| Fisher, MC | 1 |
| Goldfarb, DS | 1 |
| Krasnokutsky, S | 1 |
| Oh, C | 1 |
| Müller-Ladner, U | 1 |
| Panzner, I | 1 |
| Kriegsmann, J | 1 |
| Lange, U | 1 |
| Robbins, N | 1 |
| Koch, SE | 1 |
| Tranter, M | 1 |
| Rubinstein, J | 1 |
| Adenwalla, HN | 1 |
| O'Connor, CR | 1 |
| Lipworth, W | 1 |
| Kerridge, I | 1 |
| Brett, J | 1 |
| Day, R | 1 |
| Savic, RM | 1 |
| Kirkpatrick, CM | 1 |
| Hilmi, BA | 1 |
| Asmahan, MI | 1 |
| Rosman, A | 1 |
| Coughlan, RJ | 1 |
| Carey, JJ | 1 |
| Yamanaka, H | 2 |
| TALBOTT, JH | 11 |
| LOCKIE, LM | 4 |
| NORCROSS, BM | 3 |
| BISHOP, C | 4 |
| HOFFMAN, WS | 3 |
| BUCHT, H | 1 |
| HUEBER, EF | 1 |
| LUCKERBAUER, H | 1 |
| MORAWETZ, F | 1 |
| MASON, RM | 2 |
| DAVID-CHAUSSE, J | 1 |
| DAVID-CHAUSSE, F | 1 |
| BOGER, WP | 2 |
| SMITH, RT | 1 |
| MARSON, FG | 2 |
| GUTMAN, AB | 12 |
| YU, TF | 10 |
| RANDOLPH, V | 1 |
| STRICKLAND, SC | 1 |
| BARTELS, EC | 5 |
| HOPPE, D | 1 |
| PHILLIPS, RW | 1 |
| GAUTIER, B | 1 |
| GJORUP, S | 1 |
| POULSEN, H | 1 |
| MINARELLI, A | 1 |
| SMYTH, CJ | 2 |
| HUFFMAN, ER | 1 |
| WILSON, GM | 1 |
| BAUER, W | 2 |
| SINGH, MM | 2 |
| SARTORELLI, E | 1 |
| SBERTOLI, C | 1 |
| BISHOP, CW | 1 |
| STILLMAN, JS | 1 |
| GAMP, A | 1 |
| SVENDSEN, HM | 1 |
| LACAPERE, J | 1 |
| RICE, FA | 1 |
| MATOSSIAN, GS | 1 |
| FERRIS, TF | 1 |
| MORGAN, WS | 1 |
| LEVITIN, H | 1 |
| FRITZE, E | 1 |
| MUELLER, HO | 1 |
| THOMPSON, GR | 2 |
| DUFF, IF | 1 |
| ROBINSON, WD | 1 |
| MIKKELSEN, WM | 2 |
| GALINDEZ, H | 1 |
| OSHIMA, Y | 2 |
| YOSHIMURA, T | 1 |
| SATO, T | 1 |
| KAGAMI, T | 1 |
| AKAOKA, I | 2 |
| NISHIZAWA, T | 1 |
| FREYBERG, RH | 1 |
| HOLLANDER, E | 2 |
| ATTALI, P | 1 |
| RYCKEWAERT, A | 1 |
| D'ANGLEJAN, G | 1 |
| DELBARRE, F | 2 |
| AUSCHER, C | 2 |
| RICHET, F | 1 |
| KNAPP, HA | 1 |
| NEWCOMBE, DS | 1 |
| COHEN, AS | 1 |
| BENE, P | 1 |
| D ANGLEJEAN, G | 1 |
| BATT, RE | 1 |
| CIRKSENA, WJ | 1 |
| LEBHERZ, TB | 1 |
| CHETRICK, A | 1 |
| DENKO, CW | 1 |
| STERN, FH | 1 |
| BUBLEWSKA, B | 1 |
| BAKER, OA | 1 |
| WILLIAMSON, CI | 1 |
| BEETHAM, WP | 1 |
| SCOTT, JT | 5 |
| DIXON, AS | 1 |
| BYWATERS, EG | 1 |
| OGRYZLO, MA | 1 |
| CARCASSONNE, Y | 1 |
| CARVER, M | 1 |
| RIVERA, JV | 2 |
| TREADWELL, B | 1 |
| REAH, TG | 1 |
| KUZELL, WC | 1 |
| GLOVER, RP | 1 |
| GIBBS, JO | 1 |
| BLAU, RA | 1 |
| HALL, AP | 1 |
| HOLLOWAY, VP | 1 |
| LIPSON, RL | 1 |
| SLOCUMB, CH | 1 |
| RIZZUTO, VJ | 1 |
| INGLESBY, TV | 1 |
| GRACE, WJ | 1 |
| GOLDFINGER, S | 1 |
| KLINENBERG, JR | 3 |
| SEEGMILLER, JE | 3 |
| RINGOIR, S | 1 |
| VELAYOS, EE | 1 |
| HILLECKE, NA | 1 |
| MCCORMICK, EW | 1 |
| FROST, H | 1 |
| PASCALE, LR | 2 |
| DUBIN, A | 2 |
| BRONSKY, D | 1 |
| GAUCHER, M | 1 |
| SOUPLET, P | 1 |
| NOELLE, H | 1 |
| RAND, R | 1 |
| SIROTA, JH | 1 |
| Choy, G | 1 |
| Moreland, LW | 1 |
| Reinders, MK | 2 |
| van Roon, EN | 2 |
| Houtman, PM | 1 |
| Brouwers, JR | 2 |
| Izzedine, H | 1 |
| Brocheriou, I | 1 |
| Becart, J | 1 |
| Deray, G | 1 |
| Avorn, J | 1 |
| Levin, R | 1 |
| Brookhart, MA | 1 |
| Delsing, J | 1 |
| Griep, EN | 1 |
| Hoekstra, M | 1 |
| van de Laar, MA | 1 |
| Maclachlan, MJ | 1 |
| Rodnan, GP | 2 |
| Jakovcic, S | 1 |
| Sorensen, LB | 1 |
| Podevin, R | 1 |
| Paillard, F | 1 |
| Amiel, C | 1 |
| Richet, G | 1 |
| Mugler, A | 1 |
| Gaines, LM | 1 |
| Wisner, DE | 1 |
| Reginato, A | 1 |
| Paul, H | 1 |
| Schumacher, HR | 2 |
| Brooks, PM | 1 |
| Kean, WF | 1 |
| Kassam, Y | 1 |
| Buchanan, WW | 1 |
| Puig, JG | 2 |
| Mateos, F | 2 |
| Muñoz, A | 1 |
| Gaspar, G | 1 |
| Ramos, T | 1 |
| Gijón Baños, J | 1 |
| Weinberger, A | 1 |
| Schindel, B | 1 |
| Liberman, UA | 1 |
| Pinkhas, J | 1 |
| Sperling, O | 1 |
| Helliwell, M | 1 |
| Crisp, AJ | 1 |
| Grahame, R | 2 |
| Baiatova, KV | 1 |
| Muñez-Sanz, A | 1 |
| Garcia-Puig, J | 1 |
| Obel, AO | 1 |
| Bollet, AJ | 1 |
| Gut, JP | 1 |
| Kaneko, K | 1 |
| Fujimori, S | 1 |
| Conaghan, PG | 1 |
| Ferraz, MB | 1 |
| Hisatome, I | 1 |
| Kosaka, H | 1 |
| Ohtahara, K | 1 |
| Tsuboi, M | 1 |
| Manabe, I | 1 |
| Ohtahara, A | 1 |
| Sawaguchi, M | 1 |
| Igawa, O | 1 |
| Tanaka, Y | 1 |
| Fujimoto, Y | 1 |
| Yoshida, A | 1 |
| Takeda, A | 1 |
| Shigemasa, C | 1 |
| Toda, K | 1 |
| Goriki, K | 1 |
| Ochiai, M | 1 |
| Tokunou, H | 1 |
| Uehara, S | 1 |
| Takahashi, H | 1 |
| Okusaki, K | 1 |
| Lhotta, K | 1 |
| Gruber, J | 1 |
| Sgonc, R | 1 |
| Fend, F | 1 |
| König, P | 1 |
| Decaux, G | 1 |
| Soupart, A | 1 |
| Musch, W | 1 |
| Hannotier, P | 1 |
| Prospert, F | 1 |
| Chazerain, P | 1 |
| Ziza, JM | 1 |
| Gröbner, W | 1 |
| Walter-Sack, I | 1 |
| Musil, J | 1 |
| Boss, GR | 1 |
| Campanacci, L | 1 |
| Pallalardo, A | 1 |
| Gancitano, A | 1 |
| Schräpler, P | 1 |
| Schulz, E | 1 |
| Kleinschmidt, A | 1 |
| Emmerson, BT | 1 |
| Peitzman, SJ | 1 |
| Fernandez, PC | 1 |
| Bodison, W | 1 |
| Ellis, I | 1 |
| Gibson, T | 2 |
| Kilbourn, K | 1 |
| Horner, I | 1 |
| Simmonds, HA | 1 |
| Bayliss, RI | 1 |
| McCarty, DJ | 2 |
| Kawenoki-Minc, E | 7 |
| Eyman, E | 4 |
| Abgarowicz, T | 1 |
| Brzozowska-Jurkowska, M | 1 |
| Weryńska-Przybylska, J | 4 |
| Gordon, GV | 1 |
| Mikanagi, K | 2 |
| Nishioka, K | 3 |
| Alvsaker, JO | 1 |
| Brzozowska, AM | 1 |
| Horwitz, D | 1 |
| Thorgeirsson, SS | 1 |
| Mitchell, JR | 1 |
| Kelley, WN | 3 |
| Gottlieb, N | 1 |
| Grendelmeier, P | 1 |
| Rodriguez, E | 1 |
| O'Duffy, JD | 1 |
| Hunder, GG | 1 |
| Kelly, PJ | 1 |
| Nicholson, G | 1 |
| Leo, W | 1 |
| Brzozowska, M | 1 |
| Lang, GA | 1 |
| Wolfe, F | 1 |
| Cathey, MA | 1 |
| Zell, SC | 1 |
| Carmichael, JM | 1 |
| Smith, CR | 1 |
| Patrone, NA | 1 |
| German, DC | 1 |
| Holmes, EW | 1 |
| Garyfallos, A | 1 |
| Magoula, I | 1 |
| Tsapas, G | 1 |
| Kickler, TS | 1 |
| Buck, S | 1 |
| Ness, P | 1 |
| Shirey, RS | 1 |
| Sholar, PW | 1 |
| Mateos, FA | 1 |
| Jimenez, ML | 1 |
| Herrero, EH | 1 |
| Arnalich, FF | 1 |
| Vazquez, JJ | 1 |
| Darlington, LG | 1 |
| García Puig, J | 1 |
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| López Jiménez, M | 1 |
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| Zöllner, N | 1 |
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| Freeman, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-12-01 | Not yet recruiting | ||
| ACTH vs Betamethasone for the Treatment of Acute Gout in Hospitalized Patients: A Randomized, Open Label, Comparative Study[NCT04306653] | 60 participants (Anticipated) | Interventional | 2018-01-05 | Recruiting | |||
| Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal in People With Chronic Pain Undergoing Voluntary Opioid Tapering: a Pilot Study[NCT04939623] | Phase 2 | 40 participants (Anticipated) | Interventional | 2023-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
40 reviews available for probenecid and Gout
| Article | Year |
|---|---|
Comparative efficacy and safety of uricosuric agents in the treatment of gout or hyperuricemia: a systematic review and network meta-analysis.
Topics: Gout; Gout Suppressants; Humans; Hyperuricemia; Network Meta-Analysis; Probenecid; Randomized Contro | 2023 |
New urate-lowing therapies.
Topics: Acetamides; Drug Interactions; Enzyme Inhibitors; Gout; Gout Suppressants; Humans; Phenylacetates; P | 2018 |
International position paper on the appropriate use of uricosurics with the introduction of lesinurad.
Topics: Benzbromarone; Europe; Febuxostat; Gout; Humans; International Cooperation; Practice Guidelines as T | 2018 |
Gout - An update of aetiology, genetics, co-morbidities and management.
Topics: Allopurinol; Chronic Disease; Comorbidity; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperu | 2018 |
Cardiovascular Safety of Urate Lowering Therapies.
Topics: Allopurinol; Cardiovascular Diseases; Endothelium; Febuxostat; Gout; Gout Suppressants; Heart Failur | 2019 |
Uricosuric drugs: the once and future therapy for hyperuricemia?
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Dis | 2014 |
Improving cardiovascular and renal outcomes in gout: what should we target?
Topics: Allopurinol; Cardiovascular Diseases; Colchicine; Diabetes Mellitus, Type 2; Disease Management; Gou | 2014 |
Allopurinol for chronic gout.
Topics: Allopurinol; Benzbromarone; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans | 2014 |
Uricosuric medications for chronic gout.
Topics: Adult; Aged; Allopurinol; Benzbromarone; Chronic Disease; Controlled Clinical Trials as Topic; Femal | 2014 |
Advances in pharmacotherapy for the treatment of gout.
Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclona | 2015 |
Repositioning of drugs using open-access data portal DTome: A test case with probenecid (Review).
Topics: Adjuvants, Pharmaceutic; Animals; Antineoplastic Agents; Antiviral Agents; Databases, Pharmaceutical | 2016 |
Major unanswered questions in the clinical gout field.
Topics: Allopurinol; Benzbromarone; Colchicine; Disease Progression; Febuxostat; Gout; Gout Suppressants; Hu | 2017 |
Treatment failure gout.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Gout; Gout Suppressants; Humans; P | 2009 |
[The clinical picture of gout is changing].
Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseas | 2010 |
Crystal arthropathies: recognizing and treating "the gouch".
Topics: Allopurinol; Antimetabolites; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Huma | 2010 |
[Treatment of hyperuricemia and gout based on the guideline for the management of hyperuricemia and gout].
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Glucocorticoids; Go | 2010 |
[Gout - regardless of therapeutic options a "forgotten" disease].
Topics: Allopurinol; Arthritis, Gouty; Benzbromarone; Combined Modality Therapy; Cytokines; Europe; Febuxost | 2011 |
The history and future of probenecid.
Topics: Animals; Anti-Bacterial Agents; Depression; Fura-2; Gout; Humans; Probenecid; TRPV Cation Channels; | 2012 |
[Drug therapy for idiopathic hyperuricemia--introduction, dose, and side effects].
Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Enzyme Inhibitors; Gout; Humans; Hyperuricemia; Kidney | 2003 |
An update on the treatment options for gout and calcium pyrophosphate deposition.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Animals; Anti-Inflammatory Agents | 2005 |
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory | 1984 |
Treatment of the gout and other forms of crystal-induced arthritis.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Go | 1982 |
Risks and benefits of drugs used in the management and prevention of gout.
Topics: Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Doubl | 1994 |
An evidence based appraisal of the management of nontophaceous interval gout.
Topics: Clinical Trials as Topic; Colchicine; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Pr | 1995 |
Hyperuricemia and gout. Classification, complications and management.
Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human | 1979 |
[Gout. Diagnosis--pathogenesis--therapy].
Topics: Allopurinol; Balneology; Benzofurans; Crystallization; Diagnosis, Differential; Exercise Therapy; Gl | 1978 |
Drug control of gout and hyperuricaemia.
Topics: Allopurinol; Arthritis; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Naproxen; Phenylbut | 1978 |
Pharmacologic approach to the maintenance of urate homeostasis.
Topics: Allopurinol; Diuresis; Gout; Homeostasis; Humans; Kidney Tubules; Probenecid; Sulfinpyrazone; Uric A | 1975 |
Hyperuricemia and gout.
Topics: Acute Disease; Adult; Allopurinol; Anti-Inflammatory Agents; Arthritis; Arthrography; Calcinosis; Ch | 1986 |
[Gout: diagnosis and therapy].
Topics: Allopurinol; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Probenecid; Sulfinpyrazone | 1985 |
Arthritis & other rheumatic diseases. I. Introduction.
Topics: Adrenocorticotropic Hormone; Allopurinol; Analgesics; Arthritis, Juvenile; Arthritis, Rheumatoid; Co | 1971 |
Crystal deposition joint disease.
Topics: Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Colchicine; Crystallization; Diphosphates; Female; G | 1974 |
Milestones in the treatment of gout.
Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Kidney Calculi; Probenecid; Sulfinpyrazone; Uri | 1974 |
Principles of current management of primary gout.
Topics: Adult; Allopurinol; Diet Therapy; Female; Gout; Humans; Male; Middle Aged; Probenecid; Sulfinpyrazon | 1967 |
[Antarthritics. 41].
Topics: Acute Disease; Allopurinol; Antineoplastic Agents; Benzofurans; Colchicine; Female; Gout; Humans; Ph | 1969 |
[Drug therapy in gout].
Topics: Allopurinol; Chemical Phenomena; Chemistry; Colchicine; Gout; Humans; Phagocytosis; Probenecid; Puri | 1971 |
Treatment of gout.
Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Gout; Humans; Indomethacin; Phenylbutazone; Proben | 1971 |
[What is certain in gout therapy?].
Topics: Acute Disease; Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Hydrogen-Ion Concentration; K | 1971 |
Drug treatment of gout.
Topics: Acute Disease; Allopurinol; Arthritis; Colchicine; Gout; Humans; Orotic Acid; Probenecid; Structure- | 1971 |
Uricosuric drugs, with special reference to probenecid and sulfinpyrazone.
Topics: Gout; Humans; Male; Probenecid; Sulfinpyrazone; Uricosuric Agents | 1966 |
11 trials available for probenecid and Gout
| Article | Year |
|---|---|
Early urate-lowering therapy in gouty arthritis with acute flares: a double-blind placebo controlled clinical trial.
Topics: Arthritis, Gouty; Chronic Disease; Colchicine; Gout; Gout Suppressants; Humans; Probenecid; Symptom | 2023 |
Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout.
Topics: Allopurinol; Drug Interactions; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Male; Mi | 2011 |
Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients.
Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gou | 2007 |
Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol.
Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Admin | 2009 |
Effect of hypouricemic agents on serum carbohydrate-deficient transferrin in gouty patients.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Allopurinol; Benzbromarone; Chromatography, Ion Ex | 1994 |
Risks and benefits of drugs used in the management and prevention of gout.
Topics: Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Doubl | 1994 |
Ticrynafen and probenecid in hyperuricemic, hypertensive men.
Topics: Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Diuresis; Double-Blind Me | 1979 |
Treatment of gout and hyperuricaemia by benzbromarone, ethyl 2 (dibromo-3,5 hydroxy-4 benzoyl)-3 benzofuran.
Topics: Benzoates; Bromine; Clinical Trials as Topic; Creatinine; Gout; Humans; Hypoxanthines; Probenecid; P | 1974 |
Allopurinol in the treatment of gout.
Topics: Adult; Clinical Trials as Topic; Gout; Humans; Male; Middle Aged; Probenecid; Pyrimidines; Uricosuri | 1966 |
Comparison of allopurinol and probenecid.
Topics: Allopurinol; Clinical Trials as Topic; Colchicine; Enzyme Therapy; Follow-Up Studies; Gout; Humans; | 1966 |
Effect of drugs on urate binding to plasma proteins.
Topics: Adult; Allopurinol; Arthritis; Aspirin; Blood Proteins; Chromatography, DEAE-Cellulose; Colchicine; | 1969 |
222 other studies available for probenecid and Gout
| Article | Year |
|---|---|
Urate transport via human PAH transporter hOAT1 and its gene structure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Biological Transport; Blotting, Western; Car | 2003 |
Burden and management of gout in a multi-ethnic Asian cohort.
Topics: Adult; Aged; Allopurinol; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Dyslipidemias; Em | 2020 |
High-Protein Diet Induces Hyperuricemia in a New Animal Model for Studying Human Gout.
Topics: Allopurinol; Animal Structures; Animals; Chickens; Crystallization; Diet, High-Protein; Disease Mode | 2020 |
Trends in Utilization of Urate-Lowering Therapies Following the US Food and Drug Administration's Boxed Warning on Febuxostat.
Topics: Allopurinol; Cardiovascular Diseases; Cause of Death; Drug Labeling; Febuxostat; Gout; Gout Suppress | 2021 |
Effective uric acid reduction with probenecid and febuxostat in a patient with chronic kidney disease.
Topics: Adult; Chronic Disease; Drug Therapy, Combination; Febuxostat; Foot Deformities, Acquired; Gout; Gou | 2018 |
Treating Gout in Patients With Cardiovascular Disease: Mutual Benefit or Unintended Consequences?
Topics: Aged; Allopurinol; Cardiovascular Diseases; Gout; Humans; Probenecid; Risk Factors | 2018 |
Cardiovascular Risks of Probenecid Versus Allopurinol in Older Patients With Gout.
Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Cardiovascular Diseases; Cohort Studies; Female; | 2018 |
Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007-2016.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hy | 2019 |
Efficacy and tolerability of probenecid as urate-lowering therapy in gout; clinical experience in high-prevalence population.
Topics: Adult; Aged; Female; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Male; Middle Aged; | 2013 |
The real world of gout.
Topics: Female; Gout; Gout Suppressants; Humans; Male; Probenecid | 2013 |
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012.
Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidit | 2017 |
Achieving serum urate targets in gout: an audit in a gout-oriented rheumatology practice.
Topics: Aged; Allopurinol; Biomarkers; Drug Substitution; Febuxostat; Female; Gout; Gout Suppressants; Human | 2017 |
Opportunities for improving medication use and monitoring in gout.
Topics: Aged; Allopurinol; Biomarkers; Colchicine; Drug Administration Schedule; Drug Monitoring; Female; Go | 2009 |
Adherence with urate-lowering therapies for the treatment of gout.
Topics: Age Factors; Allopurinol; Female; Gout; Gout Suppressants; Humans; Male; Medication Adherence; Middl | 2009 |
Ultrasonography shows disappearance of monosodium urate crystal deposition on hyaline cartilage after sustained normouricemia is achieved.
Topics: Aged; Aged, 80 and over; Allopurinol; Cartilage, Articular; Colchicine; Crystallization; Female; Gou | 2010 |
On call. I've had gout for many years. I used to take Zyloprim without any problems, but I just had a severe allergic reaction, so my doctor switched me to Benemid. I'm doing okay, but the drug sometimes upsets my stomach. Do you have any suggestions?
Topics: Allopurinol; Drug Hypersensitivity; Gastritis; Gout; Gout Suppressants; Humans; Male; Middle Aged; P | 2010 |
Prevalence of contraindications and prescription of pharmacologic therapies for gout.
Topics: Aged; Aged, 80 and over; Allopurinol; Colchicine; Comorbidity; Contraindications; Diabetes Mellitus; | 2011 |
Catastrophic axial gout causing paraplegia in a patient with glycogen storage disease.
Topics: Adult; Catastrophic Illness; Drug Therapy, Combination; Febuxostat; Glycogen Storage Disease Type I; | 2011 |
How clinical and research failures lead to suboptimal prescribing: the example of chronic gout.
Topics: Allopurinol; Chronic Disease; Drug Discovery; Drug Utilization; Gout; Gout Suppressants; Guideline A | 2011 |
The pharmacokinetics of oxypurinol in people with gout.
Topics: Adult; Aged; Aged, 80 and over; Diuretics; Drug Interactions; Enzyme Inhibitors; Female; Gout; Gout | 2012 |
Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid.
Topics: Allopurinol; Chronic Disease; Contraindications; Febuxostat; Gout; Gout Suppressants; Humans; Male; | 2012 |
Adherence to uric acid treatment guidelines in a rheumatology clinic.
Topics: Aged; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Guideline Adherence; Humans; Male; M | 2012 |
Clinical and metabolic effects of benemid.
Topics: Gout; Probenecid | 1952 |
Diagnosis and treatment of gouty arthritis.
Topics: Arthritis; Arthritis, Gouty; Colchicine; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid; | 1953 |
Metabolism of uric acid and its relation to gout.
Topics: Gout; Humans; Probenecid; Uric Acid | 1954 |
[Probenecid and its use in therapy of gout].
Topics: Gout; Probenecid | 1953 |
[Therapy of chronic gout with benemid and cortisone].
Topics: Arthritis, Gouty; Chronic Disease; Cortisone; Gout; Probenecid | 1954 |
Studies on the effect of probenecid (benemid) in gout.
Topics: Gout; Probenecid | 1954 |
[Use of benemid in the treatment of gout].
Topics: Gout; Probenecid | 1954 |
[Probenecid in therapy of gout].
Topics: Gout; Probenecid | 1954 |
Sodium salicylate and probenecid in the treatment of chronic gout; assessment of their relative effects in lowering serum uric acid levels.
Topics: Arthritis, Gouty; Blood; Chronic Disease; Gout; Humans; Probenecid; Salicylates; Sodium Salicylate; | 1954 |
Further observation on the uricosuric effects of probenecid (benemid) in tophaceous gout.
Topics: Body Fluids; Gout; Humans; Probenecid; Uric Acid; Urine | 1954 |
Probenecid (benemid); its uses and side-effects in 2,502 patients.
Topics: Gout; Probenecid | 1955 |
Gout--now amenable to control.
Topics: Gout; Probenecid | 1955 |
[Clinical manifestations of uratic gout].
Topics: Gout; Probenecid | 1955 |
Reversal of renal insufficiency in gout; report of a case treated with probenecid (benemid).
Topics: Gout; Humans; Kidney Diseases; Probenecid; Renal Insufficiency | 1955 |
[Gout, joint diseases; trial therapy with benemid].
Topics: Gout; Joint Diseases; Probenecid | 1955 |
Effects of probenecid, cinchophen and colchicine on the plasma concentration and renal excretion of oxypurine in patients with gout.
Topics: Biochemical Phenomena; Colchicine; Gout; Humans; Probenecid; Purines; Quinolines; Renal Elimination | 1955 |
[Hyaluronidase and probenecid combination in the treatment of gout].
Topics: Gout; Humans; Hyaluronoglucosaminidase; Probenecid | 1956 |
Treatment of gout.
Topics: Analgesics; Antineoplastic Agents; Colchicine; Gout; Humans; Probenecid | 1956 |
Management of gout.
Topics: Diet; Disease Management; Gout; Humans; Probenecid; Salicylates | 1957 |
Management of gout.
Topics: Diet; Disease Management; Gout; Humans; Probenecid; Salicylates | 1957 |
Management of gout.
Topics: Diet; Disease Management; Gout; Humans; Probenecid; Salicylates | 1957 |
Management of gout.
Topics: Diet; Disease Management; Gout; Humans; Probenecid; Salicylates | 1957 |
[Clinical & metabolic effects of para (dipropylsulfamyl) benzoic acid in a case of severe gout].
Topics: Benzoic Acid; Female; Gout; Humans; Parity; Probenecid | 1957 |
[Gout and gouty arthritis].
Topics: Arthritis, Gouty; Gout; Humans; Phenylbutazone; Probenecid | 1957 |
Current therapeutics. CXX. Probenecid.
Topics: Gout; Probenecid | 1957 |
[Medical treatment of chronic gout].
Topics: Arthritis, Gouty; Chronic Disease; Gout; Probenecid; Sulfanilamide; Sulfanilamides; Sulfonamides | 1957 |
[Porbenecid treatment of uratic arthritis].
Topics: Arthritis; Gout; Humans; Probenecid | 1957 |
Gout and collagen disease.
Topics: Collagen Diseases; Gout; Humans; Prednisone; Probenecid | 1958 |
[Note on uraturia in gout patients during benemid therapy].
Topics: Body Fluids; Gout; Probenecid; Uric Acid | 1958 |
Selected aspects of acute and chronic gouty arthritis; an internist's interpretation of an orthopaedist's experiences with gout and gouty arthritis.
Topics: Arthritis, Gouty; Chronic Disease; Colchicine; Gout; Humans; Orthopedics; Probenecid | 1958 |
Probenecid (benemid) in the treatment of gout and gouty arthritis.
Topics: Arthritis, Gouty; Gout; Humans; Minnesota; Probenecid | 1959 |
Gout: six-year follow-up on probenecid (benemid) therapy.
Topics: Follow-Up Studies; Gout; Probenecid | 1959 |
Nephrotic syndrome caused by probenecid.
Topics: Gout; Humans; Nephrotic Syndrome; Probenecid | 1961 |
Available uricosuric agents.
Topics: Gout; Humans; Probenecid; Uricosuric Agents; Zoxazolamine | 1960 |
Long-term (six to seven years) therapy of gout.
Topics: Gout; Humans; Probenecid | 1960 |
[On probenecid treatment of chronic gout. Report of a severe complication of treatment].
Topics: Arthritis, Gouty; Chronic Disease; Gout; Humans; Probenecid; Uremia | 1962 |
Long term uricosuric therapy in gout.
Topics: Gout; Phenylbutazone; Probenecid; Salicylates; Uric Acid; Zoxazolamine | 1962 |
[Gout].
Topics: Gout; Probenecid; Pyrazoles; Quinolines; Zoxazolamine | 1962 |
[Clinical aspects of gout, based on personal observation of 40 cases].
Topics: Gout; Phenylbutazone; Prednisolone; Probenecid; Pyrazoles; Salicylates; Zoxazolamine | 1962 |
The search for uricosuric agents suited to the management of tophaceous gout.
Topics: Disease Management; Gout; Humans; Probenecid; Uricosuric Agents | 1963 |
Gout.
Topics: Adrenocorticotropic Hormone; Colchicine; Gout; Hydrocortisone; Phenylbutazone; Probenecid; Pyrazoles | 1962 |
[Uricosuria therapy of chronic gout].
Topics: Arthritis; Chronic Disease; Gout; Humans; Probenecid; Uric Acid; Urologic Diseases | 1963 |
[The use of uricosuric agents].
Topics: Gout; Humans; Probenecid; Uric Acid; Uricosuric Agents | 1963 |
[The treatment of gout by probenecid (A study based on 156 cases, 68 of which were treated from 1 to 9 years)].
Topics: Gout; Humans; Probenecid | 1963 |
[Uricosuric medication. Value of the products of the aminochlorobenzoxazole series].
Topics: Colchicine; Gout; Probenecid; Zoxazolamine | 1962 |
Uricosuric treatment in angina pectoris.
Topics: Angina Pectoris; Colchicine; Gout; Humans; Probenecid | 1963 |
URICOSURIC AGENTS AND PHENOLSULFONPHTHALEIN EXCRETION.
Topics: Gout; Humans; Kidney Function Tests; Phenolphthaleins; Phenolsulfonphthalein; Probenecid; Uricosuric | 1963 |
INFLAMMATORY POLYARTHRITIC DISEASE. IV. GOUT.
Topics: Arthritis; Aspirin; Chlorothiazide; Colchicine; Gout; Hydrochlorothiazide; Mecamylamine; Pempidine; | 1963 |
[URICO-ELIMINATOR TREATMENT OF CHRONIC GOUT].
Topics: Arthritis, Gouty; Gout; Phenylbutazone; Probenecid; Pyrazoles; Salicylates; Uricosuric Agents; Zoxaz | 1963 |
[ASSESSMENT OF 172 CASES OF CHRONIC GOUT TREATED BY PROBENECID FOR 10 YEARS].
Topics: Acute Kidney Injury; Arthritis, Gouty; Gout; Humans; Kidney Calculi; Probenecid; Renal Insufficiency | 1963 |
GOUT AND SALT-WASTING RENAL DISEASE DURING PREGNANCY; DIAGNOSIS, MANAGEMENT, AND FOLLOW-UP.
Topics: Blood Chemical Analysis; Colchicine; Diet Therapy; Diet, Sodium-Restricted; Female; Follow-Up Studie | 1963 |
COEXISTENT SARCOIDOSIS, ERYTHEMA NODOSUM, AND GOUT.
Topics: Cortisone; Deoxyribonuclease I; Erythema Nodosum; Gout; Humans; Isoniazid; Pathology; Prednisone; Pr | 1963 |
TREATMENT OF THE PATIENT WITH GOUT.
Topics: Chlorthalidone; Colchicine; Diagnosis; Gout; Humans; Oxyphenbutazone; Phenylbutazone; Probenecid; Py | 1963 |
GOUT. A FIVE-YEAR REVIEW.
Topics: Adrenocorticotropic Hormone; Arthritis; Aspirin; Codeine; Colchicine; Diagnosis, Differential; Diet; | 1963 |
[A CASE OF ATYPICAL GOUT].
Topics: Adrenocorticotropic Hormone; Colchicine; Gout; Humans; Phenylbutazone; Probenecid | 1963 |
MEDICAL GRAND ROUNDS FROM THE UNIVERSITY OF ALABAMA MEDICAL CENTER.
Topics: Arthritis; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Teaching Rounds; Uric Acid | 1964 |
ASSOCIATION OF HYPERURICAEMIA AND GOUT WITH HYPERPARATHYROIDISM.
Topics: Adenoma; Blood Chemical Analysis; Diagnosis; Gout; Humans; Hyperparathyroidism; Hyperuricemia; Nephr | 1964 |
DRUGS FOR GOUT.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Diuretics; Gout; Griseofulvin; Hum | 1964 |
[THE TREATMENT OF CHRONIC INFLAMMATORY RHEUMATISM IN ADULTS].
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis; Arthritis, Rheumatoid; Aspirin; Colchicine; Colla | 1964 |
THE MODERN MANAGEMENT OF GOUT.
Topics: Adrenocorticotropic Hormone; Blood; Body Fluids; Colchicine; Diet; Diet Therapy; Disease Management; | 1964 |
ATYPICAL GOUT.
Topics: Arthritis; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Geriatrics; Gout; Humans; Ost | 1964 |
EXHIBIT ON GOUT.
Topics: Colchicine; Exhibitions as Topic; Gout; Humans; Metabolism; Probenecid; Purines; Sulfinpyrazone; Uri | 1964 |
THE TREATMENT OF GOUT.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Diet; Diet Therapy; Dr | 1964 |
GOUT.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Colchicine; Diagnosis, Differential; Diet; Diet | 1964 |
EFFECT OF SULFINPYRAZONE ON SERUM URIC ACID IN GOUT. A LONG-TERM STUDY.
Topics: Adolescent; Aging; Blood; Drug Therapy; Geriatrics; Gout; Longitudinal Studies; Metabolism; Phenylbu | 1964 |
4-HYDROXYPYRAZOLO (3,4-D) PYRIMIDINE (HPP) IN THE TREATMENT OF GOUT: PRELIMINARY OBSERVATIONS.
Topics: Blood; Colchicine; Diet; Diet Therapy; Drug Therapy; Enzyme Inhibitors; Geriatrics; Gout; Humans; Pr | 1964 |
THE PROGRESSIVE NATURE OF GOUT WITH INADEQUATE THERAPY.
Topics: Diagnosis; Drug Therapy; Gout; Humans; Pathology; Probenecid; Radiography; Sulfinpyrazone | 1965 |
PROBENECID (BENEMID) INTOXICATION WITH STATUS EPILEPTICUS.
Topics: Coma; Drug Therapy; Epilepsy; Gout; Phenobarbital; Phenytoin; Poisoning; Probenecid; Status Epilepti | 1965 |
THE RENAL EXCRETION OF OXYPURINES.
Topics: Enzyme Inhibitors; Fluids and Secretions; Gout; Hypoxanthines; Kidney; Pharmacology; Physiology; Pro | 1965 |
[GOUT, DIAGNOSIS AND TREATMENT].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Diagnosis; Drug Therapy; Gout; Hum | 1965 |
URATE DIURETIC THERAPY IN CHRONIC GOUT; A COMPARATIVE STUDY OF PROBENECID AND SULFINPYRAZONE.
Topics: Arthritis, Gouty; Biomedical Research; Blood; Diuretics; Drug Therapy; Gout; Humans; Kidney Calculi; | 1965 |
ACUTE ANAPHYLACTOID REACTION TO PROBENECID.
Topics: Anaphylaxis; Colchicine; Diagnosis, Differential; Drug Therapy; Gout; Myocardial Infarction; Probene | 1965 |
GOUT IN THE ELDERLY. MODERN MANAGEMENT IN HISTORICAL PERSPECTIVE.
Topics: Aged; Colchicine; Diagnosis; Diet; Diet Therapy; Drug Therapy; Geriatrics; Gout; History; Humans; Ph | 1965 |
[SEVERE GOUT IN A YOUNG MAN. TREATMENT WITH BENEMID AND INDOMETHACIN].
Topics: Gout; Humans; Indoles; Indomethacin; Male; Probenecid; Uricosuric Agents | 1965 |
Inhibition of the uricosuric action of benemid by salicylate.
Topics: Body Fluids; Gout; Probenecid; Salicylates; Uric Acid; Urine | 1955 |
[Treatment of gout with benemid].
Topics: Gout; Probenecid | 1955 |
[Influence of Benemid and colchicine on nitrogen metabolism in gout].
Topics: Colchicine; Gout; Leadership; Nitrogen; Probenecid | 1962 |
Uricosuric effects of probenecid and zoxazolamine in gout. A comparative study.
Topics: Gout; Probenecid; Zoxazolamine | 1961 |
The effect of benemid (P-[DI-N-propylsulfamyl]-benzoic acid) on uric acid metabolism in one normal and one gouty subject.
Topics: Benzoic Acid; Gout; Humans; Probenecid; Uric Acid | 1951 |
Benemid (p-di-n-propylsulfamyl)-benzoic acid) as uricosuric agent in chronic gouty arthritis.
Topics: Arthritis, Gouty; Benzoic Acid; Body Fluids; Chronic Disease; Gout; Probenecid; Uric Acid; Uricosuri | 1951 |
The clinical and metabolic effects of benemid in patients with gout.
Topics: Body Fluids; Gout; Probenecid; Uric Acid | 1951 |
Effect of benemid in gouty arthritis.
Topics: Aged; Arthritis, Gouty; Gout; Humans; Probenecid | 1951 |
Mobilization of gouty tophi by protracted use of uricosuric agents.
Topics: Dental Care; Gout; Humans; Physical Therapy Modalities; Probenecid; Sulfonamides; Uricosuric Agents | 1951 |
Clinical and metabolic effects of benemid in gout.
Topics: Gout; Probenecid | 1951 |
Therapeutic value of probenecid (benemid) in gout.
Topics: Gout; Probenecid | 1952 |
Effect of benemid (p-[di-n-propylsulfamyl]-benzoic acid) on urate clearance and other discrete renal functions in gouty subjects.
Topics: Benzoic Acid; Gout; Humans; Kinetics; Probenecid; Uric Acid | 1952 |
Febuxostat--treatment for hyperuricemia and gout?
Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thiazoles; Uric | 2005 |
Probenecid-induced membranous nephropathy.
Topics: Aged; Edema; Glomerulonephritis, Membranous; Gout; Humans; Male; Probenecid; Proteinuria; Uricosuric | 2007 |
Uric acid lowering therapy: prescribing patterns in a large cohort of older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Black or | 2008 |
Gout: joint pain and more.
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Gout; Gout Suppressa | 2007 |
Effect of food, fast and alcohol on serum uric acid and acute attacks of gout.
Topics: Adult; Aged; Butyrates; Dietary Proteins; Ethanol; Fasting; Female; Gout; Humans; Ketones; Lactates; | 1967 |
Studies of uric acid metabolism in glycogen storage disease associated with gouty arthritis.
Topics: Adolescent; Allopurinol; Body Height; Body Weight; Carbon Isotopes; Enzyme Therapy; Glucosephosphate | 1967 |
[Effect of benziodarone on the renal excretion of uric acid].
Topics: Gout; Humans; Probenecid; Pyrazinamide; Uricosuric Agents | 1967 |
[Study of 100 gout patients treated with benzodiarone].
Topics: Diuretics; Gout; Humans; Probenecid; Uricosuric Agents | 1967 |
Therapy of gout.
Topics: Allopurinol; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Sulfinpyrazone | 1967 |
Management of gout and hyperuricemia.
Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Gout; Humans; Indomethacin; Kidney; Patient Educa | 1984 |
Crystal-induced arthritis.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Arthritis; Calcium Pyrophosphate; Crystalli | 1982 |
Renal handling of uric acid in gout by means of the pyrazinamide and probenecid tests.
Topics: Adult; Gout; Humans; Kidney; Kidney Tubules; Probenecid; Pyrazinamide; Reference Values; Uric Acid | 1984 |
Calciuric effect of probenecid in gouty patients.
Topics: Adult; Aged; Calcium; Creatinine; Gout; Humans; Male; Middle Aged; Probenecid; Uric Acid | 1983 |
Co-existent tophaceous gout and systemic lupus erythematosus.
Topics: Adult; Allopurinol; Gout; Humans; Lupus Erythematosus, Systemic; Male; Probenecid | 1982 |
[Effect of long-term base therapy on the clinical picture of gout].
Topics: Adult; Allopurinol; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Gout; Human | 1981 |
Treatment of gout.
Topics: Gout; Humans; Probenecid; Uric Acid; Uricosuric Agents | 1981 |
Practical therapeutics treatment of gout.
Topics: Colchicine; Female; Gout; Humans; Indomethacin; Male; Phenylbutazone; Probenecid; Sulfinpyrazone | 1981 |
Diagnostic and therapeutic aids in gout and hyperuricemia.
Topics: Acute Disease; Allopurinol; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Gout; Humans | 1981 |
Effects of exercise performance on drugs used in musculoskeletal disorders.
Topics: Allopurinol; Analgesics; Anti-Inflammatory Agents; Bone Diseases; Colchicine; Gout; Humans; Muscle R | 1981 |
[Changes in indications for drugs].
Topics: Amantadine; Clofibrate; Colchicine; Drug Therapy; Female; Gout; Humans; Levamisole; Metronidazole; M | 1980 |
Renal handling of urate in a patient with familial juvenile gouty nephropathy.
Topics: Adolescent; Benzbromarone; Female; Genes, Dominant; Gout; Gout Suppressants; Humans; Kidney; Kidney | 1996 |
Gout due to xanthine derivatives.
Topics: Allopurinol; Aminophylline; Asthma; Benzbromarone; Bronchodilator Agents; Drug Therapy, Combination; | 1997 |
Apoptosis of tubular epithelial cells in familial juvenile gouty nephropathy.
Topics: Adult; Apoptosis; Benzbromarone; Biopsy; Biotin; Deoxyuracil Nucleotides; DNA Fragmentation; Family | 1998 |
Restoration of the uricosuric effect of probenecid after triglycylvasopressine administration in a gouty patient.
Topics: Absorption; Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Benzbromarone; Fludrocortisone; Go | 1998 |
[Gout: physiopathology, diagnosis, course, treatment].
Topics: Adult; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Diagnosis, Differential; Female; Gout; Go | 1998 |
[Hyperuricemia and gout--treatment].
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug | 2002 |
Physiological characteristics of various experimental models for the study of disorders in purine metabolism.
Topics: Acidosis; Alkalosis; Allopurinol; Animals; Cholesterol; Disease Models, Animal; Diuresis; Fructose; | 1977 |
[The gouty kidney: physiopathology, clinical aspects and therapy].
Topics: Benzofurans; Gout; Humans; Kidney Diseases; Probenecid | 1977 |
[Physiopathological bases for a rational therapy of gout].
Topics: Allopurinol; Benzofurans; Gout; Humans; Life Style; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric | 1978 |
Management of gout.
Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Female; Gout; Humans; Indomethacin; Patient Educat | 1979 |
Mechanism and treatment of hypertriglyceridaemia in gout.
Topics: Alcohol Drinking; Allopurinol; Cholesterol; Gout; Humans; Hyperlipidemias; Male; Middle Aged; Obesit | 1979 |
Gout.
Topics: Colchicine; Cortisone; Gout; Humans; Male; Probenecid; Sulfinpyrazone | 1979 |
The management of gout.
Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Male; Oxyphenbutazone; Phenylbutazone; Probenec | 1979 |
Treating gout: successful methods of prevention and control.
Topics: Acute Disease; Allopurinol; Colchicine; Gout; Humans; Probenecid | 1978 |
[Various aspects of nephropathy in gout].
Topics: Adult; Age Factors; Aged; Amyloidosis; Glomerular Filtration Rate; Gout; Humans; Hypertension, Renal | 1978 |
Management of gout.
Topics: Allopurinol; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Sulfinpyrazone | 1979 |
[Outline of gout therapy and selection of uric acid controlling agents].
Topics: Allopurinol; Gout; Humans; Probenecid | 1977 |
[Drug therapy in uratic arthritis. II. Prevention of new attacks].
Topics: Allopurinol; Gout; Humans; Probenecid; Sulfinpyrazone | 1977 |
[Comparison of effects of various therapeutic methods of the urinary system in patients with gout. Observations on 195 patients with gout].
Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Male; Middle Aged; Probenecid; Uric Acid; Urinary Tr | 1977 |
[Quantitative treatment for the gout based on the multivariant analysis--the theory for decision of hypouricemic agent by discriminant function (author's transl)].
Topics: Adult; Aged; Allopurinol; Analysis of Variance; Drug Evaluation; Gout; Humans; Middle Aged; Models, | 1977 |
The influence of allopurinol and size of dose on the metabolism of phenylbutazone in patients with gout.
Topics: Adult; Allopurinol; Dose-Response Relationship, Drug; Drug Interactions; Female; Gout; Half-Life; Hu | 1977 |
Drugs for gout.
Topics: Allopurinol; Colchicine; Gout; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Probenecid; Su | 1976 |
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; | 1976 |
Current therapy of gout and hyperuricemia.
Topics: Allopurinol; Colchicine; Drug Interactions; Gout; Humans; Indomethacin; Phenylbutazone; Probenecid; | 1976 |
Gouty arthritis in the black race.
Topics: Adult; Aged; Anemia, Sickle Cell; Arthritis; Benzothiadiazines; Black People; Colchicine; Diuretics; | 1975 |
Decreasing prevalence of tophaceous gout.
Topics: Colchicine; Gout; Humans; Minnesota; Probenecid; Retrospective Studies; Sulfinpyrazone | 1975 |
Gout: diagnosis and management.
Topics: Allopurinol; Anti-Inflammatory Agents; Gout; Humans; Probenecid; Uric Acid | 1975 |
[Effect of different therapeutic methods on the development of arthropathy in patients with gout. Observation of 155 cases].
Topics: Adult; Aged; Allopurinol; Colchicine; Gout; Humans; Joint Diseases; Middle Aged; Probenecid | 1975 |
[Recent advances in the treatment of gout - current concept of the treatment and its theoretical background].
Topics: Allopurinol; Gout; Humans; Probenecid | 1975 |
Unavailability of probenecid in Australia.
Topics: Australia; Drug Industry; Gout; Humans; New Zealand; Probenecid | 1992 |
The misdiagnosis of gout and hyperuricemia.
Topics: Adult; Aged; Allopurinol; Analysis of Variance; Arthritis, Psoriatic; Chondrocalcinosis; Colchicine; | 1991 |
Evaluation of allopurinol use in patients with gout.
Topics: Allopurinol; Costs and Cost Analysis; Gout; Humans; Hypertension; Probenecid; Radiography; Risk Fact | 1989 |
Possible cardioprotective effects of allopurinol.
Topics: Acute Disease; Aged; Allopurinol; Cohort Studies; Colchicine; Drug Combinations; Female; Gout; Healt | 1988 |
Polyarticular gout induced by probenecid therapy.
Topics: Aged; Arthritis; Gout; Humans; Male; Probenecid | 1986 |
[Effect of decrease in hyperuricemia levels on joint, kidney and other symptoms in patients with gout].
Topics: Adult; Aged; Allopurinol; Arthritis; Colchicine; Coronary Disease; Gout; Humans; Hypertension; Middl | 1987 |
Evaluation of the renal mechanisms for urate homeostasis in uremic patients by probenecid and pyrazinamide test.
Topics: Absorption; Creatinine; Female; Glomerular Filtration Rate; Gout; Homeostasis; Humans; Kidney Failur | 1987 |
Probenecid induced immune hemolytic anemia.
Topics: Anemia, Hemolytic, Autoimmune; Arthritis; Colchicine; Coombs Test; Drug Therapy, Combination; Gout; | 1986 |
Diminished tubular secretion of urate in gout not dependent on serum urate levels.
Topics: Adult; Aged; Gout; Humans; Kidney Tubules; Kinetics; Male; Middle Aged; Nephrons; Probenecid; Refere | 1986 |
Study of the effect of hypouricaemic therapy on serum lipid levels in gout patients.
Topics: Allopurinol; Cholesterol; Cholesterol, HDL; Gout; Humans; Lipids; Probenecid; Triglycerides; Uric Ac | 1986 |
Renal handling of uric acid in gout: impaired tubular transport of urate not dependent on serum urate levels.
Topics: Adult; Aged; Biological Transport, Active; Gout; Humans; Kidney Tubules; Kinetics; Male; Middle Aged | 1986 |
Hyperuricemia and gout.
Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Colchicine; Female; Gout; Humans; Indomethacin; Ki | 1985 |
Personal history of Paget's disease. Osteitis deformans with several unusual features and their control.
Topics: Aged; Blood Volume; Gout; Humans; Male; Osteitis Deformans; Probenecid | 1974 |
Drugs in the treatment of hyperuricemia.
Topics: Allopurinol; Gout; Humans; Oxypurinol; Probenecid; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 1974 |
Zyloprim and other drugs in the management of gout.
Topics: Adrenocorticotropic Hormone; Colchicine; Enzyme Therapy; Enzymes; Gout; Humans; Indomethacin; Proben | 1966 |
[The treatment of gout and the internal medical treatment of uric acid nephrolithiasis].
Topics: Adrenocorticotropic Hormone; Allopurinol; Colchicine; Gout; Humans; Indomethacin; Kidney Calculi; Pr | 1968 |
Recent developments in the therapy of gout.
Topics: Acute Disease; Adrenocorticotropic Hormone; Allopurinol; Analgesics; Colchicine; Gout; Humans; Oxyph | 1968 |
[How to treat gout].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticoagulants; Benzofurans; Colchicine; Gout; | 1966 |
Management of chronic and recurrent gout.
Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy; | 1971 |
Gout and hyperlipidaemia.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Aspartate Aminotransferases; Body Height; Body Weight; C | 1974 |
Letter: Drug therapy of cerebral palsy.
Topics: Anxiety; Cerebral Palsy; Diazepam; Drug Therapy, Combination; Gout; Humans; Male; Probenecid | 1974 |
[Modern therapy of gout].
Topics: Acute Disease; Chronic Disease; Colchicine; Diet, Reducing; Female; Gout; Humans; Indomethacin; Kidn | 1972 |
Effect of balneotherapy in Ciechocinek Spa on the occurrence of gouty attacks and the symptoms of chronic gouty arthropathy (observations of 112 cures).
Topics: Adult; Aged; Allopurinol; Balneology; Blood Sedimentation; Colchicine; Female; Gout; Humans; Male; M | 1972 |
Gout.
Topics: Allopurinol; Blood Cell Count; Cell Movement; Colchicine; Diet; Drug Synergism; Gastrointestinal Dis | 1974 |
The binding of urate to plasma proteins.
Topics: Allopurinol; Aspirin; Binding Sites; Blood Proteins; Colchicine; Dialysis; Evaluation Studies as Top | 1974 |
Medical management of gout.
Topics: Adult; Allopurinol; Colchicine; Diet Therapy; Female; Gout; Humans; Kidney Diseases; Male; Middle Ag | 1972 |
Probenecid-induced nephrotic syndrome.
Topics: Antigen-Antibody Reactions; Basement Membrane; Biopsy; Epithelial Cells; Gout; Humans; Kidney; Kidne | 1972 |
Azoospermia caused by colchicine--a case report.
Topics: Adult; Cell Count; Colchicine; Gout; Humans; Iatrogenic Disease; Infertility, Male; Male; Probenecid | 1972 |
[Podagric arthropathy].
Topics: Adolescent; Adult; Albuminuria; Algeria; Cardiovascular Diseases; Child; Child, Preschool; Cholester | 1971 |
[A case report of von Gierke's disease with tophaceous gout].
Topics: Adult; Allopurinol; Glycogen Storage Disease Type I; Gout; Humans; Male; Pedigree; Probenecid | 1968 |
Gout of the temporomandibular joint. Report of three cases.
Topics: Colchicine; Diagnosis, Differential; Gout; Humans; Male; Middle Aged; Probenecid; Temporomandibular | 1969 |
Drug-induced hyperuricemia prevented by probenecid.
Topics: Adult; Aged; Female; Gout; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Probenecid; | 1971 |
[Gout from the view of a special hospital for rheumatic patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Austria; Child; Cholesterol; Colchicine; Colic; Diabetes Com | 1971 |
[Uric arthritis of the hip joint. Differential diagnosis of the idiopathic femur head necrosis].
Topics: Adult; Diagnosis, Differential; Femur Head; Gout; Hip Joint; Humans; Male; Necrosis; Phenylbutazone; | 1969 |
[Gout in dermatology].
Topics: Adolescent; Aged; Colchicine; Diagnosis, Differential; Gout; Humans; Indomethacin; Joint Diseases; M | 1969 |
Pathogenesis and medical management of chronic gouty arthritis.
Topics: Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Joints; Kidney; Probenecid; Sulfinpyrazone; | 1970 |
Effect of glycine loading on plasma and urinary uric acid and amino acids in normal and gouty subjects.
Topics: Adult; Aged; Amino Acids; Glycine; Gout; Humans; Hydrogen-Ion Concentration; Kidney; Male; Middle Ag | 1970 |
[Association of a uricosuric and a uric acid inhibitor in the prophylaxis and treatment of the basis of gout].
Topics: Female; Gout; Humans; Male; Orotic Acid; Probenecid | 1970 |
The influence of allopurinol on the course of gout. A study of 28 cases.
Topics: Age Factors; Allopurinol; Colchicine; Drug Synergism; Gout; Humans; Probenecid; Uric Acid | 1970 |
[Clinical aspects of gout].
Topics: Allopurinol; Cerebrovascular Disorders; Colchicine; Diagnosis, Differential; Diet Therapy; Female; G | 1970 |
[Basic principles and accomplishments of the current gout therapy].
Topics: Adult; Aged; Allopurinol; Colchicine; Diagnosis, Differential; Gout; Humans; Middle Aged; Phenylbuta | 1970 |
[Allopurinol in the treatment of gout].
Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Male; Middle Aged; Probenecid; Uric Acid | 1970 |
Hyperlipoproteinaemia in gout.
Topics: Adult; Aged; Allopurinol; Blood Protein Disorders; Blood Protein Electrophoresis; Cholesterol; Gout; | 1971 |
[Ethamide--a drug for the therapy of gout and other conditions associated with accumulation of uric acid in the body].
Topics: Adult; Aged; Female; Gout; Humans; Male; Probenecid; Toe Joint; Uric Acid | 1967 |
Problems and progress in geriatrics.
Topics: Acute Disease; Aged; Aging; Calcitonin; Cardiovascular Diseases; Chronic Disease; Diabetic Coma; Dia | 1968 |
Probenecid, nephrotic syndrome, and renal failure.
Topics: Acute Kidney Injury; Aged; Edema; Gout; Humans; Male; Middle Aged; Nephrotic Syndrome; Probenecid; P | 1968 |
Renal clearance of oxipurinol, the chief metabolite of allopurinol.
Topics: Allopurinol; Animals; Dogs; Gout; Humans; Kidney; Kidney Function Tests; Probenecid; Spectrophotomet | 1968 |
[Therapy of arthritis urica].
Topics: Analgesics; Diet Therapy; Gout; Humans; Probenecid; Sulfinpyrazone | 1968 |
Etiology and treatment of gout--modern concepts.
Topics: Allopurinol; Colchicine; Crystallization; Diagnosis, Differential; Diet Therapy; Gout; Humans; Indom | 1968 |
A short trial assessment of uricosuric therapy in gout.
Topics: Adult; Aged; Allopurinol; Female; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Probe | 1968 |
[Allopurinol in the treatment of gout].
Topics: Adult; Allopurinol; Gout; Humans; Indomethacin; Male; Middle Aged; Probenecid; Uric Acid | 1968 |
[Therapy of gout in surgical patients].
Topics: Achilles Tendon; Allopurinol; Cortisone; Diagnosis, Differential; Gout; Humans; Joint Diseases; Male | 1968 |
Gout and uveitis. Report of a case.
Topics: Adult; Colchicine; Gout; Humans; Male; Probenecid; Steroids; Uric Acid; Uveitis | 1968 |
Ethebenecid (Urelim).
Topics: Benzoates; Gout; Humans; Probenecid; Sulfonamides; Uricosuric Agents | 1968 |
[Gout in advanced age].
Topics: Age Factors; Aged; Allopurinol; Bone and Bones; Cardiovascular Diseases; Colchicine; Female; Gout; H | 1968 |
Goals in gout.
Topics: Allopurinol; Colchicine; Gout; Humans; Probenecid; Sulfinpyrazone | 1969 |
Difficult case of gout.
Topics: Fingers; Gout; Humans; Male; Middle Aged; Probenecid; Radiography; Salicylates | 1969 |
Gouty arthritis as a complication of acetazolamide (Diamox) therapy for glaucoma.
Topics: Acetazolamide; Colchicine; Glaucoma; Gout; Humans; Male; Middle Aged; Probenecid | 1969 |
Treatment of primary gout: the present status.
Topics: Colchicine; Enzyme Therapy; Gout; Humans; Kidney Calculi; Oxyphenbutazone; Phenylbutazone; Probeneci | 1965 |
[Benemid in the treatment of primary and secondary gout].
Topics: Gout; Humans; Probenecid | 1965 |
Gout in orthopaedic practice: review of 232 cases.
Topics: Acute Disease; Adolescent; Aged; Bone Diseases; Chlorothiazide; Colchicine; Diagnosis, Differential; | 1963 |
[Surgical treatment of hands severely deformed by gout].
Topics: Aged; Blood Vessels; Colchicine; Gout; Hand; Hand Deformities, Acquired; Humans; Male; Preoperative | 1965 |
[Disappearance of gouty geodes in the bones of the hand].
Topics: Gout; Hand; Humans; Male; Middle Aged; Probenecid | 1966 |
The effects of allopurinol on serum and urinary uric acid.
Topics: Adult; Aged; Blood; Enzymes; Female; Gout; Humans; Male; Probenecid; Uric Acid; Urinary Calculi; Uri | 1966 |
An extended study of indomethacin. II. Clinical therapy.
Topics: Adolescent; Adult; Arthritis; Arthritis, Rheumatoid; Aspirin; Child; Female; Gout; Humans; Indometha | 1966 |
Allopurinol (xanthine oxidase inhibitor) in the treatment of resistant gout.
Topics: Adult; Aged; Colchicine; Enzyme Therapy; Enzymes; Female; Gout; Humans; Male; Middle Aged; Probeneci | 1966 |
Allopurinol therapy of gout with renal complications.
Topics: Adult; Allopurinol; Calcium; Creatine; Enzyme Therapy; Gout; Humans; Kidney Failure, Chronic; Male; | 1966 |
[Clinical aspects of chronic gout].
Topics: Adult; Aged; Allopurinol; Anemia; Arthritis; Bicarbonates; Blood Sedimentation; Chronic Disease; Fem | 1966 |