probenecid has been researched along with Gastroesophageal Reflux in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder." | 1.62 | Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis. ( Kato, S; Matsui, K; Matsumoto, K; Mizutani, Y; Nakamoto, T; Suenaga, M; Yoshida, A, 2021) |
| "Patients with gout have comorbidities, but the impact of these comorbidities on treatment has not been studied." | 1.37 | Prevalence of contraindications and prescription of pharmacologic therapies for gout. ( Crittenden, DB; Fisher, MC; Goldfarb, DS; Keenan, RT; Krasnokutsky, S; Lee, KH; O'Brien, WR; Oh, C; Pillinger, MH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, K | 1 |
| Suenaga, M | 1 |
| Mizutani, Y | 1 |
| Matsui, K | 1 |
| Yoshida, A | 1 |
| Nakamoto, T | 1 |
| Kato, S | 1 |
| Keenan, RT | 1 |
| O'Brien, WR | 1 |
| Lee, KH | 1 |
| Crittenden, DB | 1 |
| Fisher, MC | 1 |
| Goldfarb, DS | 1 |
| Krasnokutsky, S | 1 |
| Oh, C | 1 |
| Pillinger, MH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ACTH vs Betamethasone for the Treatment of Acute Gout in Hospitalized Patients: A Randomized, Open Label, Comparative Study[NCT04306653] | 60 participants (Anticipated) | Interventional | 2018-01-05 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for probenecid and Gastroesophageal Reflux
| Article | Year |
|---|---|
Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis.
Topics: Animals; Disease Models, Animal; Esophageal Sphincter, Lower; Gastroesophageal Reflux; Gene Expressi | 2021 |
Prevalence of contraindications and prescription of pharmacologic therapies for gout.
Topics: Aged; Aged, 80 and over; Allopurinol; Colchicine; Comorbidity; Contraindications; Diabetes Mellitus; | 2011 |