probenecid has been researched along with Erythema Chronicum Migrans in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Erythema Chronicum Migrans: A deep type of gyrate erythema that follows a bite by an ixodid tick; it is a stage-1 manifestation of LYME DISEASE. The site of the bite is characterized by a red papule that expands peripherally as a nonscaling, palpable band that clears centrally. This condition is often associated with systemic symptoms such as chills, fever, headache, malaise, nausea, vomiting, fatigue, backache, and stiff neck.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the safety and efficacy of azithromycin, amoxicillin/probenecid, and doxycycline for the treatment of early Lyme disease, to identify risk factors for treatment failure, and to describe the serologic response in treated patients." | 5.07 | Treatment of early Lyme disease. ( Johnson, RC; Luger, SW; Massarotti, EM; Messner, RP; Rahn, DW; Steere, AC; Wong, JB, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massarotti, EM | 1 |
| Luger, SW | 1 |
| Rahn, DW | 1 |
| Messner, RP | 1 |
| Wong, JB | 1 |
| Johnson, RC | 2 |
| Steere, AC | 1 |
| Berger, BW | 1 |
1 trial available for probenecid and Erythema Chronicum Migrans
| Article | Year |
|---|---|
Treatment of early Lyme disease.
Topics: Adult; Amoxicillin; Antibodies, Bacterial; Azithromycin; Borrelia burgdorferi Group; Doxycycline; Er | 1992 |
1 other study available for probenecid and Erythema Chronicum Migrans
| Article | Year |
|---|---|
Clinical and microbiologic findings in six patients with erythema migrans of Lyme disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Borrelia burgdorferi Group; Drug Resistance, Microbial; Erythema | 1989 |