Compounds > probenecid
Page last updated: 2024-11-03

probenecid and Endocarditis

probenecid has been researched along with Endocarditis in 12 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.

Research Excerpts

ExcerptRelevanceReference
"Hematuria and eosinophilia developed in two patients being treated for bacterial endocarditis with 20 or 24 gm/day of cephalexin given orally together with probenecid (Benemid)."3.65Cephalexin-related nephropathy. ( Kieff, E; Verma, S, 1975)
"Extraneous infective endocarditis is most often caused by staphylococci, with Gram-negative bacilli and fungi also quite frequent infecting agents."1.25The choice of antibiotic for treating infective endocarditis. ( Gray, IR, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TURK, DC1
WILSON, CT1
NICHOLS, RL2
RICHARDS, WA2
FINLAND, M2
WOLNISTY, C1
FRIEDMAN, SL1
ROBINSON, OP1
SILBERSTEIN, EB1
BROUGHTON, CR1
BAKER, GP1
PILKINGTON, T1
Gray, IR2
Verma, S1
Kieff, E1
Knudsen, ET1

Other Studies

12 other studies available for probenecid and Endocarditis

ArticleYear
A case of enterococcal endocarditis.
    Guy's Hospital reports, 1954, Volume: 103, Issue:3

    Topics: Bacterial Infections; Bacteriology; Endocarditis; Endocarditis, Subacute Bacterial; Humans; Penicill

1954
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
    The American journal of the medical sciences, 1957, Volume: 233, Issue:3

    Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design

1957
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
    The American journal of the medical sciences, 1957, Volume: 233, Issue:3

    Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design

1957
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
    The American journal of the medical sciences, 1957, Volume: 233, Issue:3

    Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design

1957
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
    The American journal of the medical sciences, 1957, Volume: 233, Issue:3

    Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design

1957
MITRAL INSUFFICIENCY SECONDARY TO RUPTURED CHORDAE TENDINEAE. REPORT OF A SURGICALLY CORRECTED CASE.
    JAMA, 1964, May-18, Volume: 188

    Topics: Cardiac Catheterization; Cardiac Surgical Procedures; Chordae Tendineae; Electrocardiography; Endoca

1964
THE EFFECT OF PROBENECID IN DELAYING THE URINARY EXCRETIONS OF THE NEW PENICILLINS DERIVED FROM 6-AMINOPENICILLANIC ACID.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Ampicillin; Biomedical Research; Blood; Dosage Forms; Endocarditis; Endocarditis, Bacterial; Humans;

1964
ERYSIPELOTHRIX ENDOCARDITIS: REPORT OF A CASE WITH CEREBRAL MANIFESTATIONS.
    JAMA, 1965, Mar-08, Volume: 191

    Topics: Brain Diseases; Chloramphenicol; Chlorothiazide; Digoxin; Diuretics; Drug Therapy; Endocarditis; End

1965
SUBACUTE BACTERIAL ENDOCARDITIS DUE TO HAEMOPHILUS PARAINFLUENZAE.
    The Medical journal of Australia, 1965, May-29, Volume: 1, Issue:22

    Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Drug Therapy; Endocarditis; Endocarditis, Subacute Ba

1965
Benemid in the treatment of streptococcal endocarditis.
    Lancet (London, England), 1952, Jul-05, Volume: 2, Issue:6723

    Topics: Endocarditis; Endocarditis, Subacute Bacterial; Humans; Probenecid

1952
Management of infective endocarditis.
    Journal of the Royal College of Physicians of London, 1981, Volume: 15, Issue:3

    Topics: Amoxicillin; Endocarditis; Humans; Penicillins; Postoperative Complications; Probenecid; Serologic T

1981
Gonorrhea: recommended treatment schedules, 1974 Center for Disease Control.
    Connecticut medicine, 1975, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Drug Therapy, Co

1975
Cephalexin-related nephropathy.
    JAMA, 1975, Nov-10, Volume: 234, Issue:6

    Topics: Administration, Oral; Adult; Cephalexin; Drug Hypersensitivity; Endocarditis; Eosinophilia; Hematuri

1975
The choice of antibiotic for treating infective endocarditis.
    The Quarterly journal of medicine, 1975, Volume: 44, Issue:175

    Topics: Adolescent; Adult; Aged; Amoxicillin; Amphotericin B; Aneurysm, Infected; Anti-Bacterial Agents; Bac

1975
[Factors, affecting penicillin therapy].
    Antibiotiki, 1971, Volume: 16, Issue:6

    Topics: Ampicillin; Anti-Bacterial Agents; Antineoplastic Agents; Bronchitis; Carbenicillin; Cloxacillin; Do

1971