probenecid has been researched along with Endocarditis, Bacterial in 15 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Nevertheless, in individuals who cannot tolerate a high single dose of amoxycillin, there is need for an alternative dosage regimen." | 2.66 | Pharmacokinetic comparison of two models of endocarditis prophylaxis with amoxycillin. ( Höglund, P; Paulsen, O; Schalén, C, 1989) |
| "Extraneous infective endocarditis is most often caused by staphylococci, with Gram-negative bacilli and fungi also quite frequent infecting agents." | 1.25 | The choice of antibiotic for treating infective endocarditis. ( Gray, IR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| NICHOLS, RL | 2 |
| RICHARDS, WA | 2 |
| FINLAND, M | 2 |
| LAPORTE, A | 1 |
| TANZER, J | 1 |
| ROSA, J | 1 |
| ROBINSON, OP | 1 |
| SILBERSTEIN, EB | 1 |
| Shanson, DC | 2 |
| McNabb, R | 1 |
| Hajipieris, P | 1 |
| Pinchas, A | 1 |
| Lessing, J | 1 |
| Siegman-Igra, Y | 1 |
| Liron, M | 1 |
| Chayakul, P | 1 |
| Yipintsoi, T | 1 |
| Gray, IR | 1 |
| Paulsen, O | 1 |
| Höglund, P | 1 |
| Schalén, C | 1 |
| Bartel, J | 1 |
| Kump, J | 1 |
| Moskowitz, J | 1 |
| Ehrenkranz, NJ | 1 |
| Panunzio, Y | 1 |
| Graber, CD | 1 |
| Jervey, LP | 1 |
| Ostrander, WE | 1 |
| Salley, LH | 1 |
| Weaver, RE | 1 |
| Beaty, HN | 1 |
| Turck, M | 1 |
| Petersdorf, RG | 1 |
| Stammberger, K | 1 |
| Fiehring, H | 1 |
| Heimer, I | 1 |
| Sprössig, M | 1 |
1 trial available for probenecid and Endocarditis, Bacterial
| Article | Year |
|---|---|
Pharmacokinetic comparison of two models of endocarditis prophylaxis with amoxycillin.
Topics: Adult; Amoxicillin; Dose-Response Relationship, Drug; Drug Combinations; Endocarditis, Bacterial; Fe | 1989 |
14 other studies available for probenecid and Endocarditis, Bacterial
| Article | Year |
|---|---|
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design | 1957 |
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design | 1957 |
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design | 1957 |
Penicillin and probenecid: a controlled study of penicillin levels in plasma of patients with bacterial endocarditis.
Topics: Endocarditis; Endocarditis, Bacterial; Humans; Penicillins; Plasma; Probenecid; Research Design | 1957 |
[Enhancement of penicillinemia as obtained with dipropylsulfamylbenzoic acid (probenecid, benamid) in three patients treated by a penicillin-streptomycin combination for malignant endocarditis].
Topics: Acute Disease; Endocarditis, Bacterial; Humans; Penicillins; Polycythemia Vera; Probenecid; Stomach; | 1957 |
THE EFFECT OF PROBENECID IN DELAYING THE URINARY EXCRETIONS OF THE NEW PENICILLINS DERIVED FROM 6-AMINOPENICILLANIC ACID.
Topics: Ampicillin; Biomedical Research; Blood; Dosage Forms; Endocarditis; Endocarditis, Bacterial; Humans; | 1964 |
ERYSIPELOTHRIX ENDOCARDITIS: REPORT OF A CASE WITH CEREBRAL MANIFESTATIONS.
Topics: Brain Diseases; Chloramphenicol; Chlorothiazide; Digoxin; Diuretics; Drug Therapy; Endocarditis; End | 1965 |
The effect of probenecid on serum amoxycillin concentrations up to 18 hours after a single 3 g oral dose of amoxycillin: possible implications for preventing endocarditis.
Topics: Administration, Oral; Adult; Amoxicillin; Drug Interactions; Drug Therapy, Combination; Endocarditis | 1984 |
Oral treatment of bacterial endocarditis.
Topics: Administration, Oral; Adult; Aged; Ampicillin; Drug Therapy, Combination; Endocarditis, Bacterial; F | 1983 |
Intravenous followed by oral antimicrobial therapy for staphylococcal endocarditis.
Topics: Administration, Oral; Adult; Aged; Cloxacillin; Dicloxacillin; Drug Administration Schedule; Drug Th | 1993 |
The choice of antibiotic for treating infective endocarditis.
Topics: Adolescent; Adult; Aged; Amoxicillin; Amphotericin B; Aneurysm, Infected; Anti-Bacterial Agents; Bac | 1975 |
Failure of a single dose amoxycillin as prophylaxis against endocarditis.
Topics: Amoxicillin; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Probenecid | 1985 |
[Bacterial heart infections in the child--their relation to sepsis].
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Electrocardiography; Endocarditis, Bacterial; Heart | 1974 |
Cephaloridine in the treatment of streptococcal endocarditis: a preliminary evaluation.
Topics: Adult; Aged; Blood Urea Nitrogen; Cephaloridine; Endocarditis, Bacterial; Enterococcus faecalis; Fem | 1969 |
Endocarditis due to a lanthanic, unclassified Gram-negative bacterium (group IV d).
Topics: Adult; Ampicillin; Bacteria; Chloramphenicol; Endocarditis, Bacterial; Humans; Male; Penicillin G; P | 1968 |
Activity of broad-spectrum antibiotics against enterococci and their efficacy in enterococcal endocarditis.
Topics: Administration, Oral; Ampicillin; Cephaloridine; Cephalothin; Chloramphenicol; Endocarditis, Bacteri | 1967 |
[Clinical-microbiological analysis of 50 patients with bacterial carditis].
Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; Female; Glucocorticoids; Humans; Probenecid; Prognos | 1970 |