probenecid has been researched along with Electrolytes in 11 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetic and pharmacodynamic profiles of oral enalapril (20 mg), in absence and in presence of probenecid pretreatment (1 g twice daily for 5 days), were investigated in 12 healthy volunteers on normal salt intake (150 mmol/24 hr)." | 1.28 | Pharmacokinetic and pharmacodynamic actions of enalapril in humans: effect of probenecid pretreatment. ( Lant, AF; McNabb, WR; Noormohamed, FH, 1990) |
| " A dose-response relationship of torasemide in the range of 0." | 1.27 | Renal effects of torasemide in the rat. Clearance and micropuncture studies. ( Heidenreich, O; Hermes, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BRONSKY, D | 1 |
| DUBIN, A | 1 |
| KUSHNER, DS | 1 |
| CAMPBELL, DE | 1 |
| BERNDT, WO | 1 |
| BEECHWOOD, EC | 1 |
| Odlind, B | 1 |
| Beermann, B | 1 |
| Selén, G | 1 |
| Persson, AE | 1 |
| Rice, WR | 1 |
| Steck, TL | 1 |
| Pardridge, WM | 1 |
| Oldendorf, WH | 1 |
| Nuki, G | 1 |
| Watson, ML | 1 |
| Williams, BC | 1 |
| Simmonds, HA | 1 |
| Wallace, RC | 1 |
| Noormohamed, FH | 1 |
| McNabb, WR | 1 |
| Lant, AF | 1 |
| Hermes, H | 1 |
| Heidenreich, O | 1 |
| Suzuki, Y | 1 |
| Ina, K | 1 |
| Ito, M | 1 |
| Yamagami, I | 1 |
| Fanelli, GM | 1 |
| Bohn, DL | 1 |
| Reilly, SS | 1 |
11 other studies available for probenecid and Electrolytes
| Article | Year |
|---|---|
Diuretic action of benemid; its effect upon the urinary excretion of sodium, chloride, potassium and water in edematous subjects.
Topics: Diuresis; Diuretics; Edema; Electrolytes; Heart Failure; Humans; Kidney Diseases; Potassium; Probene | 1955 |
Modification by bromcresol green or probenecid of urinary excretion of sodium, chloride and potassium due to mercaptomerin.
Topics: Bromcresol Green; Chlorides; Diuretics; Electrolytes; Humans; Ions; Organomercury Compounds; Phenolp | 1960 |
INFLUENCE OF INORGANIC ELECTROLYTES AND OUABAIN ON URIC ACID TRANSPORT.
Topics: Animals; Biological Transport; Cesium; Electrolytes; Ions; Kidney; Ouabain; Pharmacology; Potassium; | 1965 |
Renal tubular secretion of piretanide and its effects on electrolyte reabsorption and tubuloglomerular feedback mechanism.
Topics: Diuretics; Electrolytes; Feedback; Humans; Kidney Glomerulus; Kidney Tubules; Loop of Henle; Nephron | 1983 |
Pyruvate transport into inside-out vesicles isolated from human erythrocyte membranes.
Topics: Biological Transport; Copper; Culture Media; Dinitrofluorobenzene; Electrolytes; Erythrocyte Membran | 1977 |
Transport of metabolic substrates through the blood-brain barrier.
Topics: Amino Acids; Animals; Biogenic Amines; Biological Transport; Blood-Brain Barrier; Carboxylic Acids; | 1977 |
Congenital chloride losing enteropathy associated with tophaceous gouty arthritis.
Topics: Adult; Alkalosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Blood Pressure; Captopr | 1991 |
Pharmacokinetic and pharmacodynamic actions of enalapril in humans: effect of probenecid pretreatment.
Topics: Adult; Blood Pressure; Electrolytes; Enalapril; Enalaprilat; Humans; Kidney; Male; Probenecid | 1990 |
Renal effects of torasemide in the rat. Clearance and micropuncture studies.
Topics: Animals; Diuretics; Electrolytes; Kidney; Kidney Glomerulus; Loop of Henle; Male; Nephrons; Perfusio | 1985 |
[Pharmacological studies of diuretics. 4. Changes of serum uric acid level by the succesive administration of thiazide diuretics and other drugs and effects of uricosuric drugs].
Topics: Administration, Oral; Allopurinol; Ammonium Chloride; Animals; Barbiturates; Blood Glucose; Chloroth | 1971 |
Renal effects of uricosuric agents in the chimpanzee.
Topics: Aminohippuric Acids; Animals; Benzoates; Benzyl Compounds; Chlorothiazide; Electrolytes; Glomerular | 1971 |