probenecid has been researched along with Dystonia in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The severity of dystonia in these mutant hamsters was significantly reduced by NBQX at doses of 10-20 mg/kg i." | 1.29 | The AMPA receptor antagonist NBQX exerts antidystonic effects in an animal model of idiopathic dystonia. ( Löscher, W; Löschmann, PA; Richter, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richter, A | 1 |
| Löscher, W | 1 |
| Löschmann, PA | 1 |
1 other study available for probenecid and Dystonia
| Article | Year |
|---|---|
The AMPA receptor antagonist NBQX exerts antidystonic effects in an animal model of idiopathic dystonia.
Topics: Animals; Cricetinae; Dystonia; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Inje | 1993 |