probenecid has been researched along with Diarrhea in 6 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A breast-fed infant of a 30-year-old woman being treated with oral probenecid and cephalexin for a breast infection developed severe diarrhea and associated symptoms." | 3.73 | Transfer of probenecid and cephalexin into breast milk. ( Bretz, PJ; Hackett, LP; Ilett, KF; Ingle, B, 2006) |
| "Bacampicillin was well tolerated in all treatment groups." | 2.65 | A dose response study with bacampicillin in uncomplicated gonorrhoea. ( Bengtsson, S; Eriksson, G; Kallings, LO; Sandström, E; Wallin, J; Wallmark, G, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokooji, T | 1 |
| Kawabe, Y | 1 |
| Mori, N | 1 |
| Murakami, T | 1 |
| Ilett, KF | 1 |
| Hackett, LP | 1 |
| Ingle, B | 1 |
| Bretz, PJ | 1 |
| Wallin, J | 1 |
| Bengtsson, S | 1 |
| Eriksson, G | 1 |
| Kallings, LO | 1 |
| Sandström, E | 1 |
| Wallmark, G | 1 |
| Kates, RE | 1 |
| Tozer, TN | 1 |
| Sorby, DL | 1 |
| Nuki, G | 1 |
| Watson, ML | 1 |
| Williams, BC | 1 |
| Simmonds, HA | 1 |
| Wallace, RC | 1 |
| Mitchell, RW | 1 |
| Robson, HG | 1 |
1 trial available for probenecid and Diarrhea
| Article | Year |
|---|---|
A dose response study with bacampicillin in uncomplicated gonorrhoea.
Topics: Administration, Oral; Ampicillin; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Dr | 1979 |
5 other studies available for probenecid and Diarrhea
| Article | Year |
|---|---|
Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats.
Topics: Alkaline Phosphatase; Animals; Biliary Tract; Body Weight; Camptothecin; Diarrhea; Drug Interactions | 2013 |
Transfer of probenecid and cephalexin into breast milk.
Topics: Adult; Anti-Bacterial Agents; Breast Feeding; Cephalexin; Diarrhea; Drug Therapy, Combination; Femal | 2006 |
Increased methotrexate toxicity due to concurrent probenecid administration.
Topics: Animals; Bile; Diarrhea; Drug Synergism; Male; Methotrexate; Probenecid; Rats; Time Factors | 1976 |
Congenital chloride losing enteropathy associated with tophaceous gouty arthritis.
Topics: Adult; Alkalosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Blood Pressure; Captopr | 1991 |
Comparison of amoxicillin and ampicillin in single-dose oral treatment of males with gonococcal urethritis.
Topics: Administration, Oral; Amines; Ampicillin; Diarrhea; Drug Evaluation; Follow-Up Studies; Gonorrhea; H | 1974 |