probenecid has been researched along with Diabetes Mellitus in 7 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gout has significant impact on the quality of life with over-utilisation of health resources." | 1.56 | Burden and management of gout in a multi-ethnic Asian cohort. ( Cheung, PP; Chua, CKT; Lim, AYN; Santosa, A; Teng, GG, 2020) |
| "Gout is increasingly recognized as the most common form of inflammatory arthritis worldwide; however, no Canadian data on the disease burden of gout are available." | 1.46 | The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012. ( Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K, 2017) |
| "Patients with gout have comorbidities, but the impact of these comorbidities on treatment has not been studied." | 1.37 | Prevalence of contraindications and prescription of pharmacologic therapies for gout. ( Crittenden, DB; Fisher, MC; Goldfarb, DS; Keenan, RT; Krasnokutsky, S; Lee, KH; O'Brien, WR; Oh, C; Pillinger, MH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chua, CKT | 1 |
| Cheung, PP | 1 |
| Santosa, A | 1 |
| Lim, AYN | 1 |
| Teng, GG | 1 |
| Rai, SK | 1 |
| Aviña-Zubieta, JA | 1 |
| McCormick, N | 1 |
| De Vera, MA | 1 |
| Shojania, K | 1 |
| Sayre, EC | 1 |
| Choi, HK | 1 |
| Keenan, RT | 1 |
| O'Brien, WR | 1 |
| Lee, KH | 1 |
| Crittenden, DB | 1 |
| Fisher, MC | 1 |
| Goldfarb, DS | 1 |
| Krasnokutsky, S | 1 |
| Oh, C | 1 |
| Pillinger, MH | 1 |
| Hirai, A | 1 |
| Saito, Y | 1 |
| McMahon, FG | 1 |
| Ryan, JR | 1 |
| Jain, AK | 1 |
| Kusus, T | 1 |
| Lydtin, H | 1 |
| Zöllner, N | 1 |
| Duncan, GG | 1 |
| Duncan, TG | 1 |
| Schatanoff, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ACTH vs Betamethasone for the Treatment of Acute Gout in Hospitalized Patients: A Randomized, Open Label, Comparative Study[NCT04306653] | 60 participants (Anticipated) | Interventional | 2018-01-05 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for probenecid and Diabetes Mellitus
| Article | Year |
|---|---|
[Management of hyperuricemia in diabetes].
Topics: Allopurinol; Benzbromarone; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Human | 1997 |
3 trials available for probenecid and Diabetes Mellitus
| Article | Year |
|---|---|
The hypouricaemic effect of tienilic acid: experience in patients with hyperuricaemia.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Drug A | 1979 |
[Saluretic treatment of hypertension and uric acid level in serum. Clinical test of a combination of hydrochlorothiazide and probenecid].
Topics: Adult; Aged; Alanine Transaminase; Blood Glucose; Blood Pressure; Blood Protein Electrophoresis; Bod | 1969 |
Refractory obesity and diabetes.
Topics: Adult; Body Weight; Diabetes Mellitus; Diet, Diabetic; Fasting; Female; Glucose Tolerance Test; Huma | 1968 |
3 other studies available for probenecid and Diabetes Mellitus
| Article | Year |
|---|---|
Burden and management of gout in a multi-ethnic Asian cohort.
Topics: Adult; Aged; Allopurinol; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Dyslipidemias; Em | 2020 |
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012.
Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidit | 2017 |
Prevalence of contraindications and prescription of pharmacologic therapies for gout.
Topics: Aged; Aged, 80 and over; Allopurinol; Colchicine; Comorbidity; Contraindications; Diabetes Mellitus; | 2011 |