probenecid has been researched along with Demyelinating Diseases in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid is a pannexin-1 antagonist and a probenecid therapy was investigated." | 1.46 | Probenecid-treatment reduces demyelination induced by cuprizone feeding. ( Becker, P; Beisswenger, C; Hainz, N; Meier, C; Rapp, D; Tschernig, T; Wagenpfeil, S; Wonnenberg, B, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hainz, N | 1 |
| Becker, P | 1 |
| Rapp, D | 1 |
| Wagenpfeil, S | 1 |
| Wonnenberg, B | 1 |
| Beisswenger, C | 1 |
| Tschernig, T | 1 |
| Meier, C | 1 |
| Sonninen, V | 1 |
| Riekkinen, P | 1 |
| Rinne, UK | 1 |
2 other studies available for probenecid and Demyelinating Diseases
| Article | Year |
|---|---|
Probenecid-treatment reduces demyelination induced by cuprizone feeding.
Topics: Animals; Cuprizone; Demyelinating Diseases; Diet; Disease Models, Animal; Leukocytes; Lymphocytes; M | 2017 |
Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
Topics: Acute Disease; Adult; Brain; Chronic Disease; Demyelinating Diseases; Female; Homovanillic Acid; Hum | 1973 |