probenecid has been researched along with Cochlear Diseases in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Cochlear Diseases: Pathological processes of the snail-like structure (COCHLEA) of the inner ear (LABYRINTH) which can involve its nervous tissue, blood vessels, or fluid (ENDOLYMPH).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Furosemide is a loop diuretic which is ototoxic." | 5.28 | Effects of organic acids on the edema of the stria vascularis induced by furosemide. ( Rybak, LP; Scott, V; Weberg, A; Whitworth, C, 1992) |
| "Traditional treatment of otosyphilis with penicillin and corticosteroids has achieved hearing improvement; however, selecting which patients with a positive fluorescent treponemal antibody absorption (FTA-ABS) test will benefit from treatment remains a problem." | 2.67 | Otosyphilis: a diagnostic and therapeutic dilemma. ( Gleich, LL; Kimmelman, CP; Linstrom, CJ, 1992) |
| "Furosemide is a loop diuretic which is ototoxic." | 1.28 | Effects of organic acids on the edema of the stria vascularis induced by furosemide. ( Rybak, LP; Scott, V; Weberg, A; Whitworth, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gleich, LL | 1 |
| Linstrom, CJ | 1 |
| Kimmelman, CP | 1 |
| Rybak, LP | 1 |
| Whitworth, C | 1 |
| Weberg, A | 1 |
| Scott, V | 1 |
1 trial available for probenecid and Cochlear Diseases
| Article | Year |
|---|---|
Otosyphilis: a diagnostic and therapeutic dilemma.
Topics: Adult; Aged; Amoxicillin; Cardiolipins; Cerebrospinal Fluid; Cholesterol; Clinical Protocols; Cochle | 1992 |
1 other study available for probenecid and Cochlear Diseases
| Article | Year |
|---|---|
Effects of organic acids on the edema of the stria vascularis induced by furosemide.
Topics: Acids; Animals; Cochlear Diseases; Edema; Evoked Potentials, Auditory; Furosemide; Microscopy, Elect | 1992 |