probenecid has been researched along with Choriocarcinoma in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanism of transport of 5-methyltetrahydrofolate, the predominant form of folate in human blood, was investigated in JAR human placental choriocarcinoma cells." | 7.69 | Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells. ( Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD, 1994) |
| "The mechanism of transport of 5-methyltetrahydrofolate, the predominant form of folate in human blood, was investigated in JAR human placental choriocarcinoma cells." | 3.69 | Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells. ( Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gravett, PJ | 1 |
| Borthwick-Clarke, C | 1 |
| Prasad, PD | 1 |
| Mahesh, VB | 1 |
| Leibach, FH | 1 |
| Ganapathy, V | 1 |
2 other studies available for probenecid and Choriocarcinoma
| Article | Year |
|---|---|
The use of granulocyte transfusion: a case report.
Topics: Adult; Blood Transfusion; Choriocarcinoma; Female; Granulocytes; Humans; Methotrexate; Military Medi | 1980 |
Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells.
Topics: Anti-Bacterial Agents; Base Sequence; Carrier Proteins; Choriocarcinoma; Female; Folate Receptors, G | 1994 |