probenecid has been researched along with Chorea in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Homovanilic acid (HVA) was determined in the lumbar CSF of 12 patients with Huntington's disease and 12 with Sydenham's chorea before and after probenecid administration." | 3.66 | Homovanilic acid in Huntington's disease and Sydenham's chorea. ( Amaral, R; Conçalves, AF; Cunha, L; Diniz, M; Oliveira, CR; Pio-Abreu, J, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michener, WM | 1 |
| Cunha, L | 1 |
| Oliveira, CR | 1 |
| Diniz, M | 1 |
| Amaral, R | 1 |
| Conçalves, AF | 1 |
| Pio-Abreu, J | 1 |
2 other studies available for probenecid and Chorea
| Article | Year |
|---|---|
Hyperuricemia and mental retardation with athetosis and self-mutilation.
Topics: Allopurinol; Athetosis; Body Height; Body Weight; Child; Child, Preschool; Chorea; Humans; Infant; I | 1967 |
Homovanilic acid in Huntington's disease and Sydenham's chorea.
Topics: Adult; Chorea; Female; Homovanillic Acid; Humans; Huntington Disease; Male; Middle Aged; Phenylaceta | 1981 |