probenecid has been researched along with Chlamydia Infections in 13 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Chlamydia Infections: Infections with bacteria of the genus CHLAMYDIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicenter randomized comparative trial was done to assess the safety and efficacy of oral ofloxacin (400 mg twice daily for 10 days) versus cefoxitin (2 g intramuscularly) followed by doxycycline (100 mg twice daily orally for 10 days) for the outpatient treatment of uncomplicated pelvic inflammatory disease (PID)." | 9.07 | Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group. ( Berkeley, A; Binder, D; Faro, S; Gordon, S; Martens, MG; Yarborough, DR, 1993) |
| "The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis." | 9.07 | A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991) |
| "A multicenter randomized comparative trial was done to assess the safety and efficacy of oral ofloxacin (400 mg twice daily for 10 days) versus cefoxitin (2 g intramuscularly) followed by doxycycline (100 mg twice daily orally for 10 days) for the outpatient treatment of uncomplicated pelvic inflammatory disease (PID)." | 5.07 | Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group. ( Berkeley, A; Binder, D; Faro, S; Gordon, S; Martens, MG; Yarborough, DR, 1993) |
| "The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis." | 5.07 | A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991) |
| "Each of 201 men with symptoms and signs of acute urethritis was randomly assigned to one of two treatment regimens: ampicillin (2g) plus probenecid (1g), or sulphamethoxazole-trimethoprim (SMX-TMP) (sulphamethoxazole 1600 mg plus trimethoprim 320 mg) four tablets twice daily for two days." | 5.05 | Treatment of acute gonococcal urethritis in men with simultaneous infection with Chlamydia trachomatis. ( Bjerk, O; Csángó, PA; Gundersen, T; Jagars, G; Salveson, A, 1984) |
| " Thus ampicillin plus probencide in the dosage used rarely eliminated C." | 1.26 | The lack of effect of ampicillin plus probenecid given for genital infections with Neisseria gonorrhoeae on associated infections with Chlamydia trachomatis. ( Beckingham, DC; Oriel, JD; Owen, J; Reeve, P; Ridgway, GL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKuen, MJ | 1 |
| Dahl, G | 1 |
| Fields, KA | 1 |
| Haggerty, CL | 1 |
| Ness, RB | 1 |
| Amortegui, A | 1 |
| Hendrix, SL | 1 |
| Hillier, SL | 1 |
| Holley, RL | 1 |
| Peipert, J | 1 |
| Randall, H | 1 |
| Sondheimer, SJ | 1 |
| Soper, DE | 1 |
| Sweet, RL | 1 |
| Trucco, G | 1 |
| Csángó, PA | 1 |
| Salveson, A | 1 |
| Gundersen, T | 1 |
| Jagars, G | 1 |
| Bjerk, O | 1 |
| Welch, RD | 1 |
| Fletcher, DJ | 1 |
| Nelson, JH | 1 |
| Blackwell, M | 1 |
| Fergerson, J | 1 |
| Ridgway, GL | 2 |
| Oriel, JD | 2 |
| Martens, MG | 1 |
| Gordon, S | 1 |
| Yarborough, DR | 1 |
| Faro, S | 1 |
| Binder, D | 1 |
| Berkeley, A | 1 |
| Sherrard, J | 1 |
| Barlow, D | 1 |
| Reeve, P | 1 |
| Beckingham, DC | 1 |
| Owen, J | 1 |
| Wendel, GD | 1 |
| Cox, SM | 1 |
| Bawdon, RE | 1 |
| Theriot, SK | 1 |
| Heard, MC | 1 |
| Nobles, BJ | 1 |
| Lassus, A | 1 |
| Karppinen, L | 1 |
| Ingervo, L | 1 |
| Jeskanen, L | 1 |
| Reitamo, S | 1 |
| Happonen, HP | 1 |
| Karkulahti, R | 1 |
| Black, JR | 1 |
| Long, JM | 1 |
| Zwickl, BE | 1 |
| Ray, BS | 1 |
| Verdon, MS | 1 |
| Wetherby, S | 1 |
| Hook, EW | 2 |
| Handsfield, HH | 2 |
| Roddy, RE | 1 |
| Rompalo, AM | 1 |
| Roberts, P | 1 |
| Johnson, K | 1 |
| Stamm, WE | 1 |
8 trials available for probenecid and Chlamydia Infections
| Article | Year |
|---|---|
Endometritis does not predict reproductive morbidity after pelvic inflammatory disease.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Cefoxitin; Chla | 2003 |
Treatment of acute gonococcal urethritis in men with simultaneous infection with Chlamydia trachomatis.
Topics: Acute Disease; Ampicillin; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia trachomat | 1984 |
Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group.
Topics: Adolescent; Adult; Ambulatory Care; Cefoxitin; Chlamydia Infections; Chlamydia trachomatis; Doxycycl | 1993 |
A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis.
Topics: Acute Disease; Adult; Ambulatory Care; Cefoxitin; Chi-Square Distribution; Chlamydia Infections; Chl | 1991 |
Ciprofloxacin versus amoxycillin and probenecid in the treatment of uncomplicated gonorrhoea.
Topics: Adolescent; Adult; Amoxicillin; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Drug Com | 1989 |
Multicenter randomized study of single-dose ofloxacin versus amoxicillin-probenecid for treatment of uncomplicated gonococcal infection.
Topics: Adult; Amoxicillin; Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Male; Mi | 1989 |
Comparative trial of single-dose ciprofloxacin and ampicillin plus probenecid for treatment of gonococcal urethritis in men.
Topics: Adolescent; Adult; Ampicillin; Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Clinical | 1986 |
Empirical therapy for the management of acute proctitis in homosexual men.
Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Doxycycline; Drug Therapy, Combinati | 1988 |
5 other studies available for probenecid and Chlamydia Infections
| Article | Year |
|---|---|
Assessing a potential role of host Pannexin 1 during Chlamydia trachomatis infection.
Topics: Animals; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Connexins; HeLa Cells; | 2013 |
Current treatment approaches for gonorrhea in men: two for the price of one.
Topics: Administration, Oral; Adolescent; Adult; Chlamydia Infections; Drug Therapy, Combination; Gonorrhea; | 1984 |
Advantages of adding a course of tetracycline to single dose ampicillin and probenecid in the treatment of gonorrhoea.
Topics: Ampicillin; Chlamydia Infections; Chlamydia trachomatis; Drug Combinations; Drug Therapy, Combinatio | 1984 |
Gonorrhoea in men: clinical and diagnostic aspects.
Topics: Adolescent; Adult; Aged; Ampicillin; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachoma | 1996 |
The lack of effect of ampicillin plus probenecid given for genital infections with Neisseria gonorrhoeae on associated infections with Chlamydia trachomatis.
Topics: Ampicillin; Chlamydia Infections; Chlamydia trachomatis; Drug Therapy, Combination; Female; Gonorrhe | 1976 |