probenecid has been researched along with Central Nervous System Diseases in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Regimens accepted for the treatment of neurosyphilis appear to be adequate for the treatment of ocular syphilis in HIV-1-infected patients though further long-term follow-up will be required." | 1.28 | The ocular manifestations of syphilis in the human immunodeficiency virus type 1-infected host. ( Culbertson, WW; Holland, S; McLeish, WM; Pulido, JS; Winward, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, H | 1 |
| Lerner, PI | 1 |
| Weinstein, L | 1 |
| McLeish, WM | 1 |
| Pulido, JS | 1 |
| Holland, S | 1 |
| Culbertson, WW | 1 |
| Winward, K | 1 |
| Chase, TN | 1 |
3 other studies available for probenecid and Central Nervous System Diseases
| Article | Year |
|---|---|
Neurotoxicity and "massive" intravenous therapy with penicillin. A study of possible predisposing factors.
Topics: Adolescent; Adult; Aged; Central Nervous System; Central Nervous System Diseases; Child; Child, Pres | 1967 |
The ocular manifestations of syphilis in the human immunodeficiency virus type 1-infected host.
Topics: Adult; Central Nervous System Diseases; Doxycycline; Eye Diseases; Fundus Oculi; HIV Infections; HIV | 1990 |
Central monoamine metabolism in man. Effect of putative dopamine receptor agonists and antagonists.
Topics: Adult; Basal Ganglia Diseases; Brain; Central Nervous System Diseases; Dopamine; Haloperidol; Homova | 1973 |