probenecid has been researched along with Cardiomyopathies in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid has been used for decades in the treatment of gout but recently has also been found to improve outcomes in patients with heart failure via stimulation of the transient receptor potential vanilloid 2 (TRPV2) channel in cardiomyocytes." | 3.96 | Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy. ( Koch, SE; Kranias, EG; Liu, G; McDermott, MR; Onusko, E; Robbins, N; Rubinstein, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Onusko, E | 1 |
| McDermott, MR | 1 |
| Robbins, N | 1 |
| Liu, G | 1 |
| Kranias, EG | 1 |
| Rubinstein, J | 1 |
| Koch, SE | 1 |
1 other study available for probenecid and Cardiomyopathies
| Article | Year |
|---|---|
Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy.
Topics: Animals; Apoptosis; Calcium Channels; Cardiomyopathies; Disease Models, Animal; Echocardiography; Fe | 2020 |