probenecid has been researched along with Cardiomegaly in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid was also detected in vitreous and bile." | 1.28 | A death involving probenecid. ( Crump, K; Drummer, OH; McIntyre, IM; Roberts, AN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McIntyre, IM | 1 |
| Crump, K | 1 |
| Roberts, AN | 1 |
| Drummer, OH | 1 |
1 other study available for probenecid and Cardiomegaly
| Article | Year |
|---|---|
A death involving probenecid.
Topics: Adult; Alcohol Drinking; Bile; Cardiomegaly; Drug Overdose; Ethanol; Humans; Liver; Male; Probenecid | 1992 |