probenecid has been researched along with Cardiac Output, Low in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Allopurinol has been shown to improve endothelial function in chronic heart failure." | 2.72 | High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid. ( Belch, JJ; Carr, E; Davies, J; George, J; Struthers, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| George, J | 1 |
| Carr, E | 1 |
| Davies, J | 1 |
| Belch, JJ | 1 |
| Struthers, A | 1 |
1 trial available for probenecid and Cardiac Output, Low
| Article | Year |
|---|---|
High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid.
Topics: Acetylcholine; Aged; Allopurinol; Ascorbic Acid; Blood Pressure; Cardiac Output, Low; Cross-Over Stu | 2006 |