probenecid has been researched along with Cardiac Hypertrophy in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid was also detected in vitreous and bile." | 1.28 | A death involving probenecid. ( Crump, K; Drummer, OH; McIntyre, IM; Roberts, AN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McIntyre, IM | 1 |
| Crump, K | 1 |
| Roberts, AN | 1 |
| Drummer, OH | 1 |
1 other study available for probenecid and Cardiac Hypertrophy
| Article | Year |
|---|---|
A death involving probenecid.
Topics: Adult; Alcohol Drinking; Bile; Cardiomegaly; Drug Overdose; Ethanol; Humans; Liver; Male; Probenecid | 1992 |