probenecid has been researched along with Carcinoma, Ehrlich Tumor in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fry, DW | 1 |
| Yalowich, JC | 1 |
| Goldman, ID | 1 |
| Sirotnak, FM | 1 |
| Moccio, DM | 1 |
| Young, CW | 1 |
| Gewirtz, DA | 1 |
| Holt, SA | 1 |
3 other studies available for probenecid and Carcinoma, Ehrlich Tumor
| Article | Year |
|---|---|
Augmentation of the intracellular levels of polyglutamyl derivatives of methotrexate by vincristine and probenecid in Ehrlich ascites tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; In Vitro Techniques; Male; Methotrexate; Mice; Mice, Inbred BALB | 1982 |
Increased accumulation of methotrexate by murine tumor cells in vitro in the presence of probenecid which is mediated by a preferential inhibition of efflux.
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Leukemia L1210; Methotrexate; Mice; Neoplas | 1981 |
Protein binding as a component of drug interaction in cellular pharmacokinetic studies. Effects of probenecid on transport and accumulation of methotrexate in Ehrlich ascites tumor cells in vitro.
Topics: Animals; Biological Transport; Blood Proteins; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, | 1985 |