probenecid has been researched along with Cancer of Prostate in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 3D-cultured prostate cancer cells, probenecid demonstrated pleiotropic effects such as chemosensitization, growth suppression, inhibition of spheroid compaction, and suppression of anchorage-independent growth." | 1.62 | Pleiotropic effects of probenecid on three-dimensional cultures of prostate cancer cells. ( Fujii, M; Islam, MS; Kamoto, T; Mukai, S; Nagai, T; Nakazawa, H; Taniguchi, T; Terada, N; Uwada, J; Yamasaki, K; Yazawa, T, 2021) |
| "A hallmark of prostate cancer progression is activin insensitivity; however, mechanisms underlying this are unclear." | 1.43 | Uric acid: a modulator of prostate cells and activin sensitivity. ( Bahn, A; Gold, E; Rodrigues, E; Sangkop, F; Singh, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Uwada, J | 1 |
| Mukai, S | 1 |
| Terada, N | 1 |
| Nakazawa, H | 1 |
| Islam, MS | 1 |
| Nagai, T | 1 |
| Fujii, M | 1 |
| Yamasaki, K | 1 |
| Taniguchi, T | 1 |
| Kamoto, T | 1 |
| Yazawa, T | 1 |
| Sangkop, F | 1 |
| Singh, G | 1 |
| Rodrigues, E | 1 |
| Gold, E | 1 |
| Bahn, A | 1 |
| Horne, DW | 1 |
| Reed, KA | 1 |
3 other studies available for probenecid and Cancer of Prostate
| Article | Year |
|---|---|
Pleiotropic effects of probenecid on three-dimensional cultures of prostate cancer cells.
Topics: Antineoplastic Agents; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Humans | 2021 |
Uric acid: a modulator of prostate cells and activin sensitivity.
Topics: Activins; Cell Line, Tumor; Glucose Transport Proteins, Facilitative; Humans; Male; Probenecid; Pros | 2016 |
Transport of methotrexate into LNCaP human prostate cancer cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Biological Transport; Humans; Hydrogen-Ion Concent | 2002 |