Page last updated: 2024-11-03

probenecid and Calcinosis

probenecid has been researched along with Calcinosis in 12 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Calcinosis: Pathologic deposition of calcium salts in tissues.

Research Excerpts

ExcerptRelevanceReference
"To report the efficacy of probenecid for calcinosis of juvenile dermatomyositis (JDM) and assess the changes in phosphorus metabolism during treatment."7.71Treatment of calcinosis in juvenile dermatomyositis with probenecid: the role of phosphorus metabolism in the development of calcifications. ( Amir, J; Harel, G; Harel, L; Korenreich, L; Straussberg, R, 2001)
"Seven year old boy with calcinosis universalis associated with high serum phosphorus was reported."7.67[Calcinosis universalis with hyperphosphataemia--successful treatment with phosphorus deprivation]. ( Amagai, H; Hosokawa, O; Kamimaki, Y; Ono, A; Shoji, T; Takematsu, H; Yoshikawa, S, 1985)
"Childhood dermatomyositis is frequently complicated by deposition of calcium salts in the soft tissues."6.65Calcinosis in dermatomyositis treated with probenecid. ( Haavik, TK; Skuterud, E; Sydnes, OA, 1981)
"Probenecid was used to reduce calcinosis, resulting in remarkable improvement of calcinosis accompanied by normalization of serum phosphorus level and disability after 17 months of administration."5.33Efficacy of probenecid for a patient with juvenile dermatomyositis complicated with calcinosis. ( Eguchi, K; Ejima, E; Ida, H; Kawakami, A; Nakamura, H; Origuchi, T, 2006)
"Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism."4.77Hyperuricemia and gout. ( German, DC; Holmes, EW, 1986)
"To report the efficacy of probenecid for calcinosis of juvenile dermatomyositis (JDM) and assess the changes in phosphorus metabolism during treatment."3.71Treatment of calcinosis in juvenile dermatomyositis with probenecid: the role of phosphorus metabolism in the development of calcifications. ( Amir, J; Harel, G; Harel, L; Korenreich, L; Straussberg, R, 2001)
"Seven year old boy with calcinosis universalis associated with high serum phosphorus was reported."3.67[Calcinosis universalis with hyperphosphataemia--successful treatment with phosphorus deprivation]. ( Amagai, H; Hosokawa, O; Kamimaki, Y; Ono, A; Shoji, T; Takematsu, H; Yoshikawa, S, 1985)
"Childhood dermatomyositis is frequently complicated by deposition of calcium salts in the soft tissues."2.65Calcinosis in dermatomyositis treated with probenecid. ( Haavik, TK; Skuterud, E; Sydnes, OA, 1981)
"Probenecid was used to reduce calcinosis, resulting in remarkable improvement of calcinosis accompanied by normalization of serum phosphorus level and disability after 17 months of administration."1.33Efficacy of probenecid for a patient with juvenile dermatomyositis complicated with calcinosis. ( Eguchi, K; Ejima, E; Ida, H; Kawakami, A; Nakamura, H; Origuchi, T, 2006)
"Treatment with probenecid and intra-arterial injection of reserpine resulted in considerable improvement."1.26Treatment of calcinosis circumscripta and Raynaud's phenomenon. ( Meyers, D, 1976)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TALBOT, FJ1
Nakamura, H1
Kawakami, A1
Ida, H1
Ejima, E1
Origuchi, T1
Eguchi, K1
Skuterud, E1
Sydnes, OA1
Haavik, TK1
Eddy, MC1
Leelawattana, R1
McAlister, WH1
Whyte, MP1
Harel, L1
Harel, G1
Korenreich, L1
Straussberg, R1
Amir, J1
Meyers, D1
German, DC1
Holmes, EW1
Yoshikawa, S1
Shoji, T1
Ono, A1
Amagai, H1
Kamimaki, Y1
Takematsu, H1
Hosokawa, O1
Van Woert, MH1
Weintraub, MI1
Dent, CE1
Stamp, TC1
MacKie, R1
Carroll, KF1
Long, FL1
Smith, RB1

Reviews

1 review available for probenecid and Calcinosis

ArticleYear
Hyperuricemia and gout.
    The Medical clinics of North America, 1986, Volume: 70, Issue:2

    Topics: Acute Disease; Adult; Allopurinol; Anti-Inflammatory Agents; Arthritis; Arthrography; Calcinosis; Ch

1986

Trials

1 trial available for probenecid and Calcinosis

ArticleYear
Calcinosis in dermatomyositis treated with probenecid.
    Scandinavian journal of rheumatology, 1981, Volume: 10, Issue:2

    Topics: Calcinosis; Child; Clinical Trials as Topic; Dermatomyositis; Female; Humans; Probenecid

1981

Other Studies

10 other studies available for probenecid and Calcinosis

ArticleYear
PROPRIETARY DRUG ABUSE; REPORT OF A PROBABLE CASE OF BURNETT'S SYNDROME DUE TO EXCESSIVE INGESTION OF AN OVER-THE-COUNTER REMEDY, TUMS.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Alkalosis; Anemia; Antacids; Blood Transfusion; Calcinosis; Carbonates; Colchicine; Humans; Hypercal

1964
Efficacy of probenecid for a patient with juvenile dermatomyositis complicated with calcinosis.
    The Journal of rheumatology, 2006, Volume: 33, Issue:8

    Topics: Anti-Inflammatory Agents; Calcinosis; Child; Cyclosporine; Dermatomyositis; Drug Therapy, Combinatio

2006
Calcinosis universalis complicating juvenile dermatomyositis: resolution during probenecid therapy.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Adult; Bone Density; Calcinosis; Dermatomyositis; Glomerular Filtration Rate; Humans; L-Lactate Dehy

1997
Treatment of calcinosis in juvenile dermatomyositis with probenecid: the role of phosphorus metabolism in the development of calcifications.
    The Journal of rheumatology, 2001, Volume: 28, Issue:5

    Topics: Calcinosis; Calcium; Child; Dermatomyositis; Female; Humans; Phosphorus; Probenecid; Radiography; Ur

2001
Treatment of calcinosis circumscripta and Raynaud's phenomenon.
    The Medical journal of Australia, 1976, Sep-18, Volume: 2, Issue:12

    Topics: Calcinosis; Female; Humans; Middle Aged; Probenecid; Raynaud Disease; Reserpine

1976
[Calcinosis universalis with hyperphosphataemia--successful treatment with phosphorus deprivation].
    Nihon Seikeigeka Gakkai zasshi, 1985, Volume: 59, Issue:3

    Topics: Aluminum Hydroxide; Bone and Bones; Calcinosis; Child; Connective Tissue Diseases; Humans; Knee Join

1985
Predicting the response to levodopa.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Calcinosis; Capillaries; Central Nervous System; Cerebrospinal Fluid; Cerebrovascular Disorders; Dih

1971
Treatment of calcinosis circumscripta with probenecid.
    British medical journal, 1972, Jan-22, Volume: 1, Issue:5794

    Topics: Adult; Calcinosis; Calcium; Edetic Acid; Female; Fingers; Humans; Joint Diseases; Phosphates; Proben

1972
Probenecid in calcification of the hands.
    British medical journal, 1972, Jun-24, Volume: 2, Issue:5816

    Topics: Calcinosis; Calcium; Female; Hand; Humans; Middle Aged; Probenecid; Scleroderma, Systemic

1972
Complications in a patient with subacute bacterial endocarditis with particular reference to massive penicillin therapy.
    The Medical journal of Australia, 1969, Jun-21, Volume: 1, Issue:25

    Topics: Blood Protein Electrophoresis; Calcinosis; Embolism; Endocarditis, Subacute Bacterial; Femoral Arter

1969