probenecid has been researched along with Brain Swelling in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)." | 5.27 | Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986) |
| "A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)." | 1.27 | Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, XX | 1 |
| Gu, LJ | 1 |
| Shen, J | 1 |
| Kang, XH | 1 |
| Zheng, YY | 1 |
| Yue, SB | 1 |
| Zhu, SM | 1 |
| Gamache, DA | 1 |
| Ellis, EF | 1 |
2 other studies available for probenecid and Brain Swelling
| Article | Year |
|---|---|
Probenecid protects against transient focal cerebral ischemic injury by inhibiting HMGB1 release and attenuating AQP4 expression in mice.
Topics: Animals; Aquaporin 4; Astrocytes; Brain Edema; Brain Injuries; Cerebral Infarction; Down-Regulation; | 2014 |
Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Capillary Permeability; Carrageenan; Cerebrovascular | 1986 |