probenecid has been researched along with Body Weight in 29 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "CSF concentrations of serotonin and dopamine metabolites in 16 patients with anorexia nervosa were measured before and after probenecid administration, and the patients were studied before and at intervals after weight recovery." | 3.67 | Differences in brain serotonergic metabolism between nonbulimic and bulimic patients with anorexia nervosa. ( Ebert, MH; Gwirtsman, HE; Kaye, WH; Weiss, SR, 1984) |
| " Probenecid pretreatment led to a reduction in Tris-BP and Bis-BP tubular necrosis, these effects may be related to inhibition of Bis-BP uptake in the kidney." | 3.67 | Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat. ( Dahl, JE; Dybing, E; Nelson, SD; Omichinski, JG; Søderlund, EJ, 1988) |
| "Pretreatment with probenecid (240 mg kg-1 body weight) potentiated the hyperglycaemic effect of frusemide (25 or 200 mg kg-1 body weight)." | 1.27 | Probenecid potentiates the hyperglycaemic effect but reduces the diuretic effect of frusemide in mice. ( Sandström, PE, 1986) |
| "Probenecid pretreatment did not decrease the toxicity of BH4." | 1.27 | The toxicity of tetrahydrobiopterin: acute and subchronic studies in mice. ( Combs, AB; Folkers, K; Lewandowski, EM, 1986) |
| "Thus, in pyridoxine deficiency one would expect a decrease of serotonin as well as the catecholamines of the brain." | 1.26 | Nonparallel changes in brain monoamines of pyridoxine-deficient growing rats. ( Dakshinamurti, K; Havlicek, V; Herchl, R; LeBlancq, WD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (82.76) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janakiraman, U | 1 |
| Manivasagam, T | 1 |
| Justin Thenmozhi, A | 1 |
| Dhanalakshmi, C | 1 |
| Essa, MM | 1 |
| Song, BJ | 1 |
| Guillemin, GJ | 1 |
| Dorajoo, Rs | 1 |
| Pereira, BP | 1 |
| Yu, Z | 1 |
| Gopalakrishnakone, P | 1 |
| Leong, CC | 1 |
| Wee, A | 1 |
| Lee, E | 1 |
| Yokooji, T | 1 |
| Kawabe, Y | 1 |
| Mori, N | 1 |
| Murakami, T | 1 |
| McAnulty, SR | 1 |
| Hosick, PA | 1 |
| McAnulty, LS | 1 |
| Quindry, JC | 1 |
| Still, L | 1 |
| Hudson, MB | 1 |
| Dibarnardi, AN | 1 |
| Milne, GL | 1 |
| Morrow, JD | 1 |
| Austin, MD | 1 |
| Michener, WM | 1 |
| Jakovcic, S | 1 |
| Sorensen, LB | 1 |
| Leprohon, CE | 1 |
| Anderson, GH | 1 |
| Fuenmayor, LD | 1 |
| García, S | 1 |
| Kaye, WH | 1 |
| Ebert, MH | 1 |
| Gwirtsman, HE | 1 |
| Weiss, SR | 1 |
| Gant, TW | 1 |
| O'Connor, CK | 1 |
| Corbitt, R | 1 |
| Thorgeirsson, U | 1 |
| Thorgeirsson, SS | 1 |
| Bassett, DR | 1 |
| Mikkelsen, WM | 1 |
| Buckingham, RB | 1 |
| Block, WD | 1 |
| Sidiq, M | 1 |
| Shakibai, A | 1 |
| DiGaetano, R | 1 |
| Liou, LL | 1 |
| Dakshinamurti, K | 1 |
| LeBlancq, WD | 1 |
| Herchl, R | 1 |
| Havlicek, V | 1 |
| Marsden, CA | 1 |
| Curzon, G | 1 |
| Shoulson, I | 1 |
| Chase, TN | 1 |
| Ahtee, L | 1 |
| Attila, P | 1 |
| Lauhakangas, V | 1 |
| Solkinen, A | 1 |
| Sipilä, J | 1 |
| Sandström, PE | 2 |
| Søderlund, EJ | 1 |
| Omichinski, JG | 1 |
| Dahl, JE | 1 |
| Nelson, SD | 1 |
| Dybing, E | 1 |
| Lewandowski, EM | 1 |
| Combs, AB | 1 |
| Folkers, K | 1 |
| Gibson, T | 1 |
| Grahame, R | 1 |
| Sjöström, R | 1 |
| Ikeda, M | 1 |
| Uesugi, T | 1 |
| Papeschi, R | 1 |
| Randrup, A | 1 |
| Munkvad, I | 1 |
| Fuller, RW | 1 |
| Snoddy, HD | 1 |
| Simon, C | 1 |
| Nehls, R | 1 |
| Malerczyk, V | 1 |
| Toeller, W | 1 |
| Zierott, G | 1 |
| Lehmann, K | 1 |
| Kusus, T | 1 |
| Lydtin, H | 1 |
| Zöllner, N | 1 |
| Duncan, GG | 1 |
| Duncan, TG | 1 |
| Schatanoff, J | 1 |
| Jusko, WJ | 1 |
| Leonards, JR | 1 |
| Levy, G | 1 |
| Freis, ED | 1 |
| Sappington, RF | 1 |
7 trials available for probenecid and Body Weight
| Article | Year |
|---|---|
Effects of halofenate and probenecid on serum lipids and uric acid in hyperlipidemic, hyperuricemic adults.
Topics: Adult; Aged; Body Weight; Cholesterol; Clinical Trials as Topic; Female; Glycolates; Halofenate; Hum | 1977 |
Fenfluramine in man: hypophagia associated with diminished serotonin turnover.
Topics: Adult; Appetite; Body Weight; Clinical Trials as Topic; Depression, Chemical; Dopamine; Feeding and | 1975 |
5-Hydroxyindole acetic acid and homovanillic acid in cerebrospinal fluid in manic-depressive psychosis and the effect of probenecid treatment.
Topics: Adult; Age Factors; Aged; Bipolar Disorder; Body Weight; Clinical Trials as Topic; Female; Half-Life | 1973 |
[Pivampicillin, a new ampicillin derivative (author's transl)].
Topics: Administration, Oral; Adult; Ampicillin; Body Weight; Child, Preschool; Drug Evaluation; Drug Therap | 1974 |
[Saluretic treatment of hypertension and uric acid level in serum. Clinical test of a combination of hydrochlorothiazide and probenecid].
Topics: Adult; Aged; Alanine Transaminase; Blood Glucose; Blood Pressure; Blood Protein Electrophoresis; Bod | 1969 |
Refractory obesity and diabetes.
Topics: Adult; Body Weight; Diabetes Mellitus; Diet, Diabetic; Fasting; Female; Glucose Tolerance Test; Huma | 1968 |
Long-term effect of probenecid on diuretic-induced hyperuricemia.
Topics: Adult; Aged; Blood Chemical Analysis; Blood Pressure Determination; Body Weight; Chlorthalidone; Hum | 1966 |
22 other studies available for probenecid and Body Weight
| Article | Year |
|---|---|
Chronic mild stress augments MPTP induced neurotoxicity in a murine model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adjuvants, Pharmaceutic; Animals; Body Weight; Brain-D | 2017 |
Role of multi-drug resistance-associated protein-1 transporter in statin-induced myopathy.
Topics: Animals; Body Weight; Electron Transport Complex IV; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reduc | 2008 |
Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats.
Topics: Alkaline Phosphatase; Animals; Biliary Tract; Body Weight; Camptothecin; Diarrhea; Drug Interactions | 2013 |
Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress.
Topics: Adolescent; Adult; Anaerobic Threshold; Antioxidants; Ascorbic Acid; Body Composition; Body Weight; | 2007 |
Hyperuricemia and mental retardation with athetosis and self-mutilation.
Topics: Allopurinol; Athetosis; Body Height; Body Weight; Child; Child, Preschool; Chorea; Humans; Infant; I | 1967 |
Studies of uric acid metabolism in glycogen storage disease associated with gouty arthritis.
Topics: Adolescent; Allopurinol; Body Height; Body Weight; Carbon Isotopes; Enzyme Therapy; Glucosephosphate | 1967 |
Relationships among maternal diet, serotonin metabolism at weaning, and protein selection of progeny.
Topics: Animals; Body Weight; Brain; Dietary Proteins; Feeding Behavior; Female; Hydroxyindoleacetic Acid; M | 1982 |
The effect of fasting on 5-hydroxytryptamine metabolism in brain regions of the albino rat.
Topics: Animals; Body Temperature; Body Weight; Brain; Fasting; Fenclonine; Hydroxyindoleacetic Acid; Male; | 1984 |
Differences in brain serotonergic metabolism between nonbulimic and bulimic patients with anorexia nervosa.
Topics: Anorexia Nervosa; Appetite; Body Weight; Brain; Brain Chemistry; Dopamine; Feeding and Eating Disord | 1984 |
In vivo induction of liver P-glycoprotein expression by xenobiotics in monkeys.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Densitometry; Diethyl | 1995 |
Nonparallel changes in brain monoamines of pyridoxine-deficient growing rats.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Brain Stem; Dopamine; Hydroxyindoleacetic Acid; Norep | 1976 |
Effects of altered brain 5-hydroxytryptaminergic activity on brain tryptophan, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid.
Topics: Animals; Body Weight; Brain; Brain Chemistry; Brain Stem; Electric Stimulation; Electrolysis; Hot Te | 1976 |
The fall of homovanillic acid and 5-hydroxyindoleacetic acid concentrations in brains of mice withdrawn from repeated morphine treatment and their restoration by acute morphine administration.
Topics: Animals; Body Weight; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Morphine; M | 1987 |
Evidence for diabetogenic action of bumetanide in mice.
Topics: Animals; Blood Glucose; Body Weight; Bumetanide; Diabetes Mellitus, Experimental; Diuresis; Diuretic | 1988 |
Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Gas Chromatography-Mass Spectrometry; Glutath | 1988 |
Probenecid potentiates the hyperglycaemic effect but reduces the diuretic effect of frusemide in mice.
Topics: Animals; Blood Glucose; Body Weight; Diuretics; Drug Synergism; Female; Furosemide; Glycosuria; Hype | 1986 |
The toxicity of tetrahydrobiopterin: acute and subchronic studies in mice.
Topics: Administration, Oral; Animals; Biopterins; Body Weight; Female; Injections, Intraperitoneal; Kidney | 1986 |
Gout and hyperlipidaemia.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Aspartate Aminotransferases; Body Height; Body Weight; C | 1974 |
Studies on the biliary excretion mechanism of drugs. I. Biliary excretion of azo dyes in the rat.
Topics: Animals; Azo Compounds; Bile; Biological Transport, Active; Body Weight; Chromatography, Thin Layer; | 1973 |
Effect of ECT on dopaminergic and noradrenergic mechanisms. II. Effect on dopamine and noradrenaline concentrations and turnovers.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Dopamine; Electroconvulsive Therapy; Homovanillic Aci | 1974 |
Long-term effects of 4-chloroamphetamine on brain 5-hydroxyindole metabolism in rats.
Topics: Amphetamine; Animals; Body Weight; Brain; Brain Chemistry; Chlorine; Depression, Chemical; Hydroxyin | 1974 |
Riboflavin distribution and elimination in two functionally anephric human patients.
Topics: Adult; Body Weight; Collagen Diseases; Glomerulonephritis; Humans; Kidney; Kinetics; Male; Mathemati | 1970 |