probenecid has been researched along with Bile Duct Obstruction in 5 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cephalexin was given to 24 patients before and after operation on the bile ducts and gall bladder." | 1.25 | Cephalexin levels in human bile in presence of biliary tract disease. ( O'Grady, F; Sales, JE; Sutcliffe, M, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Corbett, CL | 1 |
| Bartholomew, TC | 1 |
| Billing, BH | 2 |
| Summerfield, JA | 1 |
| Chitranukroh, A | 1 |
| Taggart, G | 1 |
| Van der Stock, J | 1 |
| De Schepper, J | 1 |
| Sales, JE | 1 |
| Sutcliffe, M | 1 |
| O'Grady, F | 1 |
1 review available for probenecid and Bile Duct Obstruction
| Article | Year |
|---|---|
[Experimental study on the urinary bilirubin excretion in the dog and its clinical significance].
Topics: Animals; Bilirubin; Cholestasis; Creatinine; Diet; Dogs; Electrophoresis; Female; Glomerular Filtrat | 1969 |
4 other studies available for probenecid and Bile Duct Obstruction
| Article | Year |
|---|---|
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Urinary excretion of bile acids in cholestasis: evidence for renal tubular secretion in man.
Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Ethacrynic Acid; Female; Furosemide; | 1981 |
Enhancement of the urinary excretion of non-sulphated and sulphated radioactive bile acids by sodium acetate in the bile duct obstructed rat.
Topics: Acetates; Acetic Acid; Animals; Bile Acids and Salts; Cholestasis; Glomerular Filtration Rate; Glyco | 1985 |
Cephalexin levels in human bile in presence of biliary tract disease.
Topics: Bile; Bile Ducts; Biliary Tract Diseases; Carrier State; Cephalexin; Cholestasis; Gallbladder; Human | 1972 |