probenecid has been researched along with Behavior Disorders in 15 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetylcholinesterase (AChE) was measured in the cerebrospinal fluid (CSF) of patients with a diagnosis of Huntington's disease, depression, schizophrenia, or mania and also in the CSF of normal subjects." | 3.66 | Cerebrospinal fluid acetylcholinesterase in neuropsychiatric disorders. ( Berger, PA; Davis, KL; Hollister, LE; Livesey, J, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leckman, JF | 2 |
| Cohen, DJ | 3 |
| Shaywitz, BA | 3 |
| Caparulo, BK | 3 |
| Heninger, GR | 1 |
| Bowers, MB | 6 |
| Sturges, JS | 1 |
| Korf, J | 1 |
| van den Burg, W | 1 |
| van den Hoofdakker, RH | 1 |
| Sabelli, HC | 1 |
| Mosnaim, AD | 1 |
| Vazquez, AJ | 1 |
| Giardina, WJ | 1 |
| Borison, RL | 1 |
| Pedemonte, WA | 1 |
| Davis, KL | 1 |
| Hollister, LE | 1 |
| Livesey, J | 1 |
| Berger, PA | 1 |
| Billiard, M | 1 |
| Guilleminault, C | 1 |
| Dement, WC | 1 |
| Study, RE | 1 |
| Lerner, P | 1 |
| Goodwin, FK | 2 |
| van Kammen, DP | 1 |
| Post, RM | 2 |
| Major, LF | 1 |
| Ballenger, JC | 1 |
| Lovenberg, W | 1 |
| Véron, JP | 1 |
| Mérienne, L | 1 |
| Gordon, EK | 2 |
| Oliver, J | 1 |
| Chase, TN | 1 |
| Molnár, G | 1 |
| Fodor, A | 1 |
| Karczag, I | 1 |
| Szilágyi, A | 1 |
| Ujvárosi, I | 1 |
| Chase, RN | 1 |
| Schnur, JA | 1 |
| Brody, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for probenecid and Behavior Disorders
| Article | Year |
|---|---|
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentia | 1976 |
14 other studies available for probenecid and Behavior Disorders
| Article | Year |
|---|---|
CSF monoamine metabolites in child and adult psychiatric patients. A developmental perspective.
Topics: Adolescent; Adult; Age Factors; Aged; Autistic Disorder; Bipolar Disorder; Child; Child, Preschool; | 1980 |
Relationship between estimated premorbid adjustment and CSF homovanillic acid and 5-hydroxyindoleacetic acid levels.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Female; Homovanillic Acid; Humans; Hydroxyi | 1981 |
Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders.
Topics: Adjustment Disorders; Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dopamine; Fem | 1983 |
Cerebrospinal fluid acetylcholinesterase in neuropsychiatric disorders.
Topics: Acetylcholinesterase; Adult; Affective Symptoms; Choline; Circadian Rhythm; Humans; Huntington Disea | 1979 |
A menstruation-linked periodic hypersomnia. Kleine-Levin syndrome or new clinical entity?
Topics: Adolescent; Disorders of Excessive Somnolence; Electroencephalography; Estrogens, Conjugated (USP); | 1975 |
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: studies in psychiatric patients.
Topics: Adolescent; Adult; Aged; Biogenic Amines; Chlorpromazine; Cyclic AMP; Depression; Female; Homovanill | 1979 |
Assessment of cerebrospinal monoamine metabolites in children using the probenecid method.
Topics: Adolescent; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Ma | 1977 |
Dopamine-beta-hydroxylase in the cerebrospinal fluid of psychiatric patients.
Topics: Adolescent; Adult; Aged; Alcoholism; Bipolar Disorder; Depression; Dopamine beta-Hydroxylase; Female | 1978 |
Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. CSF homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Adolescent; Age Factors; Aphasia; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; | 1977 |
[The probenecid test. Evaluation in clinical medicine of cerebral metabolism of serotonin and dopamine].
Topics: Biological Transport, Active; Brain; Depression; Dopamine; Down Syndrome; Humans; Indoleacetic Acids | 1972 |
Effect of probenecid on free 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and its sulphate in human cerebrospinal fluid.
Topics: Biological Transport, Active; Brain; Catechols; Chromatography, Gas; Fluorometry; Glycols; Humans; H | 1973 |
5-Hydroxyindoleacetic acid in cerebrospinal fluid.
Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Ac | 1973 |
Clinical measurements of central dopamine and 5-hydroxytryptamine metabolism: reliability and interpretation of cerebrospinal fluid acid monoamine metabolite measures.
Topics: Age Factors; Central Nervous System; Chemistry, Clinical; Dopamine; Fluorometry; Humans; Hydroxyindo | 1972 |
Parkinsonism-dementia and amyotrophic lateral sclerosis of Guam. Effect of probenecid on monoamine catabolite levels in cerebrospinal fluid.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydrox | 1971 |