probenecid has been researched along with BH4 Deficiency in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is postulated that the seizures and neurological deterioration of the patient were related to a deficiency in the synthesis of biogenic amine neurotransmitters." | 1.26 | Biogenic amine synthesis defect in dihydropteridine reductase deficiency. ( Butler, IJ; Koslow, SH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koslow, SH | 1 |
| Butler, IJ | 1 |
| Okajima, K | 1 |
| Inoue, M | 1 |
| Morino, Y | 1 |
| McKean, CM | 1 |
3 other studies available for probenecid and BH4 Deficiency
| Article | Year |
|---|---|
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindolea | 1977 |
Studies on the mechanism for renal elimination of N-acetylphenylalanine: its pathophysiologic significance in phenylketonuria.
Topics: Animals; Humans; Kidney; Ligation; Male; Nephrectomy; Phenylalanine; Phenylketonurias; Probenecid; P | 1985 |
The effects of high phenylalanine concentrations on serotonin and catecholamine metabolism in the human brain.
Topics: Adolescent; Adult; Amino Acids; Brain; Catecholamines; Chromatography; Dopamine; Humans; Hydroxyindo | 1972 |