probenecid has been researched along with B. burgdorferi Infection in 7 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the safety and efficacy of azithromycin, amoxicillin/probenecid, and doxycycline for the treatment of early Lyme disease, to identify risk factors for treatment failure, and to describe the serologic response in treated patients." | 5.07 | Treatment of early Lyme disease. ( Johnson, RC; Luger, SW; Massarotti, EM; Messner, RP; Rahn, DW; Steere, AC; Wong, JB, 1992) |
| " burgdorferi to survive in the former erythema migrans sites of our antibiotic-treated patients, as well as their favorable clinical response, supports the use of doxycycline or combined amoxicillin and probenecid in the treatment of early Lyme disease but does not preclude the survival of the organism in other tissues." | 3.68 | Failure of Borrelia burgdorferi to survive in the skin of patients with antibiotic-treated Lyme disease. ( Berger, BW; Coleman, L; Johnson, RC; Kodner, C, 1992) |
| "Two treatment regimens for disseminated Lyme borreliosis (mainly neurologic and musculoskeletal manifestations) were compared in a randomized trial." | 2.69 | Comparison of oral cefixime and intravenous ceftriaxone followed by oral amoxicillin in disseminated Lyme borreliosis. ( Nikoskelainen, J; Oksi, J; Viljanen, MK, 1998) |
| "72 adults with erythema migrans (early Lyme borreliosis) were enrolled in a randomised prospective trial comparing amoxycillin 500 mg plus probenecid 500 mg three times a day with doxycycline 100 mg twice a day for 21 days." | 2.67 | Amoxycillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis. ( Conaty, SM; Dattwyler, RJ; Luft, BJ; Platkin, SP; Volkman, DJ, 1990) |
| "Lyme disease has probably been reported for at least 80 years, with the cause unknown until the discovery of the Ixodes ricinus complex tick-borne spirochete B." | 1.28 | The diagnosis and treatment of Lyme disease. ( Bair, GO, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayes, E | 1 |
| Steere, AC | 2 |
| Levin, RE | 1 |
| Molloy, PJ | 1 |
| Kalish, RA | 1 |
| Abraham, JH | 1 |
| Liu, NY | 1 |
| Schmid, CH | 1 |
| Oksi, J | 1 |
| Nikoskelainen, J | 1 |
| Viljanen, MK | 1 |
| Massarotti, EM | 1 |
| Luger, SW | 1 |
| Rahn, DW | 1 |
| Messner, RP | 1 |
| Wong, JB | 1 |
| Johnson, RC | 2 |
| Bair, GO | 1 |
| Berger, BW | 1 |
| Kodner, C | 1 |
| Coleman, L | 1 |
| Dattwyler, RJ | 1 |
| Volkman, DJ | 1 |
| Conaty, SM | 1 |
| Platkin, SP | 1 |
| Luft, BJ | 1 |
1 review available for probenecid and B. burgdorferi Infection
| Article | Year |
|---|---|
Lyme disease.
Topics: Adolescent; Adult; Aged; Amoxicillin; Animals; Bacterial Vaccines; Bites and Stings; Borrelia burgdo | 2002 |
4 trials available for probenecid and B. burgdorferi Infection
| Article | Year |
|---|---|
Treatment of Lyme arthritis.
Topics: Adolescent; Adult; Aged; Amoxicillin; Ceftriaxone; Doxycycline; Drug Therapy, Combination; Female; F | 1994 |
Comparison of oral cefixime and intravenous ceftriaxone followed by oral amoxicillin in disseminated Lyme borreliosis.
Topics: Administration, Oral; Adult; Amoxicillin; Cefixime; Cefotaxime; Ceftriaxone; Cephalosporins; Drug Ad | 1998 |
Treatment of early Lyme disease.
Topics: Adult; Amoxicillin; Antibodies, Bacterial; Azithromycin; Borrelia burgdorferi Group; Doxycycline; Er | 1992 |
Amoxycillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis.
Topics: Adult; Amoxicillin; Doxycycline; Drug Therapy, Combination; Female; Humans; Lyme Disease; Male; Prob | 1990 |
2 other studies available for probenecid and B. burgdorferi Infection
| Article | Year |
|---|---|
The diagnosis and treatment of Lyme disease.
Topics: Amoxicillin; Ceftriaxone; Humans; Lyme Disease; Probenecid | 1992 |
Failure of Borrelia burgdorferi to survive in the skin of patients with antibiotic-treated Lyme disease.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Borrelia burgdorferi Group; Doxycycline; Erythema M | 1992 |