probenecid has been researched along with Atrophy in 1 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with probenecid prevented increased plasma creatinine and tubulointerstitial injuries, and reduced both the extent and the severity of ultrastructural lesions induced by aristolochic acid, such as the loss of brush border, mitochondrial edema, and the disappearance of mitochondrial crests." | 1.38 | Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy. ( Antoine, MH; Arlt, VM; Baudoux, TE; De Prez, EG; Goujon, JM; Nortier, JL; Pozdzik, AA; Quellard, N, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baudoux, TE | 1 |
| Pozdzik, AA | 1 |
| Arlt, VM | 1 |
| De Prez, EG | 1 |
| Antoine, MH | 1 |
| Quellard, N | 1 |
| Goujon, JM | 1 |
| Nortier, JL | 1 |
1 other study available for probenecid and Atrophy
| Article | Year |
|---|---|
Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy.
Topics: Animals; Aristolochic Acids; Atrophy; Biomarkers; Cell Proliferation; Cell Survival; Creatinine; Cyt | 2012 |