Page last updated: 2024-11-03

probenecid and Arthritis

probenecid has been researched along with Arthritis in 29 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
"Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism."4.77Hyperuricemia and gout. ( German, DC; Holmes, EW, 1986)
" Injectable gold compounds and penicillamine are not contraindicated in the elderly, because they are just as efficacious as in younger persons for the treatment of rheumatoid arthritis."4.76Problems of antiarthritic therapy in the elderly. ( Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF, 1984)
"We report a patient who, while receiving probenecid and colchicine for acute gouty arthritis, developed severe hemolytic anemia in association with a generalized rash."3.67Probenecid induced immune hemolytic anemia. ( Buck, S; Kickler, TS; Ness, P; Shirey, RS; Sholar, PW, 1986)
" The drug is particularly useful in patients with chronic gouty arthritis and tophi, either refractory or allergic to probenecid, sulfinpyrazone, or allopurinol."3.65Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. ( Yu, TF, 1976)
"The characteristic phenomena of acute gouty arthritis are acute arthritis in a middle-aged male, associated with serum uric acid above 6 mg."3.63Diagnosis and treatment of gouty arthritis. ( TALBOTT, JH, 1953)
"Childhood gonorrhea is most commonly manifested as vulvovaginitis in girls or urethritis in boys, usually without associated disseminated gonococcal infection."2.35Neonatal and childhood gonococcal infections. ( Brooks, GF; Israel, KS; Rissing, KB, 1975)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199028 (96.55)18.7374
1990's0 (0.00)18.2507
2000's1 (3.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TALBOTT, JH2
FELHENDLER, M1
SVENDSEN, HM1
HOLLANDER, E1
MASON, RM1
STERN, FH1
BAKER, OA1
WILLIAMSON, CI1
BEETHAM, WP1
CARCASSONNE, Y1
CARVER, M1
Reginato, A1
Paul, H1
Schumacher, HR1
Brooks, PM1
Kean, WF1
Kassam, Y1
Buchanan, WW1
Rodnan, GP1
Henderson, R1
Boss, GR1
Seegmiller, JE1
Emmerson, BT1
Yu, TF1
Israel, KS1
Rissing, KB1
Brooks, GF1
Gottlieb, N1
Grendelmeier, P1
Rodriguez, E1
Patrone, NA1
German, DC1
Holmes, EW1
Kawenoki-Minc, E1
Kickler, TS1
Buck, S1
Ness, P1
Shirey, RS1
Sholar, PW1
Lo, B1
Kelley, WN1
Wyngaarden, JB1
Bluestone, R1
Kippen, I1
Klinenberg, JR1
Rothermich, NO1
Otto, W1
Binder, E1

Reviews

7 reviews available for probenecid and Arthritis

ArticleYear
Problems of antiarthritic therapy in the elderly.
    Journal of the American Geriatrics Society, 1984, Volume: 32, Issue:3

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory

1984
Treatment of the gout and other forms of crystal-induced arthritis.
    Bulletin on the rheumatic diseases, 1982, Volume: 32, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Go

1982
Hyperuricemia and gout. Classification, complications and management.
    The New England journal of medicine, 1979, Jun-28, Volume: 300, Issue:26

    Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human

1979
Drug control of gout and hyperuricaemia.
    Drugs, 1978, Volume: 16, Issue:2

    Topics: Allopurinol; Arthritis; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Naproxen; Phenylbut

1978
Neonatal and childhood gonococcal infections.
    Clinical obstetrics and gynecology, 1975, Volume: 18, Issue:1

    Topics: Ampicillin; Arthritis; Child; Child, Preschool; Female; Gonorrhea; Humans; Infant; Infant, Newborn;

1975
Hyperuricemia and gout.
    The Medical clinics of North America, 1986, Volume: 70, Issue:2

    Topics: Acute Disease; Adult; Allopurinol; Anti-Inflammatory Agents; Arthritis; Arthrography; Calcinosis; Ch

1986
Drug treatment of gout.
    Seminars in drug treatment, 1971, Volume: 1, Issue:2

    Topics: Acute Disease; Allopurinol; Arthritis; Colchicine; Gout; Humans; Orotic Acid; Probenecid; Structure-

1971

Trials

1 trial available for probenecid and Arthritis

ArticleYear
Effect of drugs on urate binding to plasma proteins.
    British medical journal, 1969, Dec-06, Volume: 4, Issue:5683

    Topics: Adult; Allopurinol; Arthritis; Aspirin; Blood Proteins; Chromatography, DEAE-Cellulose; Colchicine;

1969

Other Studies

21 other studies available for probenecid and Arthritis

ArticleYear
Diagnosis and treatment of gouty arthritis.
    California medicine, 1953, Volume: 79, Issue:3

    Topics: Arthritis; Arthritis, Gouty; Colchicine; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid;

1953
Probenecid therapy in rheumatoid arthritis.
    Acta rheumatologica Scandinavica, 1957, Volume: 3, Issue:2

    Topics: Arthritis; Arthritis, Rheumatoid; Humans; Probenecid

1957
[Porbenecid treatment of uratic arthritis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1957, Dec-01, Volume: 77, Issue:23

    Topics: Arthritis; Gout; Humans; Probenecid

1957
[Uricosuria therapy of chronic gout].
    Orvosi hetilap, 1963, Mar-31, Volume: 104

    Topics: Arthritis; Chronic Disease; Gout; Humans; Probenecid; Uric Acid; Urologic Diseases

1963
INFLAMMATORY POLYARTHRITIC DISEASE. IV. GOUT.
    The Journal of the College of General Practitioners, 1963, Volume: 6

    Topics: Arthritis; Aspirin; Chlorothiazide; Colchicine; Gout; Hydrochlorothiazide; Mecamylamine; Pempidine;

1963
GOUT. A FIVE-YEAR REVIEW.
    Pennsylvania medical journal (1928), 1963, Volume: 66

    Topics: Adrenocorticotropic Hormone; Arthritis; Aspirin; Codeine; Colchicine; Diagnosis, Differential; Diet;

1963
MEDICAL GRAND ROUNDS FROM THE UNIVERSITY OF ALABAMA MEDICAL CENTER.
    Southern medical journal, 1964, Volume: 57

    Topics: Arthritis; Colchicine; Gout; Humans; Phenylbutazone; Probenecid; Teaching Rounds; Uric Acid

1964
[THE TREATMENT OF CHRONIC INFLAMMATORY RHEUMATISM IN ADULTS].
    Marseille medical, 1964, Volume: 101

    Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis; Arthritis, Rheumatoid; Aspirin; Colchicine; Colla

1964
ATYPICAL GOUT.
    Journal of the American Podiatry Association, 1964, Volume: 54

    Topics: Arthritis; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Geriatrics; Gout; Humans; Ost

1964
Gout: joint pain and more.
    Harvard men's health watch, 2007, Volume: 12, Issue:5

    Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Gout; Gout Suppressa

2007
Crystal-induced arthritis.
    Archives of physical medicine and rehabilitation, 1982, Volume: 63, Issue:9

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Arthritis; Calcium Pyrophosphate; Crystalli

1982
Recommended treatment schedules for gonorrhea--1974.
    Archives of dermatology, 1975, Volume: 111, Issue:3

    Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Arthritis; Child; Child, Preschool; Coitus; Female; G

1975
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
    The Journal of rheumatology, 1976, Volume: 3, Issue:3

    Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease;

1976
Gouty arthritis in the black race.
    Seminars in arthritis and rheumatism, 1975, Volume: 4, Issue:3

    Topics: Adult; Aged; Anemia, Sickle Cell; Arthritis; Benzothiadiazines; Black People; Colchicine; Diuretics;

1975
Polyarticular gout induced by probenecid therapy.
    North Carolina medical journal, 1986, Volume: 47, Issue:9

    Topics: Aged; Arthritis; Gout; Humans; Male; Probenecid

1986
[Effect of decrease in hyperuricemia levels on joint, kidney and other symptoms in patients with gout].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:4

    Topics: Adult; Aged; Allopurinol; Arthritis; Colchicine; Coronary Disease; Gout; Humans; Hypertension; Middl

1987
Probenecid induced immune hemolytic anemia.
    The Journal of rheumatology, 1986, Volume: 13, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Arthritis; Colchicine; Coombs Test; Drug Therapy, Combination; Gout;

1986
Hyperuricemia and gout.
    The Western journal of medicine, 1985, Volume: 142, Issue:1

    Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Colchicine; Female; Gout; Humans; Indomethacin; Ki

1985
Current therapy of gonorrhea.
    JAMA, 1971, Nov-01, Volume: 218, Issue:5

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Arthritis; Cervix Mucus; Female; Gonorrhea; Huma

1971
An extended study of indomethacin. II. Clinical therapy.
    JAMA, 1966, Mar-28, Volume: 195, Issue:13

    Topics: Adolescent; Adult; Arthritis; Arthritis, Rheumatoid; Aspirin; Child; Female; Gout; Humans; Indometha

1966
[Clinical aspects of chronic gout].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Sep-15, Volume: 21, Issue:18

    Topics: Adult; Aged; Allopurinol; Anemia; Arthritis; Bicarbonates; Blood Sedimentation; Chronic Disease; Fem

1966