probenecid has been researched along with Allodynia in 4 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuropathic pain is still a challenge for clinical treatment as a result of the comprehensive pathogenesis." | 1.72 | Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses. ( Chen, G; Li, HY; Ling, ZM; Wang, Q; Wei, ZY, 2022) |
| "Capsaicin induced both mechanical hyperalgesia/allodynia and heat hyperalgesia." | 1.40 | Activation of transient receptor potential vanilloid 2-expressing primary afferents stimulates synaptic transmission in the deep dorsal horn of the rat spinal cord and elicits mechanical hyperalgesia. ( Barrot, M; Barthas, F; Bohren, Y; Hugel, S; Petitjean, H; Schlichter, R; Yalcin, I, 2014) |
| "l-Kynurenine has antinociceptive effects in acute and inflammatory pain." | 1.39 | The L-kynurenine-probenecid combination reduces neuropathic pain in rats. ( Aguilera, P; Barragán-Iglesias, P; Bravo-Hernández, M; Cervantes-Durán, C; González-Esquivel, DF; Granados-Soto, V; Pérez-Severiano, F; Pineda-Farias, JB; Ríos, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Li, HY | 1 |
| Ling, ZM | 1 |
| Chen, G | 1 |
| Wei, ZY | 1 |
| Pineda-Farias, JB | 1 |
| Pérez-Severiano, F | 1 |
| González-Esquivel, DF | 1 |
| Barragán-Iglesias, P | 1 |
| Bravo-Hernández, M | 1 |
| Cervantes-Durán, C | 1 |
| Aguilera, P | 1 |
| Ríos, C | 1 |
| Granados-Soto, V | 1 |
| Bravo, D | 1 |
| Ibarra, P | 1 |
| Retamal, J | 1 |
| Pelissier, T | 1 |
| Laurido, C | 1 |
| Hernandez, A | 1 |
| Constandil, L | 1 |
| Petitjean, H | 1 |
| Hugel, S | 1 |
| Barthas, F | 1 |
| Bohren, Y | 1 |
| Barrot, M | 1 |
| Yalcin, I | 1 |
| Schlichter, R | 1 |
4 other studies available for probenecid and Allodynia
| Article | Year |
|---|---|
Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses.
Topics: Adenosine Triphosphate; Animals; Carbenoxolone; Connexins; Cytokines; Ethidium; Hyperalgesia; Lipopo | 2022 |
The L-kynurenine-probenecid combination reduces neuropathic pain in rats.
Topics: Animals; Drug Therapy, Combination; Female; Hyperalgesia; Kynurenine; Motor Activity; Neuralgia; Pai | 2013 |
Pannexin 1: a novel participant in neuropathic pain signaling in the rat spinal cord.
Topics: Animals; Carbenoxolone; Connexins; Hyperalgesia; Male; Nerve Tissue Proteins; Neuralgia; Pain Thresh | 2014 |
Activation of transient receptor potential vanilloid 2-expressing primary afferents stimulates synaptic transmission in the deep dorsal horn of the rat spinal cord and elicits mechanical hyperalgesia.
Topics: Afferent Pathways; Animals; Capsaicin; Cells, Cultured; Ganglia, Spinal; Hyperalgesia; Male; Neurons | 2014 |