probenecid has been researched along with Alcoholism in 5 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tunstall, BJ | 1 |
| Lorrai, I | 1 |
| McConnell, SA | 1 |
| Gazo, KL | 1 |
| Zallar, LJ | 1 |
| de Guglielmo, G | 1 |
| Hoang, I | 1 |
| Haass-Koffler, CL | 1 |
| Repunte-Canonigo, V | 1 |
| Koob, GF | 1 |
| Vendruscolo, LF | 1 |
| Sanna, PP | 1 |
| WERMER, PL | 1 |
| Lerner, P | 1 |
| Goodwin, FK | 1 |
| van Kammen, DP | 1 |
| Post, RM | 1 |
| Major, LF | 1 |
| Ballenger, JC | 1 |
| Lovenberg, W | 1 |
| Silbermann, M | 1 |
| Chiminello, FJ | 1 |
| Doku, HC | 1 |
| Maloney, PL | 1 |
| Ahtee, L | 1 |
| Eriksson, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Probenecid as Pharmacotherapy for Alcohol Use Disorder[NCT04218357] | Phase 1 | 34 participants (Anticipated) | Interventional | 2020-12-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for probenecid and Alcoholism
| Article | Year |
|---|---|
Probenecid Reduces Alcohol Drinking in Rodents. Is Pannexin1 a Novel Therapeutic Target for Alcohol Use Disorder?
Topics: Adjuvants, Pharmaceutic; Alcohol Drinking; Alcoholism; Animals; Connexins; Dose-Response Relationshi | 2019 |
Newer approved drugs and drugs under clinical study.
Topics: Alcoholism; Biomedical Research; Dermatitis, Seborrheic; Disulfiram; Drug Approval; Pharmaceutical P | 1952 |
Dopamine-beta-hydroxylase in the cerebrospinal fluid of psychiatric patients.
Topics: Adolescent; Adult; Aged; Alcoholism; Bipolar Disorder; Depression; Dopamine beta-Hydroxylase; Female | 1978 |
Mandibular actinomycosis: report of case.
Topics: Actinomyces; Actinomycosis, Cervicofacial; Adult; Alcoholism; Anesthesia, Local; Female; Fracture Fi | 1975 |
5-Hydroxytryptamine and 5-hydroxyindolylacetic acid content in brain of rat strains selected for their alcohol intake.
Topics: Alcohol Drinking; Alcoholism; Animals; Body Temperature; Brain; Brain Chemistry; Disease Models, Ani | 1972 |